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ZBTB32 Antibody, Biotin conjugated

  • 中文名稱:
    ZBTB32兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA897538LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) ZBTB32 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ZBTB32
  • 別名:
    FANCC interacting protein antibody; FANCC-interacting protein antibody; Fanconi anemia zinc finger protein antibody; FAXF antibody; FAZF antibody; OTTHUMP00000045790 antibody; repressor of GATA antibody; Rog antibody; Testis zinc finger protein antibody; ZBT32_HUMAN antibody; Zbtb32 antibody; ZBTB32 protein antibody; Zinc finger and BTB domain containing 32 antibody; Zinc finger and BTB domain-containing protein 32 antibody; Zinc finger protein 538 antibody; ZNF538 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Zinc finger and BTB domain-containing protein 32 protein (1-294AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells.
  • 基因功能參考文獻(xiàn):
    1. ZBTB32 is a novel negative regulator of antibody recall responses. PMID: 27357154
    2. confirmed that the promyelocytic leukemia zinc finger (PLZF) BTB dimer is strand exchanged in solution, while the FAZF BTB dimer is not PMID: 20493880
    3. Here, it was shown that human endogenous retrovirus Rec can form a trimeric complex with TZFP and AR, and can relieve the TZFP-mediated repression of AR-induced transactivation. PMID: 20147518
    4. can interact with GATA-2 and can modify GATA-2 transactivation capacity PMID: 11964310
    5. results suggest an essential role for FAZF during the proliferative stages of primitive hematopoietic progenitors, possibly acting in concert with (a subset of) the Fanconi anemia proteins PMID: 11986317
    6. TZFP is identified as a novel BMP2-induced transcription factor during osteoblastic differentiation. PMID: 17171645

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  • 亞細(xì)胞定位:
    Nucleus. Note=Located in nuclear speckles.
  • 蛋白家族:
    Krueppel C2H2-type zinc-finger protein family
  • 組織特異性:
    Predominantly expressed in testis. Some isoforms are ubiquitously expressed.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 16763

    OMIM: 605859

    KEGG: hsa:27033

    STRING: 9606.ENSP00000262630

    UniGene: Hs.99430



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