在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

UBR2 Antibody, FITC conjugated

  • 中文名稱:
    UBR2兔多克隆抗體, FITC偶聯(lián)
  • 貨號:
    CSB-PA809001LC01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) UBR2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    UBR2
  • 別名:
    UBR2 antibody; C6orf133 antibody; KIAA0349 antibody; E3 ubiquitin-protein ligase UBR2 antibody; EC 2.3.2.27 antibody; N-recognin-2 antibody; RING-type E3 ubiquitin transferase UBR2 antibody; Ubiquitin-protein ligase E3-alpha-2 antibody; Ubiquitin-protein ligase E3-alpha-II antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human E3 ubiquitin-protein ligase UBR2 protein (101-439AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth. Required for spermatogenesis, promotes, with Tex19.1, SPO11-dependent recombination foci to accumulate and drive robust homologous chromosome synapsis. Polyubiquitinates LINE-1 retrotransposon encoded, LIRE1, which induces degradation, inhibiting LINE-1 retrotransposon mobilization. Catalyzes ubiquitination and degradation of the N-terminal part of NLRP1 following NLRP1 activation by pathogens and other damage-associated signals: ubiquitination promotes degradation of the N-terminal part and subsequent release of the cleaved C-terminal part of NLRP1, which polymerizes and forms the NLRP1 inflammasome followed by host cell pyroptosis.
  • 基因功能參考文獻:
    1. There was a significant difference between the oligospermia men (oligospermia group) and the fertile men (control group) observed in this research that could indicate that the combined AT-TC-CC genotype in the UBR2 gene (rs16895863, rs373341, rs3749897 respectively) is a possible risk of idiopathic oligospermia for men in Sichuan, China. PMID: 26940145
    2. The c.1,066A>T variant in the UBR2 gene is associated with increased susceptibility to azoospermia caused by meiotic arrest. PMID: 21573678
    3. Study provides functional data for the mouse ubiquitin protein ligase E3 component n-recognin 2 protein. PMID: 14585983
  • 亞細胞定位:
    Nucleus. Chromosome.
  • 蛋白家族:
    UBR1 family
  • 組織特異性:
    Broadly expressed, with highest levels in skeletal muscle, kidney and pancreas. Present in acinar cells of the pancreas (at protein level).
  • 數(shù)據(jù)庫鏈接:

    HGNC: 21289

    OMIM: 609134

    KEGG: hsa:23304

    STRING: 9606.ENSP00000361990

    UniGene: Hs.529925



主站蜘蛛池模板: 人妻熟女一区二区aⅴ图片| 少妇下面好紧好多水真爽播放| 国产va在线观看免费| 欧美成人va免费大片视频| 伊伊人成亚洲综合人网| 国产精品白浆无码流出视频| 国产一区二区三区不卡在线观看| 狠狠的干性视频| 亚洲精品美女久久久久99| 大屁股熟女白浆一区二区| 国产成人a区在线观看视频| 国产精品十八禁在线观看| 中文韩国午夜理伦三级好看| 亚洲女人色综合小说| 综合图区亚洲欧美另类图片| 日本一本二本三区免费| 无码国产偷倩在线播放| 少妇爱做高清免费视频| 国产日韩av免费无码一区二区三区 | 久久午夜夜伦鲁鲁片无码免费| 欧美成人看片一区二三区图文| 成人爽a毛片在线视频| 成人免费视频一区二区三区| 国产精品多p对白交换绿帽| 亚洲经典国产精华液单品榜| 又大又粗又长的高潮视频| 亚洲性啪啪无码av天堂| 无码色偷偷亚洲国内自拍| 色婷婷五月综合欧美图片| 人人妻人人澡人人爽精品欧美| 色悠久久久久久久综合网伊人| 国产在线视频天天综合网| 很黄很黄的曰批视频| 大肉大捧一进一出好爽视频| 特级a做爰全过程片| 国产成+人欧美+综合在线观看| 国产95在线 | 亚洲| 国产肥熟女视频一区二区三区| 天堂在/线中文在线资源8| 2020无码天天喷水天天爽| 久久伊人五月丁香狠狠色|