在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 重組抗體
  4. FILIP1L Recombinant Monoclonal Antibody

FILIP1L Recombinant Monoclonal Antibody

  • 中文名稱：
    FILIP1L Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA679703MA1HU
  • 規格：
    ￥1320
  • 圖片：
    • IHC image of CSB-RA679703MA1HU diluted at 1：100 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    FILIP1L
  • 別名：
    130 kDa GPBP-interacting protein antibody; 90 kDa GPBP-interacting protein antibody; COL4A3BPIP antibody; DOC-1 antibody; DOC1 antibody; Downregulated in ovarian cancer 1 81 kDa isoform antibody; FIL1L_HUMAN antibody; Filamin A-interacting protein 1-like antibody; FILIP1L antibody; GIP130 antibody; GIP130a antibody; GIP130b antibody; GIP130c antibody; GIP90 antibody; GPBP interacting protein 90 antibody; Protein down-regulated in ovarian cancer 1 antibody
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human FILIP1L protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    hIgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    4H7G5
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.
  • 基因功能參考文獻：
    1. FILIP1L inhibits progression in colorectal cancer by inhibiting tumor cell proliferation and angiogenesis. PMID: 27750216
    2. Studies have shown that FILIP1L expression is related with inhibition of metastases and chemoresistance of ovarian neoplasm, which is associated with downregulation of EMT through beta-catenin degradation. FILIP1L expression correlates with significantly improved overall survival. PMID: 27776341
    3. these findings suggest that FILIP1L reduces beta-catenin levels, which may lead to the transcriptional downregulation of WNT target genes such as MMPs, resulting in inhibition of metastasis PMID: 24327474
    4. down-regulation of FILIP1L associated with DNA methylation is related with the invasive phenotype in various cancers. PMID: 24340050
    5. these findings suggest that downregulation of FILIP1L associated with DNA methylation is related with the invasive phenotype in ovarian cancer and that modulation of FILIP1L expression has the potential to be a target for ovarian cancer therapy. PMID: 21693594
    6. a novel function for FILIP-1L and a pathway for Hsf1 degradation through the ubiquitin-proteasome system. PMID: 21784850
    7. DOC1 might play a role in mediating some of the effects of EMAP-II on endothelial cells PMID: 15935955

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Membrane. Nucleus.
  • 蛋白家族：
    FILIP1 family
  • 組織特異性：
    Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. D
  • 數據庫鏈接：

    HGNC: 24589

    OMIM: 612993

    KEGG: hsa:11259

    STRING: 9606.ENSP00000346560

    UniGene: Hs.104672



主站蜘蛛池模板： 97国产精东麻豆人妻电影| 亚洲无线卡一卡二| 激情无码人妻又粗又大| 无码专区aaaaaa免费视频| 日产一区日产2区| 国产乱子伦三级在线播放| 午夜性色吃奶添下面69影院| a在线观看免费网站大全| 欧美人与动牲交a精品| 成人免费看吃奶视频网站| 香蕉精品亚洲二区在线观看| 学生妹无套内射正在播放| 亚洲精品无码鲁网中文电影| 精品国产亚洲一区二区三区| 亚洲爆乳无码一区二区三区| 蜜臀av色欲a片无人一区| 亚洲综合日韩av无码毛片| 人妻互换免费中文字幕| 色一情一区二| 少妇被又大又粗猛烈进出视频| 欧美交换国产一区内射| 国产精品99久久精品爆乳| 在线观看麻豆国产成人av在线播放| 亚洲综合网站久久久| 国产精品无码av在线播放| 免费三级现频在线观看免费 | 人妻熟妇乱又伦精品视频中文字幕| 中文乱码免费一区二区| 无码专区手机在线播放| 欧美又粗又大aaa片| 国产日产欧洲无码视频| 人人狠狠久久亚洲综合88| 精品久久久久久中文字幕大豆网| 午夜免费啪视频| 国产成人精品日本亚洲一区| 亚洲成年看片在线观看| 国产成人av一区二区三区在线观看| 97午夜理论片在线影院| 日韩美女自卫慰黄网站| 精品一区二区三区在线观看| 久久国产劲爆∧v内射|