在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

VSIG4 Antibody

  • 中文名稱:
    VSIG4兔多克隆抗體
  • 貨號:
    CSB-PA896869LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA896869LA01HU at dilution of 1:100
    • Immunofluorescent analysis of A549 cells using CSB-PA896869LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) VSIG4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Complement receptor of the immunoglobulin superfamily antibody; CRIg antibody; Ig superfamily protein antibody; Protein Z39Ig antibody; UNQ317/PRO362 antibody; V set and immunoglobulin domain containing 4 antibody; V-set and immunoglobulin domain-containing protein 4 antibody; VSIG4 antibody; VSIG4_HUMAN antibody; Z39IG antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human V-set and immunoglobulin domain-containing protein 4 protein (20-283AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,VSIG4 Antibody (CSB-PA896869LA01HU),的標記方式是Non-conjugated。對于VSIG4 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA896869LB01HU VSIG4 Antibody, HRP conjugated ELISA
    FITC CSB-PA896869LC01HU VSIG4 Antibody, FITC conjugated
    Biotin CSB-PA896869LD01HU VSIG4 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.
  • 基因功能參考文獻:
    1. Soluble VSIG4 levels are associated with the progression and recurrence of ovarian cancer, indicating that soluble VSIG4 may be used as a potential biomarker for predicting tumor prognosis. PMID: 28498255
    2. VSIG4 signaling provides an anti-immune evasion mechanism that prevents the outgrowth of intracellular bacteria in macrophages PMID: 27440002
    3. The VSIG4 upregulation by LMP1 was regulated at the transcriptional level via the NF-kB signaling axis. PMID: 28859984
    4. VSIG4 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    5. we concluded that let-7g-5p inhibits epithelial-mesenchymal transition (EMT) consistent with reduction of glioma stem cell (GSC) phenotypes by targeting VSIG4 in glioblastoma. PMID: 27634309
    6. Data indicate that rotein kinase calpha (PKCalpha) plays a role in downregulating complement receptor Ig (CRIg coded by V-set and Ig domain-containing protein 4 VSIG4) expression. PMID: 25687755
    7. complement receptor of the immunoglobulin superfamily-L-factor H protects glomerular mesangial cells from complement-mediated injury and proliferative lesions PMID: 25114177
    8. we identified VSIG4 as a potential diagnostic marker of severe preeclampsia. The determination of this gene may improve the prognostic assessment of severe preeclampsia. PMID: 24349325
    9. Data indicate that massive V-set and Ig domain-containing 4 VSIG4(+) cell infiltration throughout the non-small-cell lung cancer samples. PMID: 24862966
    10. we showed that a complement receptor of the Ig superfamily (CRIg, also known as Z39Ig), a receptor for complement fragments (C3b and iC3b), was expressed on a subset of intestinal macrophages in murine and human large intestine PMID: 21768202
    11. These results suggest that T cells can opposite T cell hyporesponsiveness through dampening Z39Ig inhibitory signals from macrophages and thus maintain their anti-viral function in chronic hepatitis B. PMID: 20399148
    12. hVSIG4 recombinant adenovirus-transfected DCs suppress T cell proliferation, cytokine production and activation marker expression with PMID: 19914289
    13. Results report the identification and characterization of a Complement Receptor of the Immunoglobulin superfamily, CRIg, that binds complement fragments C3b and iC3b. PMID: 16530040
    14. These data indicate that the macrophage Z39Ig is involved in the pathogenesis of inflammatory diseases through chemokine induction, which will promote the migration of inflammatory cells into the lesion area, and MMP-9 induction. PMID: 16882875
    15. The specific expression of VSIG4 on resting macrophages suggests that VSIG4 may be important for the maintenance of T cell unresponsiveness in healthy tissues. PMID: 17016562
    16. CRIg is not only a phagocytic receptor, but also a potent inhibitor of the alternative pathway convertases PMID: 17051150

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Abundantly expressed in several fetal tissues. In adult tissues, highest expression in lung and placenta. Expressed in resting macrophages.
  • 數據庫鏈接:

    HGNC: 17032

    OMIM: 300353

    KEGG: hsa:11326

    STRING: 9606.ENSP00000363869

    UniGene: Hs.8904



主站蜘蛛池模板: 日本内射精品一区二区视频| 亚洲人成图片小说网站| 22222se男人的天堂| 国产精品久久久久久影视 | 国产日产欧产精品精品ai | 野狼av午夜福利在线| 亚洲无线观看国产精品| 99视频国产精品免费观看| 国产高清在线精品一区免费| 波多野结衣av无码久久一区| 日韩精品中文字幕无码专区| 亚洲已满18点击进入在线观看 | 男人和女人做爽爽视频| 精品久久久噜噜噜久久久| 亚洲精品欧美精品日韩精品| 国产自在自线午夜精品| 窝窝午夜看片| 欧美深性狂猛ⅹxxx深喉| 成人午夜电影福利免费| 亚洲综合激情七月婷婷| 99久久国产综合精品麻豆| 日韩精品久久久肉伦网站| 国产精品爽爽久久久久久无码| 被拉到野外强要好爽黑人| 国产精品18久久久久久麻辣| 亚洲欧美日韩成人综合一区| 无码专区手机在线播放| 久久天天躁狠狠躁夜夜2020一| 性色av极品无码专区亚洲| 国内精品国语自产拍在线观看 | 亚洲 欧美 另类 综合 日韩| 日韩不卡1卡2卡三卡2021免费| 狠狠色综合激情丁香五月| 日韩插啊免费视频在线观看| 亚洲天堂在线观看完整版| 国产一区日韩二区欧美三区| 国产真实乱对白精彩| 西西人体大胆扒开下部337卩| 蜜桃av噜噜一区二区三区| 欧美性生 活18~19| 动漫av永久无码精品每日更新|