在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Androctonus mauretanicus mauretanicus Alpha-toxin Amm8

  • 中文名稱:
    Recombinant Androctonus mauretanicus mauretanicus Alpha-toxin Amm8
  • 品名簡稱:
    Recombinant Androctonus mauretanicus mauretanicus Alpha-toxin Amm8 protein
  • 貨號:
    CSB-EP773772AKB
  • 說明書:
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    N/A
  • Uniprot No.:
  • 別名:
    ; Alpha-toxin Amm8; Alpha-anatoxin Amm VIII; Amm VIII; AmmVIII; Neurotoxin 8; P4
  • 種屬:
    Androctonus mauritanicus mauritanicus(Scorpion)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    14.8 kDa
  • 表達區域:
    20-84aa
  • 氨基酸序列
    LKDGYIVNDINCTYFCGRNAYCNELCIKLKGESGYCQWASPYGNSCYCYKLPDHVRTKGPGRCND
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. The toxin principally slows the inactivation process of TTX-sensitive sodium channels. It discriminates neuronal versus muscular sodium channel, as it is more potent on rat brain Nav1.2/SCN2A (EC(50)=29 nM) than on rat skeletal muscle Nav1.4/SCN4A (EC(50)=416 nM). It also shows a weak activity on Nav1.7/SCN9A (EC(50)=1.76 uM). In vivo, the toxin produces pain hypersensibility to mechanical and thermal stimuli.(PubMed:23685008). It also exhibits potent analgesic activity (when injected intraperitoneally), increasing hot plate and tail flick withdrawal latencies in a dose-dependent fashion. This paradoxical analgesic action, is significantly suppressed by opioid receptor antagonists, suggesting a pain-induced analgesia mechanism that involves an endogenous opioid system. This led to hypothesis that pain relief induced by peripheral administration of Amm VIII may result from sensitization of primary afferent neurons and subsequent activation of an opioid-dependent noxious inhibitory control.
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Long (4 C-C) scorpion toxin superfamily, Sodium channel inhibitor family, Alpha subfamily
  • 組織特異性:
    Expressed by the venom gland.


主站蜘蛛池模板: 亚洲精品天天影视综合网| 国产日韩另类综合11页| 97影院理论午夜伦不卡| 宅男宅女精品国产av天堂| 亚洲日本中文字幕乱码在线| 欧美日韩无砖专区一中文字| 免费国产精品视频在线| а√最新版在线天堂| 国产全是老熟女太爽了| 日韩免费视频| 九九久久精品国产av片国产| 午夜精品久久久内射近拍高清 | 老太脱裤让老头玩ⅹxxxx| 色综合99久久久无码国产精品 | 艳妇乳肉豪妇荡乳xxx| 国产av人人夜夜澡人人爽| 国产av中文av无码av狼人| 高清国产av一区二区三区| 亚洲丁香婷婷久久一区二区| 天天躁日日躁狠狠躁av| 人妻少妇heyzo无码专区 | 欧美亚洲另类 丝袜综合网| 欧美丰满大爆乳波霸奶水多| 波多野结衣初尝黑人| 亚洲人成无码网站久久99热国产| k频道国产在线观看| 欧美丰满肥婆videos| 色777狠狠狠综合| 免免费国产aaaaa片| 成人免费视频一区二区三区| 国产精品乱码一区二区三| 无码任你躁久久久久久老妇蜜桃| 亚洲伊人久久成人综合网| 国产精品毛片无遮挡高清| 无码国产乱人伦偷精品视频| 国产精品高潮露脸在线观看| 女高中生自慰污污网站| 午夜亚洲福利在线老司机| 日韩一区二区三区无码影院| 亚洲高清有码中文字| 久久99av无色码人妻蜜|