在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. UVSSA Antibody

UVSSA Antibody

  • 中文名稱：
    UVSSA兔多克隆抗體
  • 貨號：
    CSB-PA012267LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA012267LA01HU diluted at 1:400 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) UVSSA Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    UVSSA
  • 別名：
    hypothetical protein LOC57654 antibody; K1530_HUMAN antibody; KIAA1530 antibody; Uncharacterized protein KIAA1530 antibody; UV stimulated scaffold protein A antibody; UVSS3 antibody; UVSSA antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human UV-stimulated scaffold protein A protein (143-206AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，UVSSA Antibody (CSB-PA012267LA01HU)，的標(biāo)記方式是Non-conjugated。對于UVSSA Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA012267LB01HU UVSSA Antibody, HRP conjugated ELISA
    FITC CSB-PA012267LC01HU UVSSA Antibody, FITC conjugated
    Biotin CSB-PA012267LD01HU UVSSA Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the nucleotide excision repair machinery. Not involved in processing oxidative damage.
  • 基因功能參考文獻(xiàn)：
    1. Data suggest that a common TFIIH subunit p62 recruitment mechanism is shared by UV-stimulated scaffold protein A (UVSSA) in transcription-coupled repair (TCR) and xeroderma pigmentosum, complementation group C protein (XPC) in global genome repair (GGR). PMID: 29069470
    2. stabilization of UVSSA by interaction with USP7 is essential for Transcription-coupled Nucleotide Excision Repair PMID: 27129218
    3. UVSSA together with USP7 is implicated in regulating transcription-coupled DNA repair.[review] PMID: 23760561
    4. Human UVSSA protein is required for the ubiquitination of RNA polymerase and DNA repair after light-induced DNA damage [review]. PMID: 23631307
    5. KIAA1530 is an important player in TCR but also lead to a better understanding of the molecular mechanism underlying UV(s)S syndrome. PMID: 22902626
    6. Mutations in the UVSSA gene is associated with UV-sensitive syndrome. PMID: 22466610
    7. Mutations in UVSSA cause UV-sensitive syndrome and recruits USP7 to regulate transcription-coupled repair. PMID: 22466611
    8. Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair. PMID: 22466612

    顯示更多

    收起更多

  • 相關(guān)疾病：
    UV-sensitive syndrome 3 (UVSS3)
  • 亞細(xì)胞定位：
    Chromosome.
  • 蛋白家族：
    UVSSA family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29304

    OMIM: 614632

    KEGG: hsa:57654

    STRING: 9606.ENSP00000374501

    UniGene: Hs.380475



主站蜘蛛池模板： 中文字幕日韩精品有码视频 | av无码国产在线观看岛国| 免费乱码人妻系列无码专区| 国产成人av激情在线播放| 香港三级日本三级妇三级| 免费观看美女裸体网站| 国产大量精品视频网站| 成人国产精品无码网站| 美女av一区二区三区| 全免费又大粗又黄又爽少妇片| 久久国产福利国产秒拍飘飘网| 国产超碰人人爽人人做av| 一本久道久久综合狠狠躁av| 粉嫩少妇内射浓精videos| 蜜臀av在线观看| 97夜夜澡人人双人人人喊| 亚洲熟妇av午夜无码不卡| 国产人妻黑人一区二区三区| 2024av天堂手机在线观看| 日本一道高清一区二区三区| 国模无码一区二区三区不卡| 中国精品偷拍区偷拍无码| 夜夜未满十八勿进的爽爽影院| 日韩在线不卡免费视频一区| 蜜桃av蜜臀av色欲av麻| 日本亚洲欧洲另类图片| 亚洲a∨国产av综合av| 午夜寂寞少妇aaa片毛片| 国产精品美女久久久久久久久| 欧美熟妇性xxx交潮喷| 日本xxxx18野外无毒不卡| 久久99日韩国产精品久久99 | 中文字幕乱码亚洲无线码三区| 国产影片av级毛片特别刺激| 四房播播开心五月| 精品黑人一区二区三区久久| 亚洲国产欧美在线观看| 影音先锋每日av色资源站| 国产美女久久久亚洲综合| 亚洲欧美国产制服图片区| 国产成人无码av大片大片在线观看|