在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

UBL4A Antibody

  • 中文名稱:
    UBL4A兔多克隆抗體
  • 貨號:
    CSB-PA785877
  • 規(guī)格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA785877(UBL4A Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA785877(UBL4A Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    UBL4A
  • 別名:
    DX254E antibody; DXS254E antibody; G6PD antibody; GDX antibody; OTTHUMP00000061462 antibody; Ubiquitin like 4 antibody; Ubiquitin like 4A antibody; Ubiquitin like protein 4A antibody; Ubiquitin like protein GDX antibody; Ubiquitin-like protein 4A antibody; Ubiquitin-like protein GDX antibody; UBL 4 antibody; UBL 4A antibody; UBL4 antibody; Ubl4a antibody; UBL4A_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Full length fusion protein
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum. Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome. Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum. The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.
  • 基因功能參考文獻(xiàn):
    1. The authors identify USP13 as a gp78-associated deubiquitinase that eliminates ubiquitin conjugates from Ubl4A to maintain the functionality of Bag6. PMID: 24424410
    2. Structures of the Sgt2/SGTA dimerization domain with the Get5/UBL4A UBL domain reveal an interaction that forms a conserved dynamic interface. PMID: 23142665
  • 亞細(xì)胞定位:
    Cytoplasm, cytosol. Nucleus.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 12505

    OMIM: 312070

    KEGG: hsa:8266

    STRING: 9606.ENSP00000358674

    UniGene: Hs.76480



主站蜘蛛池模板: 狠狠噜天天噜日日噜| 国产精品久久久久电影网| 国产吃奶在线观看| 亚洲色欲综合一区二区三区| 欧美人与动牲交xxxxbbbb| 日韩一卡二卡三卡四卡免费观在线 | 国产成人一区二区三区在线| 欧美巨波霸乳影院| 欧美婷婷丁香五月社区| 久久综合给合久久97色| 无码国产一区二区免费| 国产女人高潮叫床视频| 日韩人妻无码制服丝袜视频| 亚洲性人人天天夜夜摸18禁止| 亚洲精品无码专区在线播放| 中文字幕无码乱码人妻系列蜜桃| 国模少妇一区二区三区| 137裸交肉体摄影| 中文无码av在线亚洲电影| .精品久久久麻豆国产精品| 强辱丰满人妻hd中文字幕| 亚洲欧美综合成人五月天网站| 国产女人乱子对白av片| 鲁丝一区二区三区免费| 国产日韩欧美亚洲精品中字| 曰韩a∨无码一区二区三区| 欧美日韩亚洲精品瑜伽裤| 亚洲欧美精品伊人久久| 538prom精品视频在线播放| www一区二区乱码www| 天天鲁一鲁摸一摸爽一爽| 国产精品卡一卡二卡三| 国产在线无码播放不卡视频| 国产国产精品人在线视| 亚洲成a人片在线观看中文| 国产福利男女xx00视频| 四虎影库久免费视频| 午夜男女爽爽影院免费视频下载| 婷婷久久综合九色综合绿巨人 | 特黄 做受又硬又粗又大视频| 日本老熟妇乱子伦视频|