在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Arabidopsis thaliana Two pore calcium channel protein 1 (TPC1), partial

Recombinant Arabidopsis thaliana Two pore calcium channel protein 1 (TPC1), partial

  • 中文名稱：
    擬南芥TPC1重組蛋白
  • 貨號：
    CSB-YP853237DOA
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    擬南芥TPC1重組蛋白
  • 貨號：
    CSB-EP853237DOA
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    擬南芥TPC1重組蛋白
  • 貨號：
    CSB-EP853237DOA-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    擬南芥TPC1重組蛋白
  • 貨號：
    CSB-BP853237DOA
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    擬南芥TPC1重組蛋白
  • 貨號：
    CSB-MP853237DOA
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    TPC1
  • Uniprot No.：
  • 別名：
    TPC1; CCH1; FOU2; At4g03560; F9H3.19; T5L23.5; Two pore calcium channel protein 1; Calcium channel protein 1; AtCCH1; Fatty acid oxygenation up-regulated protein 2; Voltage-dependent calcium channel protein TPC1; AtTPC1
  • 種屬：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Functions as a voltage-gated inward-rectifying Ca(2+) channel (VDCC) across the vacuole membrane. Is one of the essential components of the slow vacuolar (SV) channel. Acts as the major ROS-responsive Ca(2+) channel and is the possible target of Al-dependent inhibition. Involved in the regulation of germination and stomatal movement.
  • 基因功能參考文獻：
    1. Structural basis for activation of voltage sensor domains in an ion channel TPC1. PMID: 30190435
    2. variant (TPC1D454N) depolarizes endomembranes by increasing cation fluxes towards the cytosol PMID: 28885692
    3. The ion selectivity of AtTPC1 was determined and compared with the selectivity of human TPC2. TPC1 is selective for Ca(2+) over Na(+), but nonselective among monovalent Li(+), Na(+), and K(+)). AtTPC1 could be converted to a Na(+)-selective channel by mimicking the selectivity filter of HsTPC2. Key residues were identified in the TPC filters that differentiate this selectivity. A Na+-selective mutant was characterized. PMID: 28096396
    4. TPC1 role in the systemic response to salt stress PMID: 27261066
    5. Structure-function analysis of the Arabidopsis TPC1 channel in planta confirmed that helix S10 operates as the major voltage-sensing site, with Glu450 and Glu478 identified as possible ion-pair partners for voltage-sensing Arg537. PMID: 27270880
    6. The domain architecture of TPC1 has been discussed. PMID: 27156118
    7. This study discovered that the dimerization of a predicted helix within the carboxyl-terminus is essential for the activity of TPC1. PMID: 26781468
    8. crystal structure of TPC1 from Arabidopsis thaliana at 2.87 A resolution as a basis for understanding ion permeation, channel activation, the location of voltage-sensing domains and regulatory ion-binding sites PMID: 26961658
    9. crystal structure of a vacuolar two-pore channel from Arabidopsis thaliana, AtTPC1, which functions as a homodimer PMID: 26689363
    10. The SV channel fou2 mutation in TCP1 altered sensitivity to luminal Ca2+ levels. PMID: 19298454
    11. TPC1 contains a N-terminal dileucine motif (EDPLI) critical for vacuolar targeting PMID: 22490017
    12. TPC1 has a role in maintaining differential K and Ca storage across the leaf; it releases Ca2+ from epidermal and bundle sheath cell vacuoles to maintain low [Ca]vac. PMID: 22067997
    13. EF-hand 1 modulates the Ca2+-sensitivity of TPC1, whereas EF-hand 2 is essential for the Ca2+-dependent channel opening. PMID: 21736651
    14. Results indicate that Glu-450 and Asp-454 of the slow vacuolar channel TPC1 are directly involved in Ca2+ binding, whereas Glu-456 and Glu-457 are probably involved in connecting the luminal Ca2+ binding site to the channel gate. PMID: 21764990
    15. AtTPC1 functions in response to external Ca2+ but not to abscisic acid and methyl jasmonate in Arabidopsis guard cells. PMID: 20061305
    16. Results suggest that members of TPC1 channel family are reactive oxygen species-responsive calcium channels and are the possible targets of aluminum-dependent inhibition. PMID: 15464979
    17. a tpc1 knockout mutant lacks functional slow vacuolar channel activity and is defective in both abscisic acid-induced repression of germination and in the response of stomata to extracellular calcium PMID: 15772667
    18. a genetic screen capable of detecting the misregulated activity of 13-lipoxygenase identified a missense mutation in TPC1, indicating that cation fluxes exert control over positive feedback loop for jasmonic acid stimulates its own synthesis. PMID: 17253984
    19. results suggest that wild-type TPC1 contributes to their expression of PDF1.2a and THI2 by mechanisms somewhat different from those affecting their expression in fou2 PMID: 17981874
    20. study found loss of TPC1 did not change membrane hyperpolarization-activated Ca(2+)-permeable channel activity; we conclude TPC1, under physiological conditions, functions as a vacuolar cation channel without major impact on cytosolic Ca(2+) homeostasis PMID: 18028262

    顯示更多

    收起更多

  • 亞細胞定位：
    Vacuole membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Calcium channel alpha-1 subunit (TC 1.A.1.11) family, Two pore calcium channel subfamily
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：

    KEGG: ath:AT4G03560

    STRING: 3702.AT4G03560.1

    UniGene: At.3957



主站蜘蛛池模板： 亚洲日韩一区二区| 熟女chachacha性少妇| 717影院理论午夜伦八戒| 无套中出丰满人妻无码| 国产精品无码免费专区午夜| 久久av无码aⅴ高潮av喷吹| 欧美性猛交xxxx富婆| 亚洲性无码av在线| 人人狠狠综合久久亚洲爱咲| 成人小说亚洲一区二区三区| 国产肥白大熟妇bbbb视频| 亚洲偷自拍国综合| 国产1卡2卡3卡4卡免费| 人体内射精一区二区三区| 中文字幕在线日亚州9| 精产国品一区二区三产区| 男女久久久国产一区二区三区| 亚洲女同一区二区| 久久精品久久电影免费理论片| 蜜臀av99无码精品国产专区| 天天躁日日躁aaaxxⅹ| 欧美成人午夜免费影院手机在线看| 黄网在线观看免费网站| 无码人妻视频一区二区三区| 丁香五月综合久久激情| 国产精品玩偶在线观看| 亚洲精品一区二区三区四区乱码| 无码人妻精品一区二区三区东京热| 国产在线看片免费视频| 国产精品va在线播放| 99久热在线精品视频观看| 中文天堂在线www最新版官网| 又爽又黄无遮挡高潮视频网站| 成人区人妻精品一区二区不卡网站| 高清一区二区三区日本久| 亚洲精品久久一区二区三区四区| 少妇爽到呻吟的视频| 成人试看120秒体验区| 老熟女毛茸茸浓毛| 亚洲中文字幕在线精品2021| 大色综合色综合网站|