在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PDHB Antibody

  • 中文名稱:
    PDHB兔多克隆抗體
  • 貨號:
    CSB-PA017717ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA017717ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA017717ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PDHB Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    DKFZp564K0164 antibody; mitochondrial antibody; ODPB_HUMAN antibody; pdhB antibody; PDHBD antibody; PDHE1 B antibody; PDHE1-B antibody; PHE1B antibody; Pyruvate dehydrogenase (lipoamide) beta antibody; Pyruvate dehydrogenase E1 beta polypeptide antibody; Pyruvate dehydrogenase E1 component subunit beta antibody; Pyruvate dehydrogenase E1 component subunit beta mitochondrial antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Pyruvate dehydrogenase E1 component subunit beta, mitochondrial protein (1-300AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
  • 基因功能參考文獻:
    1. PDHB was downregulated in nasopharyngeal carcinoma cells. Forced expression of PDHB in NPC cells inhibited cell growth and migration, while knocking down the expression of PDHB promoted the growth, migration, and tumorigenesis of NPC cells. PDHB inhibited ERK signaling and cell growth driven by RasV12. PMID: 26857147
    2. Data indicate that (pro)renin receptor ATP6PA2 interacts with the E1 beta subunit of pyruvate dehydrogenase and controlling its protein stability PMID: 25720494
    3. PHD3 depletion did not affect the expression of the PDH-E1alpha, E1beta, and E2 subunits, or the phosphorylation status of E1alpha, but destabilized the PDH complex (PDC), resulting in less functional PDC. PMID: 25088999
    4. Sequencing of PDHB reveals a homozygous point mutation (c.302T>C), causing a predicted amino acid change in patient 1. Patient 2 is compound heterozygote for mutations c.301A>G (p.M101V) and c.313G>A (p.R105Q). PMID: 19924563
    5. Data indicate that PDH deficiency in our patient involves a post-translational modification in which EGFR-PTK-mediated tyrosine phosphorylation of the E1beta protein leads to enhanced ubiquitination followed by proteasome-mediated degradation. PMID: 17923481
    6. clinical findings are similar to those of PDHA1 deficiency, except that ataxia was more frequent in PDHA1 cases and consanguinity was found only in PDHB families. PMID: 18164639
    7. Species specificity in the interaction between hE1beta and hE2 in pyruvate dehydrogenase complex. PMID: 18206651

    顯示更多

    收起更多

  • 相關疾病:
    Pyruvate dehydrogenase E1-beta deficiency (PDHBD)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 數據庫鏈接:

    HGNC: 8808

    OMIM: 179060

    KEGG: hsa:5162

    STRING: 9606.ENSP00000307241

    UniGene: Hs.161357



主站蜘蛛池模板: 国产女人18毛片水真多1| 国产毛多水多高潮高清| 国产成人免费ā片在线观看| 国产xxxx视频在线| 亚洲综合精品伊人久久| 日日橹狠狠爱欧美视频| 成人看片黄a免费看| 国产又爽又大又黄a片| 国产香蕉尹人视频在线| 免费大黄网站在线观| 久久婷婷色香五月综合缴缴情| 亚洲欧美成人综合图区| 加勒比中文无码久久综合色| 无码播放一区二区三区| 男女作爱免费网站| 波多野结衣网站| 少妇高潮太爽了在线视| 男女久久久国产一区二区三区| 久久无码精品一区二区三区| 色噜噜狠狠色综合久夜色撩人| 精品无码人妻一区二区三区品| 黑人巨大无码中文字幕无码| 亚洲自偷自偷偷色无码中文 | 免费无码成人片| 午夜电影网va内射| 最近日本精品一卡2卡3卡4卡| 亚洲老妈激情一区二区三区| 中文字幕乱码人妻二区三区| 免费香蕉成视频人网站| 国产一本一道久久香蕉| 久久九九久精品国产免费直播| 欧美日韩精品一区二区三区不卡| 女人张开双腿让男人猛桶| 精品无码一区在线观看| 又嫩又硬又黄又爽的视频| 特大巨黑吊xxxx高潮| 九九精品成人免费国产片| 亚洲444kkkk在线观看| 午夜色大片在线观看| 国产xxx69麻豆国语对白| 国产女人爽的流水毛片|