在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TUBG1 Antibody, HRP conjugated

  • 中文名稱:
    TUBG1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA025334LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TUBG1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TUBG1
  • 別名:
    Gamma-1-tubulin antibody; Gamma-tubulin complex component 1 antibody; GCP-1 antibody; TBG1_HUMAN antibody; TUBG antibody; TUBG1 antibody; TUBGCP1 antibody; Tubulin gamma-1 chain antibody; Tubulin, gamma 1 antibody; Tubulin, gamma polypeptide antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Tubulin gamma-1 chain protein (29-184AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
  • 基因功能參考文獻:
    1. CCT actively promotes the formation of conformationally different aggregates of gamma-tubulin, a non-amyloidogenic CCT client protein, which are mediated by specific CCT-gamma-tubulin interactions. PMID: 29339327
    2. that in the face of predominant gamma-tubulin-1 expression, the accumulation of gamma-tubulin-2 in mature neurons and neuroblastoma cells during oxidative stress may denote a prosurvival role of gamma-tubulin-2 in neurons PMID: 28119396
    3. All GCPs are incorporated into the helix via lateral interactions between their N-terminal domains, whereas the C-terminal domains mediate longitudinal interactions with gamma-tubulin. PMID: 27660388
    4. While binding to gamma-tubulin may help target APC to the site of microtubule nucleation complexes, additional C-terminal sequences of APC are required to stimulate and stabilize microtubule growth. PMID: 26556314
    5. Results show that CUL4A- and CUL4B-mediated polyubiquitination of gamma-tubulin for its degradation. PMID: 25542213
    6. In this study, the molecular basis of interaction between two lateral gamma-tubulin units within the gamma-tubulin ring complex were elucidated by making extensive use of molecular mechanics and molecular dynamics techniques. PMID: 25031076
    7. Gamma tubulin expression was associated with patients' age, astrocytoma grade, respectability, patient survival and performance. These factors may be important prognostic indicators for patients with astrocytomas. PMID: 24620973
    8. Recombinant gamma-tubulin can be phosphorylated by Cdk1-cyclin B or Brsk1 and dephosphorylated by Ppp4c-R2-R3A in vitro. PMID: 23966160
    9. Nek9 phosphorylates NEDD1 on Ser377 driving its recruitment and thereby that of gamma-tubulin to the centrosome in mitotic cells. PMID: 22818914
    10. Our results reveal for the first time an increased expression of TUBG1 and TUBG2 in lung cancer PMID: 22806905
    11. overexpression of Cdk1 or BRCA1 greatly expands the gamma-tubulin coating of microtubules, suggesting that the microtubule-bound gamma-tubulin is involved in DNA damage response. PMID: 21951856
    12. in transformed as well as in non-transformed interphase mammalian cells gamma-tubulin is present not only in cytoplasm but also in nuclei and nucleoli where it can be translocated during mitosis PMID: 21465471
    13. These results thus report for the first time the identification of Cep70 as an important centrosomal protein that interacts with gamma-tubulin and underscore its critical role in the regulation of mitotic spindle assembly. PMID: 21795687
    14. The data presented here indicate that gamma-tubulin has a profound relationship with actin filament dynamics PMID: 21473851
    15. a direct interaction with NEDD1 regulates gamma-tubulin recruitment to the centrosome PMID: 20224777
    16. the 2.7-A crystal structure of human gamma-tubulin bound to GTP-gammaS (a non-hydrolysable GTP analogue) PMID: 15917813
    17. analysis of human ninein isoforms that are regulated by centrosomal targeting signals and bind to gamma-tubulin PMID: 17102634
    18. Data suggest that aberrant expression and interactions of betaIII-tubulin and gamma-tubulin may be linked to malignant changes in glial cells. PMID: 17406983
    19. GSK-3beta regulates the localization of gamma-tubulin ring complex, including GCP5, to the spindle poles, thereby controlling the formation of proper mitotic spindles PMID: 18316369
    20. The axial elastic modulus of tubulin diminishes as the length of the monomer increases. PMID: 18621829
    21. Increased expression of centrosomal TUBG in atypical ductal hyperplasia and carcinoma of the breast is reported. PMID: 19215229
    22. Stability of the small gamma-tubulin complex (gamma tubulin/GCP2/GCP3) requires HCA66, a protein of the centrosome and the nucleolus. PMID: 19299467
    23. Data suggest that sequential phosphorylation of Nedd1 by Cdk1 and Plk1 plays a role in targeting gamma tubulin ring complex to the centrosome by promoting the interaction of Nedd1 with the gammaTuRC component gamma-tubulin, during mitosis. PMID: 19509060
    24. Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components PMID: 19543530
    25. SADB kinase activity controls centrosome homeostasis by regulating phosphorylation of gamma-tubulin. PMID: 19648910

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Cortical dysplasia, complex, with other brain malformations 4 (CDCBM4)
  • 亞細胞定位:
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle.
  • 蛋白家族:
    Tubulin family
  • 數據庫鏈接:

    HGNC: 12417

    OMIM: 191135

    KEGG: hsa:7283

    STRING: 9606.ENSP00000251413

    UniGene: Hs.279669



主站蜘蛛池模板: 女人被狂躁的高潮免费视频| 动漫成人无码精品一区二区三区| 久久精品av一区二区免费| 国产久久精品| 麻豆人妻少妇精品无码专区| 黑人上司粗大拔不出来电影| 亚洲精品午夜一区人人爽| 性高朝久久久久久久| 欧美人与动性xxxxx杂| 亚洲精品国产福利一区二区| 亚洲国产成人久久一区久久| 国产精品视频二区不卡| 成人毛片无码一区二区三区 | 亚洲中文字幕日产无码成人片| 中文字幕 欧美精品 第1页| 少妇又色又紧又爽又刺激视频| 成人性生交大片免费看r链接| 亚洲国产精品久久久天堂麻豆宅男| 无码人妻丝袜视频在线播免费| 女女女女女裸体处开bbb| 波多野结衣av无码| 两性色午夜视频免费播放| 久久天天躁狠狠躁夜夜96流白浆 | 性开放的欧美大片| 欧美日韩精品一区二区三区不卡| 在线亚洲欧美日韩精品专区| 激情无码人妻又粗又大中国人| 国产99在线 | 中国| 人妻无码一区二区三区四区| 小辣椒福利视频导航| 亚洲中文无码av永久伊人| 久久国产精品久久久久久| 大伊香蕉精品视频在线天堂| 人人爽人人爽人人片av免费| 最近更新中文字幕免费大全| 草草影院发布页| 免费观看潮喷到高潮中文字幕| 亚洲色播永久网址大全| 男受被做哭激烈娇喘gv视频| 国产jjzzjjzz视频全部免费| 精品国产肉丝袜久久|