在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. VPS34 Antibody

VPS34 Antibody

Rare Species
  • 中文名稱：
    VPS34 Antibody
  • 貨號：
    CSB-PA334903XA01SVG
  • 規格：
    ￥880
  • 圖片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:VPS34 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/20000 dilution
      Predicted band size: 28 kDa
      Observed band size: 30 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) VPS34 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    VPS34
  • 別名：
    Phosphatidylinositol 3-kinase VPS34 (PI3-kinase VPS34) (PI3K VPS34) (PtdIns-3-kinase VPS34) (EC 2.7.1.137) (Carboxypeptidase Y-deficient protein 15) (Vacuolar protein sorting-associated protein 34) (Vacuolar protein-targeting protein 29) VPS34 END12 PEP15 VPL7 VPT29 YLR240W L9672.10
  • 宿主：
    Rabbit
  • 反應種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 免疫原：
    Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) VPS34 protein (593-859aa)
  • 免疫原種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Phosphatidylinositol 3-kinase required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I. This complex is essential to recruit the ATG8-phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure. Also involved in endosome-to-Golgi retrograde transport as part of the VPS34 PI3-kinase complex II. This second complex is required for the endosome-to-Golgi retrieval of PEP1 and KEX2, and the recruitment of VPS5 and VPS7, two components of the retromer complex, to endosomal membranes (probably through the synthesis of a specific pool of phosphatidylinositol 3-phosphate recruiting the retromer to the endosomes). Its activation by VPS15 may lead to the phosphorylation of phosphatidylinositol in the sorting compartment membrane. Finally, it might also be involved in ethanol tolerance and cell wall integrity.
  • 基因功能參考文獻：
    1. Data indicate that class Ia Phosphatidylinositol 3-Kinase p85alpha germ line mutations associated with SHORT syndrome did not increase PI3K activity in the yeast model. PMID: 28143957
    2. mutants lacking Vps34 display multiple phenotypes indicating impaired transcription elongation. PMID: 23335340
    3. VPS34 plays a critical role in the decline of extracellular FBPase in response to glucose. PMID: 22833678
    4. Kes1-mediated regulation of the autophagy/cytoplasm to the vacuole trafficking pathway is prevented by increasing expression of the PI3K Vps34 PMID: 20729555
    5. Gpa1 is present at endosomes, where it interacts directly with both Vps34 and Vps15 and stimulates increased production of phosphatidylinositol 3-phosphate. PMID: 16839886
    6. Study shows that the lipid-kinase activity of Vps34 is required for autophagy, implying an essential role of its product PtdIns(3)P. PMID: 18533003

    顯示更多

    收起更多

  • 亞細胞定位：
    Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
  • 蛋白家族：
    PI3/PI4-kinase family
  • 數據庫鏈接：

    KEGG: sce:YLR240W

    STRING: 4932.YLR240W



主站蜘蛛池模板： 人与禽交videos欧美| 国产乱辈通伦影片在线播放亚洲| 人禽伦免费交视频播放| 国产看真人毛片爱做a片| 三级久久试看3分钟| av片日韩一区二区三区在线观看| 国产精品一区二区 尿失禁| 日产精品一区二区| 四虎国产精品永久在线国在线| 看国产一毛片在线看手机看| 久久97超碰色中文字幕总站| 亚洲最大天堂无码精品区| 在线看片无码永久av| 男女裸交无遮挡啪啪激情试看| 欧美日韩精品一区二区在线观看| 中文乱码字慕人妻熟女人妻| 精品国内自产拍在线播放观看| 伊人色综合网久久天天| 久久久精品人妻无码专区不卡| 久久综合色之久久综合| 99re久久资源最新地址| 日韩放荡少妇无码视频| 国产人久久人人人人爽| 亚洲日韩欧美一区二区三区在线| 草裙社区精品视频三区免费看| 真人与拘做受免费视频一| 韩国理伦片一区二区三区在线播放| 亚洲欧美成人a∨观看| 精品无码久久久久久尤物| 亚洲自偷自拍熟女另类| 国产精品成人久久电影| 日韩精品亚洲人旧成在线| 乌克兰少妇xxxx做受野外| 噜噜噜亚洲色成人网站| 欧美人与动人物姣配xxxx| 国产黄在线观看免费观看软件| 亚洲日韩中文字幕无码一区| 亚洲欧美日韩在线码| 青青草无码精品伊人久久| 成年美女黄网站色大免费视频 | 亚洲乱码国产乱码精品精大量|