在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TTLL5 Antibody

TTLL5 Antibody

  • 中文名稱：
    TTLL5兔多克隆抗體
  • 貨號：
    CSB-PA715737LA01HU
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TTLL5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    KIAA0998 antibody; SRC1 and TIF2-associated modulatory protein antibody; STAMP antibody; TTLL5 antibody; TTLL5_HUMAN antibody; Tubulin polyglutamylase TTLL5 antibody; Tubulin--tyrosine ligase-like protein 5 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Tubulin polyglutamylase TTLL5 protein (1-269AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，TTLL5 Antibody (CSB-PA715737LA01HU)，的標(biāo)記方式是Non-conjugated。對于TTLL5 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA715737LB01HU TTLL5 Antibody, HRP conjugated ELISA
    FITC CSB-PA715737LC01HU TTLL5 Antibody, FITC conjugated
    Biotin CSB-PA715737LD01HU TTLL5 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Polyglutamylase which modifies tubulin, generating polyglutamate side chains on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin. Preferentially mediates ATP-dependent initiation step of the polyglutamylation reaction over the elongation step. Preferentially modifies the alpha-tubulin tail over a beta-tail. Required for CCSAP localization to both polyglutamylated spindle and cilia microtubules. Increases the effects of transcriptional coactivator NCOA2/TIF2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction.
  • 基因功能參考文獻(xiàn)：
    1. in a study of 3 family members from 2 generations, identified in a previously misdiagnosed incomplete congenital stationary night blindness (icCSNB) case a splice-site mutation in intron 3 of TTLL5 (c.182-3_182-1delinsAA); reinvestigation of the clinical data corrected the diagnosis to cone dystrophy PMID: 28356705
    2. 5 homozygous variants [p.(Asp594fs), p.(Gln117*), p.(Met712fs), p.(Ile756Phe) and p.(Glu543Lys)] in TTLL5, in 8 patients from 6 families were identified. 2 male patients carrying truncating TTLL5 variants also displayed a reduction in sperm motility and infertility, whereas those carrying missense changes were fertile. TTLL has multiple viable isoforms, being highly expressed in retina, testis and spermatozoon flagellum. PMID: 28173158
    3. this study has performed exome sequencing in 28 individuals with a similar disease phenotype and subsequently used a casecontrol approach to identify mutations in TTLL5 as a cause of recessive retinal dystrophy. PMID: 24791901
    4. This study indicates that a physiological function of STAMP in several settings is to modify cell growth rates in a manner that can be independent of steroid hormones. PMID: 20374646
    5. STAMP is an important new, downstream component of GR action in both gene activation and gene repression. PMID: 17116691

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Cone-rod dystrophy 19 (CORD19)
  • 亞細(xì)胞定位：
    Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Nucleus. Cytoplasm.
  • 蛋白家族：
    Tubulin--tyrosine ligase family
  • 組織特異性：
    Expressed in the retina, found in the rod and cone photoreceptors (at protein level). Widely expressed with highest levels in heart and skeletal muscle and low levels in other tissues.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19963

    OMIM: 612268

    KEGG: hsa:23093

    STRING: 9606.ENSP00000298832

    UniGene: Hs.709609



主站蜘蛛池模板： 在线不卡日本v一区二区| 亚洲国产精品成人精品无码区蜜臀| 狼友网精品视频在线观看| 亚洲va中文字幕无码久久不卡| 萝卜视频高清免费视频日本| 久久精品亚洲精品无码| 色悠久久久久久久综合网| 国产对白老熟女正在播放| 自慰系列无码专区| 性国产牲交xxxxx视频| 人妻熟妇乱又伦精品视频无广告| 美女视频黄频大全免费| 国产精品久久久久久一区二区三区| 国产精品亚洲w码日韩中文 | 精品影片在线观看的网站| 亚无码乱人伦一区二区| 久久久久国色av免费看图片| 久久久国产99久久国产久一| 欧美亚洲精品一区二区| 精品少妇人妻av无码久久| 国产精品久久久久av| 蜜色欲多人av久久无码| 秋霞午夜一区二区三区黄瓜视频 | 后入内射欧美99二区视频| 国产69精品久久久久乱码| 自拍偷自拍亚洲精品牛影院| 久久人人爽人人人人片| 国产精品毛片av在线看| 麻豆成人久久精品二区三区免费 | 亚洲精品无码久久久久| 亚洲精品1卡2卡三卡4卡乱码 | 少妇午夜福利一区二区| 人妻熟女一区二区aⅴ水野朝阳 | 欧美大荫蒂毛茸茸视频| 亚洲 日韩 欧美 成人 在线观看| 亚洲国产成在人网站天堂| 亚洲国产成人在人网站天堂| 无码成人精品区在线观看| 天堂av男人在线播放| 97国语精品自产拍在线观看| 国产小受呻吟gv视频在线观看|