在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

tgfb1 Antibody, Biotin conjugated

  • 中文名稱:
    tgfb1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA023446LD01OEI
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Oncorhynchus mykiss tgfb1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    tgfb1 antibody; Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide antibody; LAP); Transforming growth factor beta-1 antibody; TGF-beta-1)] antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Oncorhynchus mykiss
  • 免疫原:
    Recombinant Oncorhynchus mykiss Transforming growth factor beta-1 proprotein protein (271-382AA)
  • 免疫原種屬:
    Oncorhynchus mykiss
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.; Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1.; Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration. Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains remain non-covalently linked rendering TGF-beta-1 inactive during storage in extracellular matrix. At the same time, LAP chain interacts with 'milieu molecules', such as ltbp1, lrrc32/garp and lrrc33/nrros that control activation of TGF-beta-1 and maintain it in a latent state during storage in extracellular milieus. TGF-beta-1 is released from LAP by integrins (ITGAV:ITGB6 or ITGAV:ITGB8): integrin-binding to LAP stabilizes an alternative conformation of the LAP bowtie tail and results in distortion of the LAP chain and subsequent release of the active TGF-beta-1. Once activated following release of LAP, TGF-beta-1 acts by binding to TGF-beta receptors (tgfbr1 and tgfbr2), which transduce signal. While expressed by many cells types, TGF-beta-1 only has a very localized range of action within cell environment thanks to fine regulation of its activation by Latency-associated peptide chain (LAP) and 'milieu molecules'. Plays an important role in bone remodeling: acts as a potent stimulator of osteoblastic bone formation. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. Can induce epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types.
  • 亞細(xì)胞定位:
    [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix.; [Transforming growth factor beta-1]: Secreted.
  • 蛋白家族:
    TGF-beta family
  • 組織特異性:
    Expressed in blood leukocytes, kidney macrophages, brain, gill and spleen but not in liver.
  • 數(shù)據(jù)庫(kù)鏈接:

    UniGene: Omy.30069



主站蜘蛛池模板: 人人妻人人澡人人爽欧美精品| 国产精品亚洲综合一区在线观看| 人妻少妇精品专区性色av| 极品少妇被猛得白浆直喷白浆小说| 美女又色又爽视频免费| 久在线观看福利视频| 亚欧无线一线二线三线区别| 理论片午午伦夜理片影院| 亚洲国产欧美在线人成aaaa| 成人精品视频99在线观看免费| 美女张开腿黄网站免费下载| 国产成+人+综合+亚洲专区| 巨乳美乳一区二区三区| 一本色道久久综合无码人妻| 男人扒开女人双腿猛进视频| 国产免费爽爽视频在线观看| 国产精品无码一区二区在线观一| 亚洲欧美精品aaaaaa片| 国产丝袜足j在线视频播放| 2019精品国自产拍在线不卡| 少妇伦子伦精品无吗| 中文在线最新版天堂| 浪荡女天天不停挨cao日常视频| 亚洲va中文字幕无码一二三区| 性欧美vr高清极品| 国产真实伦对白全集| 男女啪啪抽搐呻吟高潮动态图| 精品人妻无码区二区三区| 婷婷久久综合九色综合88| 天无日天天射天天视| av性色在线乱叫| 亚洲国产成人精品女人久久久| 国产成人综合久久三区| 亚洲综合天堂一区二区三区| 亚洲精品乱码久久久久久v| 女人被狂躁c到高潮| 99久久免费国产精品四虎| 天堂中文官网在线| 亚洲精品一区二区三区蜜臀| 波多野结衣爽到高潮大喷| 国产免费极品av吧在线观看|