在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. UVSSA Antibody

UVSSA Antibody

  • 中文名稱：
    UVSSA兔多克隆抗體
  • 貨號：
    CSB-PA012267LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA012267LA01HU diluted at 1:400 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) UVSSA Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    UVSSA
  • 別名：
    hypothetical protein LOC57654 antibody; K1530_HUMAN antibody; KIAA1530 antibody; Uncharacterized protein KIAA1530 antibody; UV stimulated scaffold protein A antibody; UVSS3 antibody; UVSSA antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human UV-stimulated scaffold protein A protein (143-206AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，UVSSA Antibody (CSB-PA012267LA01HU)，的標(biāo)記方式是Non-conjugated。對于UVSSA Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA012267LB01HU UVSSA Antibody, HRP conjugated ELISA
    FITC CSB-PA012267LC01HU UVSSA Antibody, FITC conjugated
    Biotin CSB-PA012267LD01HU UVSSA Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the nucleotide excision repair machinery. Not involved in processing oxidative damage.
  • 基因功能參考文獻(xiàn)：
    1. Data suggest that a common TFIIH subunit p62 recruitment mechanism is shared by UV-stimulated scaffold protein A (UVSSA) in transcription-coupled repair (TCR) and xeroderma pigmentosum, complementation group C protein (XPC) in global genome repair (GGR). PMID: 29069470
    2. stabilization of UVSSA by interaction with USP7 is essential for Transcription-coupled Nucleotide Excision Repair PMID: 27129218
    3. UVSSA together with USP7 is implicated in regulating transcription-coupled DNA repair.[review] PMID: 23760561
    4. Human UVSSA protein is required for the ubiquitination of RNA polymerase and DNA repair after light-induced DNA damage [review]. PMID: 23631307
    5. KIAA1530 is an important player in TCR but also lead to a better understanding of the molecular mechanism underlying UV(s)S syndrome. PMID: 22902626
    6. Mutations in the UVSSA gene is associated with UV-sensitive syndrome. PMID: 22466610
    7. Mutations in UVSSA cause UV-sensitive syndrome and recruits USP7 to regulate transcription-coupled repair. PMID: 22466611
    8. Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair. PMID: 22466612

    顯示更多

    收起更多

  • 相關(guān)疾病：
    UV-sensitive syndrome 3 (UVSS3)
  • 亞細(xì)胞定位：
    Chromosome.
  • 蛋白家族：
    UVSSA family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29304

    OMIM: 614632

    KEGG: hsa:57654

    STRING: 9606.ENSP00000374501

    UniGene: Hs.380475



主站蜘蛛池模板： 上司人妻互换中文字幕| av激情亚洲男人的天堂| 久久国产人妻一区二区免费| 九九re6热在线视频精品66| 精品黑人一区二区三区久久| 99在线精品视频在线观看| 亚洲精品入口一区二区乱麻豆精品 | 国产乱xxⅹxx国语对白| 玩弄少妇高潮ⅹxxxyw| 亚洲аv电影天堂网| 亚洲成a∧人片在线播放无码| 国产女人18毛片水真多18精品 | 亚洲日本中文字幕乱码在线| 亚洲成av人片在线观看无| 性猛交ⅹxxx富婆视频| 人人澡人摸人人添| 内射一区二区精品视频在线观看 | 99久久无码一区人妻a片蜜| 天天躁夜夜躁天干天干2020| a在线视频v视频| 成人做爰www网站视频| 婷婷五月俺也去人妻| 国产一区二区三区不卡在线看| 97精品国产手机| 色欲精品国产一区二区三区av| 午夜成人影院网站18进| 久久久国产精品黄毛片| h肉动漫无码无修6080动漫网| 亚洲国内精品自在线影院| 狠狠综合久久久久尤物| 欧美老妇与zozoz0交| 成年无码动漫av片在线观看羞羞| 国语高潮无遮挡无码免费看| 亚洲第一页综合图片自拍| 韩产日产国产欧产| 蜜臀精品国产高清在线观看| 亚洲一卡2卡3卡4卡精品| 国产精品久久人妻无码网站一区| 538prom精品视频在线播放| 成人做受120秒试看试看视频| 午夜福利理论片在线观看|