在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ZMAT3 Antibody

  • 中文名稱:
    ZMAT3兔多克隆抗體
  • 貨號:
    CSB-PA942507
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA942507(ZMAT3 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA942507(ZMAT3 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    FLJ12296 antibody; FLJ31683 antibody; MGC10613 antibody; OTTHUMP00000211906 antibody; OTTHUMP00000211907 antibody; p53 activated gene 608 antibody; p53 inducible zinc finger protein antibody; p53 target zinc finger protein antibody; p53-activated gene 608 protein antibody; PAG 608 antibody; WIG 1 antibody; WIG 1/PAG608 protein antibody; WIG1 antibody; WIG1/PAG608 protein antibody; Wildtype p53-induced gene antibody; Zinc finger matrin type 3 antibody; Zinc finger matrin-type protein 3 antibody; Zinc finger protein WIG 1 antibody; Zinc finger protein WIG-1 antibody; Zinc finger protein WIG1 antibody; ZMAT 3 antibody; Zmat3 antibody; ZMAT3_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human ZMAT3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus.
  • 基因功能參考文獻:
    1. WIG1 governs the miRNA-dependent and the miRNA-independent recruitment of AGO2 to lower the stability of and suppress the translation of ACOT7 mRNA. PMID: 28472401
    2. we propose that Wig1, a key p53 downstream molecule in HD condition, play an important role in stabilizing mutant Htt mRNA and thereby accelerating HD pathology in the mHtt-p53-Wig1 positive feedback manner PMID: 27206983
    3. expression of the p53 target Wig-1 is associated with HPV status and patient survival in cervical carcinoma PMID: 25379706
    4. Results suggest a role of Wig-1 as a survival factor that directs the p53 stress response toward cell cycle arrest rather than apoptosis through the regulation of FAS and 14-3-3sigma mRNA levels. PMID: 24469038
    5. PSF and MATR3 are cellular host factors that bind viral RNA and promote Rev activity. PMID: 23158102
    6. The data indicated a novel role for Wig1 in RNA-induced silencing complex target accessibility, which is a key step in RNA-mediated gene silencing. Fine tuning of p21 levels by Wig1 was essential for the prevention of cellular senescence. PMID: 23085987
    7. Wig-1 knockdown causes a dramatic inhibition of N-Myc expression and triggers differentiation in neuroblastoma cells carrying amplified N-Myc. PMID: 22513872
    8. WIG-1 might be involved in the zinc-induced cell cycle arrest and apoptosis of human esophageal squamous cell carcinoma cells PMID: 21559779
    9. WIG-1 might be a novel modifier in esophageal carcinogenesis, and the WIG-1 MAb should be useful in further study of the mechanism in WIG-1-related physiological reactions. PMID: 21050045
    10. The cellular distribution of the nuclear matrix protein matrin 3 is altered by novel phosphorylation induced by the alphaherpesvirus US3 kinase family. PMID: 20962082
    11. Results demonstrate that human Wig-1 can bind different types of double-stranded RNAs (dsRNAs), including dsRNAs resembling small interfering RNAs and microRNAs, and indicate that dsRNA binding has a role in Wig-1-mediated regulation of cell growth. PMID: 16844115
    12. Wig-1-binding proteins, hnRNP A2/B1 and RNA Helicase A, both of which are involved in RNA processing, were identified. PMID: 18519039
    13. Data demonstrated a direct interaction between Dicer and Wig-1 and both may play a common role in dsRNA-related gene regulation. PMID: 19127773
    14. the p53 target Wig-1 is a previously undescribed AU-rich element-regulating protein that acts as a positive feedback regulator of p53, with implications both for the steady-state levels of p53 and for the p53 stress response PMID: 19805223

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Nucleus, nucleolus.
  • 組織特異性:
    Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine.
  • 數據庫鏈接:

    HGNC: 29983

    OMIM: 606452

    KEGG: hsa:64393

    STRING: 9606.ENSP00000311221

    UniGene: Hs.371609



主站蜘蛛池模板: 亚洲欧洲日产国码在线| 1000部夫妻午夜免费| 美女大量吞精在线观看456| 成人毛片一区二区| 硬了进去湿好大娇喘视频 | 亚洲精品你懂的在线观看| 久久久亚洲精品av无码| 欧美群妇大交群| 大肉大捧一进一出好爽mba| 亚洲有无码av在线播放| 国产成人精品视觉盛宴| 中文字幕日韩人妻无码 | 亚洲欧美日韩成人一区| 中无码人妻丰满熟妇啪啪| 亚洲精品一区二区中文字幕| 一本热久久sm色国产| 亚洲蜜桃v妇女| 久久精品中文字幕无码 | 国产福利免费视频不卡| 亚洲爆乳无码精品aaa片蜜桃 | 久久久一本精品久久精品六六| 国产在线拍揄自揄拍无码视频| 久久精品99久久香蕉国产色戒 | 成人国产网站v片免费观看| 亚洲精品入口一区二区乱麻豆精品 | 国产在线观看免费视频软件| 野花社区www视频最新资源| 日本中文字幕在线| 欧美性生交大片18禁止| 熟女熟妇伦av网站| 少妇人妻精品无码专区视频| 国产精品美女久久久久| 十八岁以下禁止观看黄下载链接| 国产亚洲人成在线播放| 三个男人躁我一个爽视频免费| 女人喷潮完整视频| 久久久精品中文字幕麻豆发布| 四虎永久免费地址入口| 青青草99久久精品国产综合| 亚洲人ⅴsaⅴ国产精品| 成年女人色毛片|