在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. gag Antibody, FITC conjugated

gag Antibody, FITC conjugated

Rare Species
  • 中文名稱：
    gag兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA356017DC01MHK
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Moloney murine leukemia virus gag Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    gag antibody; Gag polyprotein antibody; Pr65gag antibody; Core polyprotein) [Cleaved into: Matrix protein p15 antibody; MA); RNA-binding phosphoprotein p12 antibody; pp12); Capsid protein p30 antibody; CA); Nucleocapsid protein p10-Gag antibody; NC-gag)] antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Moloney murine leukemia virus
  • 免疫原：
    Recombinant Moloney murine leukemia virus Gag polyprotein protein (216-478AA)
  • 免疫原種屬：
    Moloney murine leukemia virus
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably links the viral protein to the host ESCRT pathway and facilitates release.; Targets Gag and gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the pre-integration complex.; Constituent of the pre-integration complex (PIC) which tethers the latter to mitotic chromosomes.; Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.; Involved in the packaging and encapsidation of two copies of the genome. Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5'-end of the genome. This binding is dependent on genome dimerization.
  • 基因功能參考文獻：
    1. The structure of the minimal sequence of the murine leukemia virus p12 protein necessary for the host chromatin binding was elucidated. PMID: 27707926
    2. Phosphorylation requirement of murine leukemia virus p12 virus p12 protein necessary for the host chromatin binding was elucidated. PMID: 27707931
    3. The N-terminal intracellular domain of the glycoGag is responsible for its effect on HIV-1 infectivity. PMID: 24403584
    4. Authors found that mature Gag proteins MA and TM were bound to the immature core consisting of the Gag polyprotein (PrGag) and viral RNA (vRNA). PMID: 23643491
    5. in presence of nucleocapsid (NC) chaperone, RNA dimerization occurred rapidly through a single structural intermediate; NC interacted primarily with guanosine residues; results show RNA chaperones can simplify RNA folding landscapes by weakening intramolecular interactions involving guanosine PMID: 23470731
    6. selective packaging of dimeric RNA is explained by the nucleic acid binding domain derived from Gag binding within the virus to the sequence UCUG-UR-UCUG PMID: 20974908
    7. results suggest a cooperative effect of p12 and capsid during the early events of MLV replication PMID: 15767417
    8. interaction of Gag with Tsg101 and Alix favors budding from the plasma membrane and relieves a requirement for ubiquitination by Nedd4 PMID: 15908698
    9. results indicate that glycosylated gag protein is important for M-MuLV replication in vivo and in vitro and that the protein may be involved in a late step in viral budding or release PMID: 17267509
    10. Abl protein contribute to proper localization by playing a dominant role in trafficking of the v-Abl molecule PMID: 18367522
    11. Basal budding and replication of the murine leukemia virus are independent of the gag L domains PMID: 18667521

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    [Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor. Host late endosome membrane; Lipid-anchor. Host endosome, host multivesicular body.; [Matrix protein p15]: Virion.; [Capsid protein p30]: Virion.; [Nucleocapsid protein p10-Gag]: Virion.; [RNA-binding phosphoprotein p12]: Host cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    KEGG: vg:1491870



主站蜘蛛池模板： 性一交一黄一片| 国产成人精品999视频| 97在线观看播放| 成人天堂资源www在线| 欧美一区二区三区视频在线观看| 国精品午夜福利视频| 国产乱码一区二区三区爽爽爽| 久久综合香蕉国产蜜臀av| 免费观看全黄做爰的视频| 野外少妇被弄到喷水在线观看| 无码一卡二卡三卡四卡| 亚洲熟妇丰满多毛xxxx| 亚洲性无码av在线欣赏网| 久久亚洲精品情侣| 亚洲欧美综合精品二区| 搡女人真爽免费视频大全| 亚洲国产精品一区第二页| 国产在线看片免费观看| 正在播放国产乱子伦最新视频 | 最美女人体内射精一区二区| 99精品国产成人一区二区| 澳门永久av免费网站| 色情无码一区二区三区| 秋霞无码久久久精品交换| 99亚洲乱人伦aⅴ精品| 奇米影视888欧美在线观看| 99久久久无码国产精品动漫| 中文字幕 乱码 中文乱码视频| 99国产精品久久99久久久| av人摸人人人澡人人超碰小说| 97国语精品自产拍在线观看| 中文字幕日韩人妻无码| 国产韩国精品一区二区三区久久| 无码h肉在线观看免费一区| 亚洲国产成人久久综合碰碰| 中文精品久久久久人妻不卡| 人人超碰人摸人爱| 国产午精品午夜福利757视频播放 麻豆专媒体一区二区 | 久久久欧美精品激情| 亚洲熟妇丰满xxxxx| 国内精品久久毛片一区二区 |