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ZNF300 Antibody, Biotin conjugated

  • 中文名稱:
    ZNF300兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA026653LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ZNF300 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ZNF300
  • 別名:
    DKFZp686B24204 antibody; Kruppel like zinc finger protein antibody; OTTHUMP00000160554 antibody; OTTHUMP00000206798 antibody; Zinc finger protein 300 antibody; ZN300_HUMAN antibody; ZNF300 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Zinc finger protein 300 protein (1-300AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Has a transcriptional repressor activity.
  • 基因功能參考文獻:
    1. Our findings further support ZNF300P1 as frequently methylated in ovarian cancer and reveal a novel function for ZNF300P1 lincRNA expression PMID: 24393131
    2. A novel function for ZNF300 in tumour development was identified that may uniquely link inflammation and NF-kappa B to tumourigenesis in humans but not in mice. PMID: 21777376
    3. Data show that co-expression of ZNF300 and Egr1 lead to enhanced IL-2Rbeta promoter activity, and suggest that ZNF300 is another regulator of the human IL-2Rbeta promoter. PMID: 20585888
    4. ZNF300 was activated by PU.1 and suggested that the regulation may be involved in the progression of leukemia development and hematopoietic differentiation. PMID: 20471086
    5. ZNF-300 and novel splice variant ZNF300-B are both expressed highly in human testis. PMID: 17541838
    6. Results show that the ZNF300 gene encodes a 68-kDa nuclear protein that binds DNA in a sequence-specific manner. PMID: 18350257

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  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Krueppel C2H2-type zinc-finger protein family
  • 組織特異性:
    Expressed mostly in heart, skeletal muscle and brain. Isoform 1 and isoform 2 are highly expressed in testis.
  • 數據庫鏈接:

    HGNC: 13091

    OMIM: 612429

    KEGG: hsa:91975

    STRING: 9606.ENSP00000397178

    UniGene: Hs.134885



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