在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. gag Antibody, HRP conjugated

gag Antibody, HRP conjugated

Rare Species
  • 中文名稱：
    gag兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA356017DB01MHK
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Moloney murine leukemia virus gag Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    gag antibody; Gag polyprotein antibody; Pr65gag antibody; Core polyprotein) [Cleaved into: Matrix protein p15 antibody; MA); RNA-binding phosphoprotein p12 antibody; pp12); Capsid protein p30 antibody; CA); Nucleocapsid protein p10-Gag antibody; NC-gag)] antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Moloney murine leukemia virus
  • 免疫原：
    Recombinant Moloney murine leukemia virus Gag polyprotein protein (216-478AA)
  • 免疫原種屬：
    Moloney murine leukemia virus
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably links the viral protein to the host ESCRT pathway and facilitates release.; Targets Gag and gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the pre-integration complex.; Constituent of the pre-integration complex (PIC) which tethers the latter to mitotic chromosomes.; Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.; Involved in the packaging and encapsidation of two copies of the genome. Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5'-end of the genome. This binding is dependent on genome dimerization.
  • 基因功能參考文獻(xiàn)：
    1. The structure of the minimal sequence of the murine leukemia virus p12 protein necessary for the host chromatin binding was elucidated. PMID: 27707926
    2. Phosphorylation requirement of murine leukemia virus p12 virus p12 protein necessary for the host chromatin binding was elucidated. PMID: 27707931
    3. The N-terminal intracellular domain of the glycoGag is responsible for its effect on HIV-1 infectivity. PMID: 24403584
    4. Authors found that mature Gag proteins MA and TM were bound to the immature core consisting of the Gag polyprotein (PrGag) and viral RNA (vRNA). PMID: 23643491
    5. in presence of nucleocapsid (NC) chaperone, RNA dimerization occurred rapidly through a single structural intermediate; NC interacted primarily with guanosine residues; results show RNA chaperones can simplify RNA folding landscapes by weakening intramolecular interactions involving guanosine PMID: 23470731
    6. selective packaging of dimeric RNA is explained by the nucleic acid binding domain derived from Gag binding within the virus to the sequence UCUG-UR-UCUG PMID: 20974908
    7. results suggest a cooperative effect of p12 and capsid during the early events of MLV replication PMID: 15767417
    8. interaction of Gag with Tsg101 and Alix favors budding from the plasma membrane and relieves a requirement for ubiquitination by Nedd4 PMID: 15908698
    9. results indicate that glycosylated gag protein is important for M-MuLV replication in vivo and in vitro and that the protein may be involved in a late step in viral budding or release PMID: 17267509
    10. Abl protein contribute to proper localization by playing a dominant role in trafficking of the v-Abl molecule PMID: 18367522
    11. Basal budding and replication of the murine leukemia virus are independent of the gag L domains PMID: 18667521

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    [Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor. Host late endosome membrane; Lipid-anchor. Host endosome, host multivesicular body.; [Matrix protein p15]: Virion.; [Capsid protein p30]: Virion.; [Nucleocapsid protein p10-Gag]: Virion.; [RNA-binding phosphoprotein p12]: Host cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    KEGG: vg:1491870



主站蜘蛛池模板： 无码中文字幕波多野结衣 | 国产高清在线精品二区| 久久综合给合久久狠狠狠97色| 2018国产精华国产精品| 免费人成网站在线观看欧美| 久久久久影院美女国产主播| 牲交欧美兽交欧美| 丰满人妻熟妇乱又伦精品软件| 日本一区二区三区免费更新不卡 | 四川老熟女下面又黑又肥| 亚洲精品无码国产| 久久精品第九区免费观看| 欧美牲交a欧美牲交aⅴ一| 久久综合给合久久狠狠狠97色69 | 日韩精品一卡2卡三卡4卡| 日本高清中文字幕免费一区二区| 国产亚洲综合欧美一区二区| 婷婷四房播播| 久艹视频免费看| 黑人巨大白妞出浆| 丰满少妇熟乱xxxxx视频| 亚洲日韩av无码一区二区三区 | 亚洲国产精品自在拍在线播放蜜臀| 国产乱沈阳女人高潮乱叫老 | 国产真实露脸乱子伦原著 | 草草网站影院白丝内射| 国产午夜亚洲精品国产成人小说 | 成人毛片100部免费看| 国产大屁股视频免费区| 中国少妇内射xxxhd| 成人性做爰aaa片免费看曹查理| 久久99国产综合精品免费| 久久综合久久88中字幕文| 中文字幕av无码专区第一页| 国产精品高清一区二区三区| 国产女人精品视频国产灰线| 曰的好深好爽免费视频网站| 影音先锋中文字幕人妻| 精品国产免费一区二区三区香蕉| 日日噜噜大屁股熟妇| 亚洲色精品三区二区一区|