在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ZMAT3 Antibody

  • 中文名稱:
    ZMAT3兔多克隆抗體
  • 貨號:
    CSB-PA026499GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    FLJ12296 antibody; FLJ31683 antibody; MGC10613 antibody; OTTHUMP00000211906 antibody; OTTHUMP00000211907 antibody; p53 activated gene 608 antibody; p53 inducible zinc finger protein antibody; p53 target zinc finger protein antibody; p53-activated gene 608 protein antibody; PAG 608 antibody; WIG 1 antibody; WIG 1/PAG608 protein antibody; WIG1 antibody; WIG1/PAG608 protein antibody; Wildtype p53-induced gene antibody; Zinc finger matrin type 3 antibody; Zinc finger matrin-type protein 3 antibody; Zinc finger protein WIG 1 antibody; Zinc finger protein WIG-1 antibody; Zinc finger protein WIG1 antibody; ZMAT 3 antibody; Zmat3 antibody; ZMAT3_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ZMAT3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus.
  • 基因功能參考文獻:
    1. WIG1 governs the miRNA-dependent and the miRNA-independent recruitment of AGO2 to lower the stability of and suppress the translation of ACOT7 mRNA. PMID: 28472401
    2. we propose that Wig1, a key p53 downstream molecule in HD condition, play an important role in stabilizing mutant Htt mRNA and thereby accelerating HD pathology in the mHtt-p53-Wig1 positive feedback manner PMID: 27206983
    3. expression of the p53 target Wig-1 is associated with HPV status and patient survival in cervical carcinoma PMID: 25379706
    4. Results suggest a role of Wig-1 as a survival factor that directs the p53 stress response toward cell cycle arrest rather than apoptosis through the regulation of FAS and 14-3-3sigma mRNA levels. PMID: 24469038
    5. PSF and MATR3 are cellular host factors that bind viral RNA and promote Rev activity. PMID: 23158102
    6. The data indicated a novel role for Wig1 in RNA-induced silencing complex target accessibility, which is a key step in RNA-mediated gene silencing. Fine tuning of p21 levels by Wig1 was essential for the prevention of cellular senescence. PMID: 23085987
    7. Wig-1 knockdown causes a dramatic inhibition of N-Myc expression and triggers differentiation in neuroblastoma cells carrying amplified N-Myc. PMID: 22513872
    8. WIG-1 might be involved in the zinc-induced cell cycle arrest and apoptosis of human esophageal squamous cell carcinoma cells PMID: 21559779
    9. WIG-1 might be a novel modifier in esophageal carcinogenesis, and the WIG-1 MAb should be useful in further study of the mechanism in WIG-1-related physiological reactions. PMID: 21050045
    10. The cellular distribution of the nuclear matrix protein matrin 3 is altered by novel phosphorylation induced by the alphaherpesvirus US3 kinase family. PMID: 20962082
    11. Results demonstrate that human Wig-1 can bind different types of double-stranded RNAs (dsRNAs), including dsRNAs resembling small interfering RNAs and microRNAs, and indicate that dsRNA binding has a role in Wig-1-mediated regulation of cell growth. PMID: 16844115
    12. Wig-1-binding proteins, hnRNP A2/B1 and RNA Helicase A, both of which are involved in RNA processing, were identified. PMID: 18519039
    13. Data demonstrated a direct interaction between Dicer and Wig-1 and both may play a common role in dsRNA-related gene regulation. PMID: 19127773
    14. the p53 target Wig-1 is a previously undescribed AU-rich element-regulating protein that acts as a positive feedback regulator of p53, with implications both for the steady-state levels of p53 and for the p53 stress response PMID: 19805223

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Nucleus, nucleolus.
  • 組織特異性:
    Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine.
  • 數據庫鏈接:

    HGNC: 29983

    OMIM: 606452

    KEGG: hsa:64393

    STRING: 9606.ENSP00000311221

    UniGene: Hs.371609



主站蜘蛛池模板: 无尺码精品产品国产| 99久久久无码国产精品古装| 婷婷丁香五月六月综合激情啪| 亚洲精品你懂的在线观看| 忘忧草影院在线www韩国日本| 97在线观看播放| 午夜理理伦电影a片无码| 色综合色综合久久综合频道88| 午夜a理论片在线播放| 亚洲日本va中文字幕人妖| 朝鲜女人大白屁股ass孕交| 天天天欲色欲色www免费| 免费国产h视频在线观看| 人妻少妇无码专视频在线| 国产偷窥熟女精品视频大全| 日韩欧美人妻一区二区三区| 在厨房拨开内裤进入在线视频| 国产精品久久久久久爽爽爽床戏| 久久久橹橹橹久久久久| 国产精品美女久久久| 久久影院午夜理论片无码| 国产又爽又黄又刺激的视频| 久久久久麻豆v国产精华液好用吗| 大地资源在线播放观看mv| 99国产精品久久久蜜芽| 亚洲暴爽av人人爽日日碰| 免费观看日本污污ww网站| 隔壁邻居是巨爆乳寡妇| 国产黄网永久免费视频大全| 国产果冻豆传媒麻婆| 超薄肉色丝袜一区二区| 国产av无码专区国产乱码 | 免费的黄网站在线观看| 亚洲精品久久久一二三区| 亚洲国产av无码一区二区三区| 日韩成人大屁股内射喷水| 国产9 9在线 | 中文| yyyy11111少妇影院| 无码av永久免费专区麻豆| 国产日韩在线时看高清视频| 欧美 亚洲 国产 日韩 综aⅴ|