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Recombinant Arabidopsis thaliana Casein kinase II subunit alpha-2 (CKA2)

  • 中文名稱:
    Recombinant Arabidopsis thaliana Casein kinase II subunit alpha-2(CKA2)
  • 貨號:
    CSB-YP600863DOA
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Arabidopsis thaliana Casein kinase II subunit alpha-2(CKA2)
  • 貨號:
    CSB-EP600863DOA
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Arabidopsis thaliana Casein kinase II subunit alpha-2(CKA2)
  • 貨號:
    CSB-EP600863DOA-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Arabidopsis thaliana Casein kinase II subunit alpha-2(CKA2)
  • 貨號:
    CSB-BP600863DOA
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Arabidopsis thaliana Casein kinase II subunit alpha-2(CKA2)
  • 貨號:
    CSB-MP600863DOA
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CKA2
  • Uniprot No.:
  • 別名:
    CKA2; At3g50000; F3A4.80Casein kinase II subunit alpha-2; CK II; EC 2.7.11.1; Casein kinase alpha 2; AtCKA2
  • 種屬:
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    32-403
  • 氨基酸序列
    LIPPLTCVN TGTVESDVTG IRFDRCLDTD SLAKISLSTV MSKARVYTDV NVIRPKDYWD YESLNVQWGE QDDYEVVRKV GRGKYSEVFE GINMNNNEKC IIKILKPVKK KKIRREIKIL QNLCGGPNIV KLLDVVRDQH SKTPSLIFEY VNSTDFKVLY PTLTDYDIRY YIYELLKALD FCHSQGIMHR DVKPHNVMID HELRKLRLID WGLAEFYHPG KEYNVRVASR YFKGPELLVD LQDYDYSLDM WSLGCMFAGM IFRKEPFFYG HDNQDQLVKI AKVLGTDELN AYLNKYQLEL DTQLEALVGR HSRKPWSKFI NADNRHLVSP EAIDYLDKLL RYDHQDRLTA KEAMAHPYFA QVRAAESSRM RTQ
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site. The tetrameric holoenzyme CK2, composed of two alpha and two beta subunits, phosphorylates the transcription factor PIF1 after an exposure to light, resulting in a proteasome-dependent degradation of PIF1 and promotion of photomorphogenesis. CK2 phosphorylates translation initiation factors. May participate in the regulation of the initiation of translation. Acts as circadian clock component that maintains the correct period length through phosphorylation of CCA1. May act as an ectokinase that phosphorylates several extracellular proteins.
  • 基因功能參考文獻:
    1. CK2 activity increases the roots endogenous salicylic acid levels, indicating that CK2 activity is required for SA biosynthesis.CK2 is transcriptionally regulated by salicylic acid. PMID: 24547808
    2. CK2 is required in the maintenance and control of genomic stability and chromatin structure in plants, and that this process affects several functions, including the DNA damage response and DNA repair.[CK2] PMID: 22487192
    3. CK2 activity depletion affects auxin-dependent processes, and particularly auxin transport. PMID: 21435053
    4. The effects of a cka1a2a3 triple mutant on the Arabidopsis (Arabidopsis thaliana) circadian clock, were examined. PMID: 21900482
    5. alpha1 and alpha2 subunits of CK2 individually phosphorylated phytochrome interacting factors weakly in vitro. PMID: 21330376

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  • 亞細胞定位:
    Nucleus. Nucleus, nucleolus.
  • 蛋白家族:
    Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily
  • 組織特異性:
    Seems to be present in all plant organs. But seems to be more expressed than CKA1.
  • 數據庫鏈接:

    KEGG: ath:AT3G50000

    STRING: 3702.AT3G50000.1

    UniGene: At.268



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