在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

tgfb1 Antibody, HRP conjugated

  • 中文名稱:
    tgfb1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA023446LB01OEI
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Oncorhynchus mykiss tgfb1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    tgfb1 antibody; Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide antibody; LAP); Transforming growth factor beta-1 antibody; TGF-beta-1)] antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Oncorhynchus mykiss
  • 免疫原:
    Recombinant Oncorhynchus mykiss Transforming growth factor beta-1 proprotein protein (271-382AA)
  • 免疫原種屬:
    Oncorhynchus mykiss
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.; Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1.; Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration. Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains remain non-covalently linked rendering TGF-beta-1 inactive during storage in extracellular matrix. At the same time, LAP chain interacts with 'milieu molecules', such as ltbp1, lrrc32/garp and lrrc33/nrros that control activation of TGF-beta-1 and maintain it in a latent state during storage in extracellular milieus. TGF-beta-1 is released from LAP by integrins (ITGAV:ITGB6 or ITGAV:ITGB8): integrin-binding to LAP stabilizes an alternative conformation of the LAP bowtie tail and results in distortion of the LAP chain and subsequent release of the active TGF-beta-1. Once activated following release of LAP, TGF-beta-1 acts by binding to TGF-beta receptors (tgfbr1 and tgfbr2), which transduce signal. While expressed by many cells types, TGF-beta-1 only has a very localized range of action within cell environment thanks to fine regulation of its activation by Latency-associated peptide chain (LAP) and 'milieu molecules'. Plays an important role in bone remodeling: acts as a potent stimulator of osteoblastic bone formation. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. Can induce epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types.
  • 亞細胞定位:
    [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix.; [Transforming growth factor beta-1]: Secreted.
  • 蛋白家族:
    TGF-beta family
  • 組織特異性:
    Expressed in blood leukocytes, kidney macrophages, brain, gill and spleen but not in liver.
  • 數據庫鏈接:

    UniGene: Omy.30069



主站蜘蛛池模板: 97se狼狼狼狼狼亚洲网| 苍井空浴缸大战猛男120分钟| 性做久久久久久免费观看| 日本妇人成熟免费| 国产黑色丝袜在线观看下| 日本亚洲欧美日韩国产ay| 亚洲国内成人精品网| 中文乱码免费一区二区三区 | 亚洲中文字幕久久精品无码va| 人人妻人人澡人人爽欧美精品| 亚洲国产精品无码久久久不卡| 99re久久精品国产| 欧美性猛交xxxx富婆| 国产午夜精品一区二区三区漫画| 日本亚洲欧美综合在线| 夜夜高潮夜夜爽夜夜爱| 老湿机69福利区无码| 精品偷拍被偷拍在线观看| 日韩欧美国产一区精品| 国产一区二区三区不卡在线观看| 亚洲国产成人久久综合一区| 久久婷婷色香五月综合缴缴情| 人妻少妇精品视中文字幕国语| 久久99精品九九九久久婷婷| 国产精品18久久久久久麻辣| 亚洲 日韩 国产 中文有码| 久久久久久成人综合网| 久久国产亚洲高清观看| 久久综合伊人77777麻豆| 久久精品久久电影免费理论片 | 国产精品成人一区二区不卡| 一区二区三区av高清免费波多| 久久综合给合久久狠狠狠97色| 97午夜理论片在线影院| 久久国产精品99久久久久久口爆| 国产性色av一区二区三区| 一本大道熟女人妻中文字幕在线| 精品久久久久久久久中文字幕| 2020最新无码国产在线观看| 人妻无码中文专区久久五月婷| 无码av一区二区三区无码|