在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

VPS16 Antibody

  • 中文名稱:
    VPS16兔多克隆抗體
  • 貨號:
    CSB-PA203811
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA203811(VPS16 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    VPS16
  • 別名:
    HGNC:14584 antibody; hVPS16 antibody; mVPS16 antibody; RP11 12M19.2 antibody; Vacuolar protein sorting 16 (yeast) antibody; Vacuolar protein sorting 16 (Yeast); isoform CRA_a antibody; Vacuolar protein sorting 16 antibody; Vacuolar protein sorting 16 homolog (S. cerevisiae) antibody; vacuolar protein sorting associated protein 16 homolog antibody; Vacuolar protein sorting protein 16 antibody; Vacuolar protein sorting-associated protein 16 homolog antibody; VPS16 antibody; VPS16_HUMAN antibody; VPS16A antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Fusion protein of Human VPS16
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Required for recruitment of VPS33A to the HOPS complex. Required for fusion of endosomes and autophagosomes with lysosomes; the function is dependent on its association with VPS33A but not VPS33B. The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG.
  • 基因功能參考文獻:
    1. VPS16 is a new causative gene for adolescent-onset primary dystonia. PMID: 27174565
    2. HOPS subunit Vps16 recruits Vps33A to the human HOPS complex; residues 642-736 are necessary and sufficient for this interaction. PMID: 23901104
  • 相關疾病:
    VSP16 mutation have been found in one familly with adolescent-onset primary dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures.
  • 亞細胞定位:
    Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Cytoplasmic vesicle, clathrin-coated vesicle. Cytoplasmic vesicle, autophagosome.
  • 蛋白家族:
    VPS16 family
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 14584

    OMIM: 608550

    KEGG: hsa:64601

    STRING: 9606.ENSP00000369810

    UniGene: Hs.269577



主站蜘蛛池模板: 超碰免费公开| 午夜无码精品国产片| 黑人大战欲求不满人妻| 女人被男人躁得好爽免费视频 | 亚洲乱码无码永久不卡在线| 国产欧美va天堂在线电影| 国产v在线最新观看视频| 国产亚洲婷婷香蕉久久精品| 亚洲国产av无码精品无广告| 在线观看日本亚洲一区| 成人h无码动漫超w网站| 一本色综合亚洲精品蜜桃冫| 亚洲精品成人无码中文毛片不卡| 亚洲欧美日韩在线码| 国产亚洲日本精品无码| 日本中文字幕乱码免费| 中文在线а天堂中文在线新版| 成年午夜精品久久久精品| 亚洲伊人情人综合网站| 一区二区国产高清视频在线| 日韩视频在线观看| 国产欧美在线一区二区三 | 久久久久女教师免费一区| 亚洲精品久久久一二三区 | 成 人 综合 亚洲另类| 无码午夜人妻一区二区不卡视频| 国产精品激情| 欧美亚洲一区二区三区| 2020精品国产视| 国产成人无码短视频| 国模冰莲极品自慰人体| 亚洲αv无码一区二区三区四区| 国产999久久高清免费观看| 国产欧美一区二区精品久久久 | 亚洲午夜成人片| 日本乱偷互换人妻中文字幕| 亚洲va在线va天堂va欧美va| 欧美日韩不卡合集视频| 欧美多人片高潮野外做片黑人 | 亚洲aⅴ在线无码播放毛片一线天 吃奶摸下高潮60分钟免费视频 | 亚州性无码不卡免费视频 |