在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FILIP1L Antibody, HRP conjugated

  • 中文名稱:
    FILIP1L兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA679703LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) FILIP1L Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    FILIP1L
  • 別名:
    130 kDa GPBP-interacting protein antibody; 90 kDa GPBP-interacting protein antibody; COL4A3BPIP antibody; DOC-1 antibody; DOC1 antibody; Downregulated in ovarian cancer 1 81 kDa isoform antibody; FIL1L_HUMAN antibody; Filamin A-interacting protein 1-like antibody; FILIP1L antibody; GIP130 antibody; GIP130a antibody; GIP130b antibody; GIP130c antibody; GIP90 antibody; GPBP interacting protein 90 antibody; Protein down-regulated in ovarian cancer 1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Filamin A-interacting protein 1-like protein (1-200AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.
  • 基因功能參考文獻(xiàn):
    1. FILIP1L inhibits progression in colorectal cancer by inhibiting tumor cell proliferation and angiogenesis. PMID: 27750216
    2. Studies have shown that FILIP1L expression is related with inhibition of metastases and chemoresistance of ovarian neoplasm, which is associated with downregulation of EMT through beta-catenin degradation. FILIP1L expression correlates with significantly improved overall survival. PMID: 27776341
    3. these findings suggest that FILIP1L reduces beta-catenin levels, which may lead to the transcriptional downregulation of WNT target genes such as MMPs, resulting in inhibition of metastasis PMID: 24327474
    4. down-regulation of FILIP1L associated with DNA methylation is related with the invasive phenotype in various cancers. PMID: 24340050
    5. these findings suggest that downregulation of FILIP1L associated with DNA methylation is related with the invasive phenotype in ovarian cancer and that modulation of FILIP1L expression has the potential to be a target for ovarian cancer therapy. PMID: 21693594
    6. a novel function for FILIP-1L and a pathway for Hsf1 degradation through the ubiquitin-proteasome system. PMID: 21784850
    7. DOC1 might play a role in mediating some of the effects of EMAP-II on endothelial cells PMID: 15935955

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Membrane. Nucleus.
  • 蛋白家族:
    FILIP1 family
  • 組織特異性:
    Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. D
  • 數(shù)據(jù)庫鏈接:

    HGNC: 24589

    OMIM: 612993

    KEGG: hsa:11259

    STRING: 9606.ENSP00000346560

    UniGene: Hs.104672



主站蜘蛛池模板: av无码国产在线观看岛国| 真实的国产乱xxxx在线| 无码一区二区三区在线观看| 亚洲va无码va在线va天堂| 男女啪啪抽搐高潮动态图| 18禁超污无遮挡无码免费动态图 | 国产精品永久久久久久久久久| www国产精品内射熟女| 日韩在线一区二区三区免费视频| 免费人成在线视频无码| 亚洲另类激情专区小说| 成人国产亚洲精品a区天堂| 激情综合色综合久久综合| 亚洲youwu永久无码精品| 亚洲精品久久久久一区二区三区| 狂野欧美性猛交xxxx| 男人扒开女人内裤强吻桶进去 | 国产果冻豆传媒麻婆精东| 无码人妻一区二区三区免费手机| 波多野结衣av无码| 饥渴少妇做私密保健视频| 午夜精品久久久久9999| 午夜精品影视国产一区在线麻豆| 中国少妇内射xxxx狠干| 国产成a人亚洲精v品无码 | 狼人大香伊蕉国产www亚洲| 台湾无码av一区二区三区| 日本一区午夜艳熟免费| 国内露脸中年夫妇交换| 2021国产精品视频网站| 日韩在线 | 中文| 久久久久99精品国产片| 国内少妇偷人精品免费| 97成人精品区在线播放| 一道本在线伊人蕉无码| 国产96在线 | 欧美| 18禁亚洲深夜福利入口| 色八区人妻在线视频免费| 日韩av无码精品人妻系列| 婷婷丁香六月激情综合在线人| 国产美女精品中文网蜜芽宝贝|