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  4. HSPA12A Recombinant Monoclonal Antibody

HSPA12A Recombinant Monoclonal Antibody

  • 中文名稱：
    HSPA12A Recombinant Monoclonal Antibody
  • 貨號(hào)：
    CSB-RA846891A0HU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • Immunocytochemical staining of C2C12 cells with HSPA12A antibody . Nuclei were stained blue with DAPI; HSPA12A was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Low. Scale bar, 20 μm.
    • Western blotting analysis using HSPA12A antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with HSPA12A antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    HSPA12A
  • 別名：
    HSPA12A; Heat Shock Protein Family A (Hsp70) Member 12A; KIAA0417; Heat Shock 70 KDa Protein 12A; Heat Shock 70kDa Protein 12A; Heat Shock 70kD Protein 12A; FLJ13874
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human HSPA12A protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號(hào)：
    6H12
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    ICC 1:100-1:1000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization.
  • 基因功能參考文獻(xiàn)：
    1. The genotype "A/G" of rs1665650 in HSPA12A gene was associated with a decreased risk of gastric cancer. PMID: 26302849
    2. High BCLC staging scores, advanced cirrhosis and the overexpression of HSPA12A and HSP90B1 might be associated with poor survival from HCC, whereas high levels of HSPA4, HSPA5 and HSPA6 might be associated with earlier recurrence of HCC PMID: 25798051
    3. We found that HSPA12A is expressed in the human brain and shows a neuron- and region-specific transcript distribution, with strongest expression in the frontal and occipital cortical regions. HSPA12A Mrna was significantly reduced in schizophrenia. PMID: 15601604
    4. Observational study of gene-disease association. (HuGE Navigator) PMID: 17601350
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 18977241

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  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Heat shock protein 70 family
  • 組織特異性：
    Widely expressed with highest levels in brain, kidney and muscle.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 19022

    OMIM: 610701

    KEGG: hsa:259217

    STRING: 9606.ENSP00000358211

    UniGene: Hs.648448



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