在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRIM35 Antibody

TRIM35 Antibody

  • 中文名稱：
    TRIM35兔多克隆抗體
  • 貨號：
    CSB-PA192313
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA192313(TRIM35 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A375 cells, human fetal muscle tissue, Primary antibody: CSB-PA192313(TRIM35 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    TRIM35
  • 別名：
    0710005M05Rik antibody; A430106H13Rik antibody; AW046487 antibody; Hemopoietic lineage switch protein 5 antibody; HLS5 antibody; KIAA1098 antibody; Macrophage derived apoptosis inducing RBCC protein antibody; MAIR antibody; MGC17233 antibody; mKIAA1098 antibody; NC8 antibody; Protein MAIR antibody; Protein Nc8 antibody; TRI35_HUMAN antibody; TRIM35 antibody; Tripartite motif containing 35 antibody; Tripartite motif containing protein 35 antibody; Tripartite motif-containing protein 35 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human TRIM35
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase that participates in multiple biological processes including cell death, glucose metabolism, and in particular, the innate immune response. Mediates 'Lys-63'-linked polyubiquitination of TRAF3 thereby promoting type I interferon production via DDX58/RIG-I signaling pathway. Can also catalyze 'Lys-48'-linked polyubiquitination and proteasomal degradation of viral proteins such as influenza virus PB2. Acts as a negative feedback regulator of TLR7- and TLR9-triggered signaling. Mechanistically, promotes the 'Lys-48'-linked ubiquitination of IRF7 and induces its degradation via a proteasome-dependent pathway. Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth.
  • 基因功能參考文獻：
    1. Authors subsequently investigated whether miR-4417 and TRIM35 regulate HCC cell proliferation and apoptosis through PKM2 Y105 phosphorylation, and the results supported our speculation that miR-4417 targets TRIM35 and regulates the Y105 phosphorylation of PKM2 to promote hepatocarcinogenesis. PMID: 28394882
    2. Data suggest that pyruvate kinase isoform M2 (PKM2)/tripartite motif-containing 35 (TRIM35) expression could be a biomarker for the prognosis of hepatocellular carcinoma (HCC) and target for cancer therapy. PMID: 25576919
    3. TRIM35 regulates the Warburg effect and tumorigenicity through interaction with PKM2 in hepatocellular carcinoma. PMID: 25263439
    4. gene located on chromosome 8p21, a region implicated in leukemias and solid tumors; enforced expression inhibited cell growth, clonogenicity, and tumorigenicity; conceivable HLS5 is one of the tumor suppressor genes thought to reside at the 8p21 locus PMID: 14662771
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    TRIM/RBCC family
  • 數據庫鏈接：

    HGNC: 16285

    OMIM: 617007

    KEGG: hsa:23087

    STRING: 9606.ENSP00000301924

    UniGene: Hs.104223



主站蜘蛛池模板： 成人性做爰aaa片免费| 国产一卡2卡3卡四卡精品app| 国产99久久久欧美黑人刘玥| 国产午夜福利片在线观看| √天堂中文www官网在线| 18禁黄网站禁片免费观看不卡| 国产内射一区亚洲| 露脸叫床粗话东北少妇| 国产亚洲精品美女久久久久| 亚洲一区二区无码偷拍| 国产精品久久久久久tv| 少妇人妻在线视频| 国产精品夜间视频香蕉| 动漫精品专区一区二区三区不卡| 蜜臀av国产精品久久久久| 国产香蕉尹人在线观看视频| 亚洲日韩中文字幕一区| 久久精品成人无码观看不卡| 亚洲综合网站久久久| 国产精品成人免费视频网站京东 | 亚洲国产制服丝袜高清在线| 精品久久综合1区2区3区激情| 国产色视频一区二区三区| 色哟哟在线视频精品一区| 国产成 人 综合 亚洲| 久久久精品人妻一区二区三区四| 少妇久久久久久久久久| 亚洲色无码专线精品观看| 亚洲精品久久av无码麻| 无码人妻少妇色欲av一区二区| 蜜桃av色偷偷av老熟女| 国产亚洲精品久久久久久无| 国内精品伊人久久久久网站| 无码一区二区三区亚洲人妻| 久久九九久精品国产| 国产成人片无码免费视频软件| 少妇又紧又深又湿又爽视频| 免费又黄又爽1000禁片| 精品国产av最大网站| 亚洲日韩亚洲另类| 少妇荡乳情欲办公室456视频|