在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TRIP6 Antibody

  • 中文名稱:
    TRIP6兔多克隆抗體
  • 貨號:
    CSB-PA024528GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    MGC10556 antibody; MGC10558 antibody; MGC29959 antibody; MGC3837 antibody; MGC4423 antibody; OIP-1 antibody; OIP1 antibody; OPA interacting protein 1 antibody; OPA-interacting protein 1 antibody; Thyroid hormone receptor interactor 6 antibody; Thyroid receptor interacting protein 6 antibody; Thyroid receptor-interacting protein 6 antibody; TR-interacting protein 6 antibody; TRIP-6 antibody; Trip6 antibody; TRIP6_HUMAN antibody; TRIP6i2 antibody; ZRP 1 antibody; ZRP-1 antibody; Zyxin-related protein 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human TRIP6
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor.
  • 基因功能參考文獻:
    1. Taken together, these findings showed that TRIP6 plays an important role in promoting HCC cells proliferation and may serve as a novel prognostic biomarker and therapeutic target in HCC. PMID: 29080747
    2. TRIP6 promotes tumor proliferation and reverses cell adhesion-mediated drug resistance via regulating nuclear p27(Kip1) expression in non-Hodgkin's lymphoma PMID: 26298725
    3. the Trip6-GRIP1-myosin VI interaction and its regulation on F-actin network play a significant role in dendritic morphogenesis PMID: 25673849
    4. TRIP6 acts, in contrast to Zyxin, as an oncogene that partially accounts for the autonomous migratory, invasive and proliferative properties of Ewing's sarcoma cells. PMID: 24033704
    5. TRIP6 overexpression promotes migration, invasion, and clonogenicity of Ewing's sarcoma cells PMID: 24033704
    6. TRIP6 is involved in the regulation of nasopharyngeal carcinoma cell motility, and phosphorylation of tyrosine 55 residue plays an important regulatory role for this event PMID: 23576104
    7. TRIP6 also promotes serum-induced reduction of nuclear p27(KIP1) expression levels. PMID: 23339869
    8. High TRIP6 expression is associated with malignant pleural mesothelioma. PMID: 23313295
    9. TRIP6 is engaged in cell proliferation, differentiation, transcription regulation and contributes to genome stability. [Review] PMID: 22054418
    10. TRIP6 is a nucleocytoplasmatic shuttle protein essential for the coordination of focal adhesion dynamics and transcriptional responses in lysophosphosphatidic (LPA) and NF-kappaB signaling. PMID: 22054418
    11. TRIP6 is an adaptor protein that regulates cell motility, antiapoptotic signaling and transcriptional activity. (Review) PMID: 21689746
    12. TRIP6 promotes Fas-mediated cell migration in apoptosis-resistant glioma cells. This effect is regulated via the Src-dependent phosphorylation of TRIP6 at Tyr-55. PMID: 20876301
    13. the OIP-1 c-peptide is the functional domain of OIP-1 PMID: 11771657
    14. TRIP6 functions at a point of convergence between the activated LPA(2) receptor and downstream signals involved in cell adhesion and migration PMID: 14688263
    15. ZRP-1 has a role in endoglin regulation of cytoskeletal organization PMID: 15148318
    16. The data establish a physical and functional association between TRIP6 and RIP2, and suggest that RIP2's involvement in multiple NF-kappaB and ERK activation pathways is mediated through TRIP6. PMID: 15657077
    17. Binding of LPP and TRIP6 to Scrib links Scrib to a communication pathway between cell-cell contacts and the nucleus, and implicates these zyxin family members in Scrib-associated functions. PMID: 16137684
    18. The TRIP6 knock-down led to an increased number of longer stress fibers and to the induction of locomotive phenotype in carcinoma cells. PMID: 16240724
    19. AMPK phosphorylated TRIP6 in vitro at the N-terminus and the transcriptional co-activator properties of TRIP6 were enhanced by AMPK action. PMID: 16624523
    20. ZRP-1 plays a crucial role in coupling the cell-matrix/cell-cell-contact signals with Rho GTPase-mediated actin remodeling by localizing at cell-matrix and cell-cell contact sites. PMID: 17652164
    21. OIP-1 inhibits measles virus nucleocapsid protein induced pagetic osteoclast formation/activity through suppression of RANK signaling PMID: 18348201
    22. TRIP6 overexpression in colon tumors suggests its critical role in cancer progression. PMID: 19017743
    23. IL-12 stimulates the OIP-1 gene expression through STAT-3 activation in CD4+ T cells. PMID: 19259951
    24. Analysis of the subcellular distribution of ZRP-1 demonstrated that in the absence of endoglin, ZRP-1 mainly localizes to focal adhesion sites, whereas in the presence of endoglin ZRP-1 is found along actin stress fibers. PMID: 15148318

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus. Cytoplasm.
  • 蛋白家族:
    Zyxin/ajuba family
  • 組織特異性:
    Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors.
  • 數據庫鏈接:

    HGNC: 12311

    OMIM: 602933

    KEGG: hsa:7205

    STRING: 9606.ENSP00000200457

    UniGene: Hs.534360



主站蜘蛛池模板: 国产成人精品视频ⅴa片软件竹菊 免费精品99久久国产综合精品 | 和黑人邻居中文字幕在线| 狠狠噜天天噜日日噜| 人人妻人人澡人人爽不卡视频| 老熟女 露脸 嗷嗷叫| 人妻丝袜av中文系列先锋影音 | 天堂中文资源库官网| 亚洲精品国产精品乱码不卡√| 国产欧美久久一区二区| 亚洲综合一区无码精品| 亚洲偷自拍国综合色帝国| 成人无码av网站在线观看| 四虎成人精品一区二区免费网站 | 亚洲综合精品伊人久久| 五月丁香啪啪激情综合色九色 | 久久久久蜜桃精品成人片公司| 精品人妻系列无码人妻漫画| 伊人色综合久久天天| 欧美506070老妇乱子伦| 99在线精品视频高潮喷吹| 热99re久久精品这里都是精品免费 | 射精区-区区三区| 欧美熟妇另类久久久久久不卡| 亚洲乱码卡一卡二卡新区豆| 亚洲精品午夜理伦不卡在线观看| 无码视频一区二区三区| 久久精品黄aa片一区二区三区 | 老妇肥熟凸凹丰满刺激| 国产成人精品一区二区三区免费看| 日本少妇xxxx做受| 欧美成人一区二区三区片免费 | 人妻aⅴ中文字幕无码| 亚洲高清最新av网站| 国产成人综合久久久久久| 日韩人妻无码一区二区三区综合| 国内少妇偷人精品视频| 亚洲老妈激情一区二区三区 | 色偷偷人人澡久久超碰97| 人妻av无码中文专区久久| 69精品人人人人| 欧美 亚洲 国产 日韩 综aⅴ|