在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant BK polyomavirus Large T antigen, partial

  • 中文名稱:
    Recombinant BK polyomavirus Large T antigen, partial
  • 貨號(hào):
    CSB-EP360947BGY
  • 規(guī)格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    N/A
  • Uniprot No.:
  • 別名:
    LT;LT-AG
  • 種屬:
    BK polyomavirus (BKPyV) (Human polyomavirus 1)
  • 蛋白長(zhǎng)度:
    Partial
  • 來(lái)源:
    E.coli
  • 分子量:
    22.7 kDa
  • 表達(dá)區(qū)域:
    1-133aa
  • 氨基酸序列
    MDKVLNREESMELMDLLGLERAAWGNLPLMRKAYLRKCKEFHPDKGGDEDKMKRMNTLYKKMEQDVKVAHQPDFGTWSSSEVPTYGTEEWESWWSSFNEKWDEDLFCHEDMFASDEEATADSQHSTPPKKKRK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-tagged and C-terminal Avi-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA. Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA. Participates in the modulation of cellular gene expression preceeding viral DNA replication. This step involves binding to host key cell cycle regulators retinoblastoma protein RB1/pRb and TP53. Induces the disassembly of host E2F1 transcription factors from RB1, thus promoting transcriptional activation of E2F1-regulated S-phase genes. Inhibits host TP53 binding to DNA, abrogating the ability of TP53 to stimulate gene expression. Plays the role of a TFIID-associated factor (TAF) in transcription initiation for all three RNA polymerases, by stabilizing the TBP-TFIIA complex on promoters. Initiates viral DNA replication and unwinding via interactions with the viral origin of replication. Binds two adjacent sites in the SV40 origin. The replication fork movement is facilitated by Large T antigen helicase activity. Activates the transcription of viral late mRNA, through host TBP and TFIIA stabilization. Interferes with histone deacetylation mediated by HDAC1, leading to activation of transcription.
  • 亞細(xì)胞定位:
    Host nucleus.
  • 數(shù)據(jù)庫(kù)鏈接:

    KEGG: vg:29031009



主站蜘蛛池模板: 久久综合99re88久久爱| 野外做受三级视频| 人妻丰满熟妞av无码区| 国产精品狼人久久久久影院| 少妇被粗大的猛进出69影院| 真人床震高潮全部视频免费| 波多野结衣在线观看一码| 亚洲欧洲成人av每日更新| 国产免费人成在线视频app| 在线观看片a免费不卡观看| 一个人看的日本hd免费| 波多野结衣av在线无码中文18| www内射国产在线观看| 奶头好大狂揉60分钟视频| 亚洲国产成人综合精品| 亚洲狠狠色成人综合网| 精品国产午夜福利在线观看| 人人妻人人澡人人爽人人精品| 苍井空亚洲精品aa片在线播放| 国产精品美脚玉足脚交| 亚洲 欧美 国产 动漫 综合| 色77久久综合网| 在线观看黄a∨免费无毒网站| 18禁止观看强奷免费国产大片| 日韩欧美亚洲国产精品字幕久久久| 色拍拍在线精品视频| 伦理片午夜视频在线观看| 精品国产自在现线电影| 免费人成视频x8x8| 1000部又爽又黄无遮挡的视频 | 在线看亚洲十八禁网站| 亚洲日韩国产二区无码| 日韩成人无码v清免费| 丰满少妇大力进入| 国内精品免费久久久久电影院| 美女被张开双腿日出白浆| 国产成人精品日本亚洲语音| 亚洲人成无码网站久久99热国产| 亚洲 欧美 成人 自拍 高清| 777米奇色狠狠俺去啦| 中文字幕人妻无码视频|