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  4. ZBTB32 Antibody, FITC conjugated

ZBTB32 Antibody, FITC conjugated

  • 中文名稱：
    ZBTB32兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA897538LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ZBTB32 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ZBTB32
  • 別名：
    FANCC interacting protein antibody; FANCC-interacting protein antibody; Fanconi anemia zinc finger protein antibody; FAXF antibody; FAZF antibody; OTTHUMP00000045790 antibody; repressor of GATA antibody; Rog antibody; Testis zinc finger protein antibody; ZBT32_HUMAN antibody; Zbtb32 antibody; ZBTB32 protein antibody; Zinc finger and BTB domain containing 32 antibody; Zinc finger and BTB domain-containing protein 32 antibody; Zinc finger protein 538 antibody; ZNF538 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Zinc finger and BTB domain-containing protein 32 protein (1-294AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells.
  • 基因功能參考文獻：
    1. ZBTB32 is a novel negative regulator of antibody recall responses. PMID: 27357154
    2. confirmed that the promyelocytic leukemia zinc finger (PLZF) BTB dimer is strand exchanged in solution, while the FAZF BTB dimer is not PMID: 20493880
    3. Here, it was shown that human endogenous retrovirus Rec can form a trimeric complex with TZFP and AR, and can relieve the TZFP-mediated repression of AR-induced transactivation. PMID: 20147518
    4. can interact with GATA-2 and can modify GATA-2 transactivation capacity PMID: 11964310
    5. results suggest an essential role for FAZF during the proliferative stages of primitive hematopoietic progenitors, possibly acting in concert with (a subset of) the Fanconi anemia proteins PMID: 11986317
    6. TZFP is identified as a novel BMP2-induced transcription factor during osteoblastic differentiation. PMID: 17171645

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  • 亞細胞定位：
    Nucleus. Note=Located in nuclear speckles.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 組織特異性：
    Predominantly expressed in testis. Some isoforms are ubiquitously expressed.
  • 數據庫鏈接：

    HGNC: 16763

    OMIM: 605859

    KEGG: hsa:27033

    STRING: 9606.ENSP00000262630

    UniGene: Hs.99430



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