在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PDHB Antibody

  • 中文名稱:
    PDHB兔多克隆抗體
  • 貨號:
    CSB-PA017717ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA017717ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA017717ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PDHB Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    DKFZp564K0164 antibody; mitochondrial antibody; ODPB_HUMAN antibody; pdhB antibody; PDHBD antibody; PDHE1 B antibody; PDHE1-B antibody; PHE1B antibody; Pyruvate dehydrogenase (lipoamide) beta antibody; Pyruvate dehydrogenase E1 beta polypeptide antibody; Pyruvate dehydrogenase E1 component subunit beta antibody; Pyruvate dehydrogenase E1 component subunit beta mitochondrial antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Pyruvate dehydrogenase E1 component subunit beta, mitochondrial protein (1-300AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
  • 基因功能參考文獻:
    1. PDHB was downregulated in nasopharyngeal carcinoma cells. Forced expression of PDHB in NPC cells inhibited cell growth and migration, while knocking down the expression of PDHB promoted the growth, migration, and tumorigenesis of NPC cells. PDHB inhibited ERK signaling and cell growth driven by RasV12. PMID: 26857147
    2. Data indicate that (pro)renin receptor ATP6PA2 interacts with the E1 beta subunit of pyruvate dehydrogenase and controlling its protein stability PMID: 25720494
    3. PHD3 depletion did not affect the expression of the PDH-E1alpha, E1beta, and E2 subunits, or the phosphorylation status of E1alpha, but destabilized the PDH complex (PDC), resulting in less functional PDC. PMID: 25088999
    4. Sequencing of PDHB reveals a homozygous point mutation (c.302T>C), causing a predicted amino acid change in patient 1. Patient 2 is compound heterozygote for mutations c.301A>G (p.M101V) and c.313G>A (p.R105Q). PMID: 19924563
    5. Data indicate that PDH deficiency in our patient involves a post-translational modification in which EGFR-PTK-mediated tyrosine phosphorylation of the E1beta protein leads to enhanced ubiquitination followed by proteasome-mediated degradation. PMID: 17923481
    6. clinical findings are similar to those of PDHA1 deficiency, except that ataxia was more frequent in PDHA1 cases and consanguinity was found only in PDHB families. PMID: 18164639
    7. Species specificity in the interaction between hE1beta and hE2 in pyruvate dehydrogenase complex. PMID: 18206651

    顯示更多

    收起更多

  • 相關疾病:
    Pyruvate dehydrogenase E1-beta deficiency (PDHBD)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 數據庫鏈接:

    HGNC: 8808

    OMIM: 179060

    KEGG: hsa:5162

    STRING: 9606.ENSP00000307241

    UniGene: Hs.161357



主站蜘蛛池模板: 欧洲吸奶大片在线看| 日韩av高清在线观看| 无套内射视频囯产| 精品国产无套在线观看| 国产午夜理论片不卡| 久久亚洲国产精品影院| 成 人 网 站不卡在线观看| 国产成人无码短视频| 国产精品久久久午夜夜伦鲁鲁| 老熟女重囗味hdxx69| 先锋影音xfyy5566男人资源| 欧美韩中文精品有码视频在线| 日本成熟少妇喷浆视频| 国产在线一区二区香蕉 在线| 欧美人与性动交ccoo| 国产农村妇女精品一二区| 亚洲欧洲∨国产一区二区三区| 精品服丝袜无码视频一区| 人人妻人人超人人| 人妻在卧室被老板疯狂进入| 免费的黄网站在线观看| 日本三级吃奶头添泬| 国产欧美日韩另类在线专区| 中文字幕制服丝袜第57页| 妺妺窝人体色www看人体| 好湿好紧太硬了我太爽了视频| 超碰香蕉人人网99精品| 日日摸日日碰夜夜爽免费| 成人做受120秒试看试看视频| 国产午夜福利精品久久2021| 日本内射精品一区二区视频| 中文字幕人妻被公上司喝醉在线 | 少妇人妻无码专区毛片| 精品1卡二卡三卡四卡老狼| 免费国产黄网站在线观看动图| 国产女人与公拘交在线播放| 日本成熟少妇喷浆视频| 亚洲人成网线在线播放va蜜芽| 97久久精品无码一区二区| 亚洲色无码专区在线播放| 色综合亚洲一区二区小说性色aⅴ|