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  4. HSPA12A Antibody

HSPA12A Antibody

  • 中文名稱：
    HSPA12A兔多克隆抗體
  • 貨號：
    CSB-PA010817LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: SH-SY5Y whole cell lysate, 293 whole cell lysate, HepG2 whole cell lysate
      All lanes: HSPA12A antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 75 kDa
      Observed band size: 75 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HSPA12A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HSPA12A
  • 別名：
    FLJ13874 antibody; Heat shock 70 kDa protein 12A antibody; heat shock 70kD protein 12A antibody; heat shock 70kDa protein 12A antibody; HS12A_HUMAN antibody; Hspa12a antibody; KIAA0417 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Heat shock 70 kDa protein 12A protein (2-231AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，HSPA12A Antibody (CSB-PA010817LA01HU)，的標記方式是Non-conjugated。對于HSPA12A Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA010817LB01HU HSPA12A Antibody, HRP conjugated ELISA
    FITC CSB-PA010817LC01HU HSPA12A Antibody, FITC conjugated
    Biotin CSB-PA010817LD01HU HSPA12A Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization.
  • 基因功能參考文獻：
    1. The genotype "A/G" of rs1665650 in HSPA12A gene was associated with a decreased risk of gastric cancer. PMID: 26302849
    2. High BCLC staging scores, advanced cirrhosis and the overexpression of HSPA12A and HSP90B1 might be associated with poor survival from HCC, whereas high levels of HSPA4, HSPA5 and HSPA6 might be associated with earlier recurrence of HCC PMID: 25798051
    3. We found that HSPA12A is expressed in the human brain and shows a neuron- and region-specific transcript distribution, with strongest expression in the frontal and occipital cortical regions. HSPA12A Mrna was significantly reduced in schizophrenia. PMID: 15601604
    4. Observational study of gene-disease association. (HuGE Navigator) PMID: 17601350
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 18977241

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  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Heat shock protein 70 family
  • 組織特異性：
    Widely expressed with highest levels in brain, kidney and muscle.
  • 數據庫鏈接：

    HGNC: 19022

    OMIM: 610701

    KEGG: hsa:259217

    STRING: 9606.ENSP00000358211

    UniGene: Hs.648448



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