在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRIM35 Antibody

TRIM35 Antibody

  • 中文名稱：
    TRIM35兔多克隆抗體
  • 貨號：
    CSB-PA434464
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA434464(TRIM35 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Hela cells, K562 cells, human fetal muscle tissue, A375 cells, hepg2 cells, Primary antibody: CSB-PA434464(TRIM35 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    TRIM35
  • 別名：
    0710005M05Rik antibody; A430106H13Rik antibody; AW046487 antibody; Hemopoietic lineage switch protein 5 antibody; HLS5 antibody; KIAA1098 antibody; Macrophage derived apoptosis inducing RBCC protein antibody; MAIR antibody; MGC17233 antibody; mKIAA1098 antibody; NC8 antibody; Protein MAIR antibody; Protein Nc8 antibody; TRI35_HUMAN antibody; TRIM35 antibody; Tripartite motif containing 35 antibody; Tripartite motif containing protein 35 antibody; Tripartite motif-containing protein 35 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human TRIM35
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase that participates in multiple biological processes including cell death, glucose metabolism, and in particular, the innate immune response. Mediates 'Lys-63'-linked polyubiquitination of TRAF3 thereby promoting type I interferon production via DDX58/RIG-I signaling pathway. Can also catalyze 'Lys-48'-linked polyubiquitination and proteasomal degradation of viral proteins such as influenza virus PB2. Acts as a negative feedback regulator of TLR7- and TLR9-triggered signaling. Mechanistically, promotes the 'Lys-48'-linked ubiquitination of IRF7 and induces its degradation via a proteasome-dependent pathway. Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth.
  • 基因功能參考文獻：
    1. Authors subsequently investigated whether miR-4417 and TRIM35 regulate HCC cell proliferation and apoptosis through PKM2 Y105 phosphorylation, and the results supported our speculation that miR-4417 targets TRIM35 and regulates the Y105 phosphorylation of PKM2 to promote hepatocarcinogenesis. PMID: 28394882
    2. Data suggest that pyruvate kinase isoform M2 (PKM2)/tripartite motif-containing 35 (TRIM35) expression could be a biomarker for the prognosis of hepatocellular carcinoma (HCC) and target for cancer therapy. PMID: 25576919
    3. TRIM35 regulates the Warburg effect and tumorigenicity through interaction with PKM2 in hepatocellular carcinoma. PMID: 25263439
    4. gene located on chromosome 8p21, a region implicated in leukemias and solid tumors; enforced expression inhibited cell growth, clonogenicity, and tumorigenicity; conceivable HLS5 is one of the tumor suppressor genes thought to reside at the 8p21 locus PMID: 14662771
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    TRIM/RBCC family
  • 數據庫鏈接：

    HGNC: 16285

    OMIM: 617007

    KEGG: hsa:23087

    STRING: 9606.ENSP00000301924

    UniGene: Hs.104223



主站蜘蛛池模板： 日韩人妻无码一区二区三区综合| 国产亚洲精品福利视频在线观看 | 尤物永久网站| 风韵少妇性饥渴推油按摩视频| 少妇荡乳情欲办公室456视频| 香蕉午夜福利院| 国产+日韩+另类+视频一区| 亚洲人成无码网站18禁10| 国产农村乱辈无码| 日本大香伊一区二区三区| 真实国产乱啪福利露脸| 国产欧美日韩综合精品二区| 国产69精品久久久久人妻刘玥 | 免费大片av手机看片不卡| 久久久久久夜精品精品免费啦| 韩国三级中文字幕hd| 日韩一区二区a片免费观看| 99精品久久久久久久婷婷| 国产精品无码综合区| 亚洲成av人片天堂网老年人| 精品亚洲国产成人av制服| 欧美日韩一区二区三区在线观看视频 | 国产精品福利视频萌白酱| 亚洲精品日韩一区二区小说| 狠狠综合久久久久尤物| 久久久久久久久毛片精品| 国产一区二区女内射| 偷看农村妇女牲交| 精品亚洲成a人片在线观看| 18禁美女裸体无遮挡免费观看国产| 豆国产95在线 | 亚洲| 成人片黄网站a毛片免费| 国产黄在线观看免费观看不卡| 国产成+人+综合+亚洲欧美| 无码精品黑人一区二区三区| 欧美人妻日韩精品| 18禁止进入1000部高潮网站| 日本毛茸茸的丰满熟妇| 亚洲精品久久久av无码专区| 大伊香蕉精品一区视频在线| 日产亚洲一区二区三区|