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  4. TULP3 Antibody, Biotin conjugated

TULP3 Antibody, Biotin conjugated

  • 中文名稱：
    TULP3兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA025348LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TULP3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    MGC45295 antibody; Tubby like protein 3 antibody; Tubby related protein 3 antibody; Tubby-like protein 3 antibody; Tubby-related protein 3 antibody; TUBL 3 antibody; TUBL3 antibody; TULP 3 antibody; TULP3 antibody; TULP3_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Tubby-related protein 3 protein (1-260AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis. During adipogenesis, regulates ciliary trafficking of FFAR4 in preadipocytes.
  • 基因功能參考文獻：
    1. Data demonstrated that pancreatic cancer patients exhibiting high transcriptional levels of TULP3 showed a poor overall survival rate. PMID: 24668219
  • 亞細胞定位：
    Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm. Secreted.
  • 蛋白家族：
    TUB family
  • 組織特異性：
    Expressed at high levels in testis, ovaries, thyroid, and spinal chord.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 12425

    OMIM: 604730

    KEGG: hsa:7289

    STRING: 9606.ENSP00000380321

    UniGene: Hs.655333



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