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  4. Recombinant Bartonella henselae Type IV secretion system protein VirB11 (virB11)

Recombinant Bartonella henselae Type IV secretion system protein VirB11 (virB11)

  • 中文名稱：
    Recombinant Bartonella henselae Type IV secretion system protein VirB11(virB11)
  • 貨號：
    CSB-YP890167BSG
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Bartonella henselae Type IV secretion system protein VirB11(virB11)
  • 貨號：
    CSB-EP890167BSG
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Bartonella henselae Type IV secretion system protein VirB11(virB11)
  • 貨號：
    CSB-EP890167BSG-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Bartonella henselae Type IV secretion system protein VirB11(virB11)
  • 貨號：
    CSB-BP890167BSG
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Bartonella henselae Type IV secretion system protein VirB11(virB11)
  • 貨號：
    CSB-MP890167BSG
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    virB11
  • Uniprot No.：
  • 別名：
    virB11; BH13350Type IV secretion system protein VirB11
  • 種屬：
    Bartonella henselae (strain ATCC 49882 / Houston 1) (Rochalimaea henselae)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-356
  • 氨基酸序列
    MNQNLHTLSD ETVAIVLTKL EPISTFLKDE NLFEIVINRP YQVMTEGVEG WKTIETPALS FNELMGIAKV VASYSKQNIS EKNPILSATL PGNERIQIVI PPAVEKNTIS MTIRKPSSRS FSLEDLANKG LFSVCEQVSF TPLNNYLSHL SELKHIDHDL VRAYAKKDFV FFLNQAVQCQ KNILIAGKTG SGKTTLSKAL IAKIPDDERI ITIEDTPELV VPQPNYVSMI YSKDGQGLAS VGPKELLESA LRMRPDRILL QELRDGTAFY YIRNVNSGHP GSITTVHAST ALAAFEQMTL LVKESEGGGD LERDDIRGLL ISMIDIIIQC KRIEGKFKVT EIYYDPFKQR NIFGGN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    The type IV secretion system VirB/VirD4 is a major virulence determinant for subversion of human endothelial cell (HEC) function. VirB-dependent changes of HEC include massive cytoskeletal rearrangements, a proinflammatory activation by nuclear factor NF-kappa-B, inhibition of early and late events of apoptosis, leading to an increased cell survival, and, at high infection doses, a cytostatic or cytotoxic effect, which interfers with a potent VirB-independent mitogenic activity. These changes of HEC require the T4S coupling protein VirD4 and at least one of the effector proteins BepA-G. Altogether with VirB4, may be implicated in providing the energy, via hydrolysis of ATP, for the assembly of secretion system and substrate transport.
  • 亞細胞定位：
    Cell inner membrane.
  • 蛋白家族：
    GSP E family
  • 數據庫鏈接：

    KEGG: bhe:BH13350

    STRING: 283166.BH13350



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