在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PDHB Recombinant Monoclonal Antibody

  • 中文名稱:
    PDHB Recombinant Monoclonal Antibody
  • 貨號:
    CSB-RA616398A0HU
  • 規格:
    ¥1320
  • 圖片:
    • Western Blot
      Positive WB detected in: U-251MG whole cell lysate(20μg),Hela whole cell lysate(20μg),HepG2 whole cell lysate(20μg),Jurkat whole cell lysate(20μg),HL-60 whole cell lysate(20μg),K562 whole cell lysate(20μg),U-937 whole cell lysate(20μg),Mouse brain tissue lysate(20μg),Rat brain tissue lysate(20μg)
      All lanes: PDHB antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/40000 dilution
      Predicted band size: 39 kDa
      Observed band size: 37 kDa
      Exposure time:2min
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    DKFZp564K0164 antibody; mitochondrial antibody; ODPB_HUMAN antibody; pdhB antibody; PDHBD antibody; PDHE1 B antibody; PDHE1-B antibody; PHE1B antibody; Pyruvate dehydrogenase (lipoamide) beta antibody; Pyruvate dehydrogenase E1 beta polypeptide antibody; Pyruvate dehydrogenase E1 component subunit beta antibody; Pyruvate dehydrogenase E1 component subunit beta mitochondrial antibody
  • 反應種屬:
    Human, Mouse, Rat
  • 免疫原:
    A synthesized peptide derived from human PDHB
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Monoclonal
  • 抗體亞型:
    Rabbit IgG
  • 純化方式:
    Affinity-chromatography
  • 克隆號:
    19E3
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
  • 基因功能參考文獻:
    1. PDHB was downregulated in nasopharyngeal carcinoma cells. Forced expression of PDHB in NPC cells inhibited cell growth and migration, while knocking down the expression of PDHB promoted the growth, migration, and tumorigenesis of NPC cells. PDHB inhibited ERK signaling and cell growth driven by RasV12. PMID: 26857147
    2. Data indicate that (pro)renin receptor ATP6PA2 interacts with the E1 beta subunit of pyruvate dehydrogenase and controlling its protein stability PMID: 25720494
    3. PHD3 depletion did not affect the expression of the PDH-E1alpha, E1beta, and E2 subunits, or the phosphorylation status of E1alpha, but destabilized the PDH complex (PDC), resulting in less functional PDC. PMID: 25088999
    4. Sequencing of PDHB reveals a homozygous point mutation (c.302T>C), causing a predicted amino acid change in patient 1. Patient 2 is compound heterozygote for mutations c.301A>G (p.M101V) and c.313G>A (p.R105Q). PMID: 19924563
    5. Data indicate that PDH deficiency in our patient involves a post-translational modification in which EGFR-PTK-mediated tyrosine phosphorylation of the E1beta protein leads to enhanced ubiquitination followed by proteasome-mediated degradation. PMID: 17923481
    6. clinical findings are similar to those of PDHA1 deficiency, except that ataxia was more frequent in PDHA1 cases and consanguinity was found only in PDHB families. PMID: 18164639
    7. Species specificity in the interaction between hE1beta and hE2 in pyruvate dehydrogenase complex. PMID: 18206651

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Pyruvate dehydrogenase E1-beta deficiency (PDHBD)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 數據庫鏈接:

    HGNC: 8808

    OMIM: 179060

    KEGG: hsa:5162

    STRING: 9606.ENSP00000307241

    UniGene: Hs.161357



主站蜘蛛池模板: 国产日韩亚洲大尺度高清 | 成 人 社区在线视频| 黑人巨大av在线播放无码| 午夜性刺激在线视频免费 | 久久青草成人综合网站| 欧美又黄又大又爽a片三年片| 国产香蕉97碰碰久久人人| 久久亚洲中文字幕无码| 中文www新版资源在线| 亚洲成色最大综合在线| 伦理片无码电影在线看| 无码喷水一区二区浪潮av| 欧美精品黑人粗大视频| 欧洲熟妇色xxxx欧美老妇多毛网站| 色悠久久久久综合网香蕉| 国产成人精品三级在线影院 | 少妇群交换bd高清国语版| 免费久久人人爽人人爽av| 欧美成人一区二免费视频| 国产成人午夜福利在线小电影| 精品国产中文字幕在线视频| 免费无码又爽又刺激聊天app | 乱码国产丰满人妻www| 成人做爰69片免费看网站| 美女裸体十八禁免费网站| 无码动漫性爽xo视频在线观看 | 国产又黄又大又粗的视频| 日韩亚洲欧美中文在线| 欧美视频网站www色| 肉色欧美久久久久久久免费看| 97se亚洲精品一区| 在线视频夫妻内射| av无码动漫一区二区三区精品| 亚洲色无码中文字幕在线| 国产精品久久久福利| 97免费人妻无码视频| 99久久久无码国产精品动漫| 亚洲成a人v电影在线观看 | 欧美激情精品成人一区| 熟妇五十路六十路息与子| 2020精品国产自在现线看|