在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TRIP6 Antibody

  • 中文名稱:
    TRIP6兔多克隆抗體
  • 貨號:
    CSB-PA112642
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA112642(TRIP6 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    MGC10556 antibody; MGC10558 antibody; MGC29959 antibody; MGC3837 antibody; MGC4423 antibody; OIP-1 antibody; OIP1 antibody; OPA interacting protein 1 antibody; OPA-interacting protein 1 antibody; Thyroid hormone receptor interactor 6 antibody; Thyroid receptor interacting protein 6 antibody; Thyroid receptor-interacting protein 6 antibody; TR-interacting protein 6 antibody; TRIP-6 antibody; Trip6 antibody; TRIP6_HUMAN antibody; TRIP6i2 antibody; ZRP 1 antibody; ZRP-1 antibody; Zyxin-related protein 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Fusion protein of Human TRIP6
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    IHC 1:30-1:150
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor.
  • 基因功能參考文獻:
    1. Taken together, these findings showed that TRIP6 plays an important role in promoting HCC cells proliferation and may serve as a novel prognostic biomarker and therapeutic target in HCC. PMID: 29080747
    2. TRIP6 promotes tumor proliferation and reverses cell adhesion-mediated drug resistance via regulating nuclear p27(Kip1) expression in non-Hodgkin's lymphoma PMID: 26298725
    3. the Trip6-GRIP1-myosin VI interaction and its regulation on F-actin network play a significant role in dendritic morphogenesis PMID: 25673849
    4. TRIP6 acts, in contrast to Zyxin, as an oncogene that partially accounts for the autonomous migratory, invasive and proliferative properties of Ewing's sarcoma cells. PMID: 24033704
    5. TRIP6 overexpression promotes migration, invasion, and clonogenicity of Ewing's sarcoma cells PMID: 24033704
    6. TRIP6 is involved in the regulation of nasopharyngeal carcinoma cell motility, and phosphorylation of tyrosine 55 residue plays an important regulatory role for this event PMID: 23576104
    7. TRIP6 also promotes serum-induced reduction of nuclear p27(KIP1) expression levels. PMID: 23339869
    8. High TRIP6 expression is associated with malignant pleural mesothelioma. PMID: 23313295
    9. TRIP6 is engaged in cell proliferation, differentiation, transcription regulation and contributes to genome stability. [Review] PMID: 22054418
    10. TRIP6 is a nucleocytoplasmatic shuttle protein essential for the coordination of focal adhesion dynamics and transcriptional responses in lysophosphosphatidic (LPA) and NF-kappaB signaling. PMID: 22054418
    11. TRIP6 is an adaptor protein that regulates cell motility, antiapoptotic signaling and transcriptional activity. (Review) PMID: 21689746
    12. TRIP6 promotes Fas-mediated cell migration in apoptosis-resistant glioma cells. This effect is regulated via the Src-dependent phosphorylation of TRIP6 at Tyr-55. PMID: 20876301
    13. the OIP-1 c-peptide is the functional domain of OIP-1 PMID: 11771657
    14. TRIP6 functions at a point of convergence between the activated LPA(2) receptor and downstream signals involved in cell adhesion and migration PMID: 14688263
    15. ZRP-1 has a role in endoglin regulation of cytoskeletal organization PMID: 15148318
    16. The data establish a physical and functional association between TRIP6 and RIP2, and suggest that RIP2's involvement in multiple NF-kappaB and ERK activation pathways is mediated through TRIP6. PMID: 15657077
    17. Binding of LPP and TRIP6 to Scrib links Scrib to a communication pathway between cell-cell contacts and the nucleus, and implicates these zyxin family members in Scrib-associated functions. PMID: 16137684
    18. The TRIP6 knock-down led to an increased number of longer stress fibers and to the induction of locomotive phenotype in carcinoma cells. PMID: 16240724
    19. AMPK phosphorylated TRIP6 in vitro at the N-terminus and the transcriptional co-activator properties of TRIP6 were enhanced by AMPK action. PMID: 16624523
    20. ZRP-1 plays a crucial role in coupling the cell-matrix/cell-cell-contact signals with Rho GTPase-mediated actin remodeling by localizing at cell-matrix and cell-cell contact sites. PMID: 17652164
    21. OIP-1 inhibits measles virus nucleocapsid protein induced pagetic osteoclast formation/activity through suppression of RANK signaling PMID: 18348201
    22. TRIP6 overexpression in colon tumors suggests its critical role in cancer progression. PMID: 19017743
    23. IL-12 stimulates the OIP-1 gene expression through STAT-3 activation in CD4+ T cells. PMID: 19259951
    24. Analysis of the subcellular distribution of ZRP-1 demonstrated that in the absence of endoglin, ZRP-1 mainly localizes to focal adhesion sites, whereas in the presence of endoglin ZRP-1 is found along actin stress fibers. PMID: 15148318

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus. Cytoplasm.
  • 蛋白家族:
    Zyxin/ajuba family
  • 組織特異性:
    Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors.
  • 數據庫鏈接:

    HGNC: 12311

    OMIM: 602933

    KEGG: hsa:7205

    STRING: 9606.ENSP00000200457

    UniGene: Hs.534360



主站蜘蛛池模板: 麻豆人妻少妇精品无码专区| 狠狠色噜噜狠狠狠888米奇| 下面一进一出好爽视频| 一区二区三区在线 | 欧| 国产在线观看超清无码视频一区二区 | 国产女主播喷水视频在线观看| 国产亚洲精品久久久久久打不开| 97人人添人澡人人爽超碰| 久久久综合九色合综| 国产乱子影视频上线免费观看| 国产乱人伦精品免费| 国产精品久久久久久久久久久久| 加比勒色综合久久| 内射一区二区精品视频在线观看 | 四虎永久在线精品无码视频| 亚洲一区波多野结衣在线| 国产产在线精品亚洲aavv| 欧美影院成年免费版| 亚洲人精品午夜射精日韩| 久久久亚洲欧洲日产国码αv| 久久久久影院美女国产主播| 国产欧美va天堂在线观看视频| 天天色影网| 亚洲色一色噜一噜噜噜| 啪一啪射一射插一插| 亚洲成a∨人片在线观看不卡| 国精品午夜福利视频不卡| aaa午夜级特黄日本大片| 最新在线精品国自产拍福利| 欧美精品高清在线观看| 国产在线精品99一卡2卡| 国产成人无码视频网站在线观看| 亚洲成a人片在线观看国产| 成人免费看www网址入口| 欧美中文字幕无线码视频| 久久精品99国产精品日本| 亚洲精品永久在线观看| 四虎影视国产精品久久| 西西艺术人像摄影| 裸身美女无遮挡永久免费视频 | 精品一卡2卡3卡4卡新区在线|