在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

UBL4A Antibody, FITC conjugated

  • 中文名稱:
    UBL4A兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA025499LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) UBL4A Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    UBL4A
  • 別名:
    DX254E antibody; DXS254E antibody; G6PD antibody; GDX antibody; OTTHUMP00000061462 antibody; Ubiquitin like 4 antibody; Ubiquitin like 4A antibody; Ubiquitin like protein 4A antibody; Ubiquitin like protein GDX antibody; Ubiquitin-like protein 4A antibody; Ubiquitin-like protein GDX antibody; UBL 4 antibody; UBL 4A antibody; UBL4 antibody; Ubl4a antibody; UBL4A_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Ubiquitin-like protein 4A protein (1-157AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum. Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome. Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum. The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.
  • 基因功能參考文獻:
    1. The authors identify USP13 as a gp78-associated deubiquitinase that eliminates ubiquitin conjugates from Ubl4A to maintain the functionality of Bag6. PMID: 24424410
    2. Structures of the Sgt2/SGTA dimerization domain with the Get5/UBL4A UBL domain reveal an interaction that forms a conserved dynamic interface. PMID: 23142665
  • 亞細胞定位:
    Cytoplasm, cytosol. Nucleus.
  • 數據庫鏈接:

    HGNC: 12505

    OMIM: 312070

    KEGG: hsa:8266

    STRING: 9606.ENSP00000358674

    UniGene: Hs.76480



主站蜘蛛池模板: 亚洲综合无码一区二区| 人妻少妇88久久中文字幕| 久久激情五月丁香伊人| 色婷婷综合久色aⅴ五区最新| 国产福利一区二区三区在线观看 | 欧美一区内射最近更新| а√天堂资源中文在线官网| 欧美成人免费va影院高清| 粗大猛烈进出高潮视频| 国产人久久人人人人爽| 亚洲国产成人精品久久久| 久久天天躁夜夜躁狠狠躁2014 | 国产精品久久久久久久久动漫| 国产精品无码av天天爽 | 在线观看黄a∨免费无毒网站| 国产片a国产片免费看视频| 国产av无码专区亚汌a√| 精品无码无人网站免费视频| 国产成av人片在线观看天堂无码| 亚洲精品久久久无码大桥未久| 国产电影一区二区三区| 精品国产人妻一区二区三区 | 人人超人人超碰超国产97超碰| 亚洲久悠悠色悠在线播放 | 婷婷四房色播| 无码一区二区三区老色鬼| 真实国产乱子伦对白在线播放| 久久人妻天天av| 狠狠色噜噜狠狠狠狠av不卡| 精品久久久无码中文字幕一丶| 亚洲一区二区三区含羞草| 午夜阳光精品一区二区三区| 国产色诱视频在线观看| 国产美女裸身网站免费观看视频| 正在播放国产乱子伦最新视频| 日本真人做爰免费视频120秒| 国产农村妇女aaaaa视频| 亚洲一卡2卡三卡4卡国色天香| 国产欧美日韩va另类在线播放| 亚洲国产成人久久精品大牛影视| 久久精品国产精品国产一区|