在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TRHR Antibody, Biotin conjugated

  • 中文名稱:
    TRHR兔多克隆抗體, Biotin偶聯(lián)
  • 貨號:
    CSB-PA024441LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TRHR Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    TRHR; Thyrotropin-releasing hormone receptor; TRH-R; Thyroliberin receptor
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Thyrotropin-releasing hormone receptor protein (320-398AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.
  • 基因功能參考文獻:
    1. These results demonstrate for the first time that not only agonist binding but also abundance of some signaling proteins may strongly affect TRH receptor dynamics in the plasma membrane PMID: 29137494
    2. a unique missense TRHR defect identified in a consanguineous family is associated with central hypothyroidism in homozygotes and hyperthyrotropinemia in heterozygotes, suggesting compensatory elevation of TSH with reduced biopotency; the I131T mutation decreases TRH binding and TRHR-Gq coupling and signaling PMID: 28419241
    3. rs16892496 polymorphism in the TRHR gene may play a role in FFM variation. PMID: 23543262
    4. The precoupling of receptors with their cognate G-proteins can contribute to faster G-protein activation and subsequent signal transfer into the cell interior. PMID: 22240728
    5. Data show that interactions of TRHR with GRKs and phosphatases are determined not simply by the amino acid sequences of the substrates, but by regions outside the cytoplasmic tails. PMID: 20345371
    6. A mutation in thyrotropin-releasing hormone receptor almost completely prevented receptor phosphorylation. PMID: 19906838
    7. TRH receptor in adenoma cells plays an important role in the paradoxical GH response to TRH administration in GH cell adenomas. PMID: 14599121
    8. after agonist-driven receptor internalization, the plasma membrane is replenished with younger receptors, arising either from an intracellular pool or preferential recycling of younger receptors. PMID: 15117874
    9. Controlled dimerization of the TRH receptor potentiates hormone-induced receptor trafficking. PMID: 16020481
    10. TRHR gene is an important gene for LBM variation. PMID: 19268274
    11. analysis of the effect of subcellular trafficking of the TRH receptor PMID: 19541745

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 12299

    OMIM: 188545

    KEGG: hsa:7201

    STRING: 9606.ENSP00000309818

    UniGene: Hs.3022



主站蜘蛛池模板: 一区二区狠狠色丁香久久婷婷| 国产精品毛片av在线看| 内射巨臀欧美在线视频| 亚洲欧洲日产国产 最新 | 亚洲一区二区三区含羞草| 久久99精品久久久久久| 国自产拍偷拍精品啪啪一区二区| 超碰色偷偷男人的天堂| 日本一道综合久久aⅴ免费| 国产成熟女人性满足视频| 国产亚洲精品字幕在线观看| 国产剧情国产精品一区| 欧美尺码专线欧洲b1b1| 四虎国产精品永久在线无码| 日韩av无码精品一二三区| 任我撸在线视频| av无码国产在线观看岛国| 制服丝袜亚洲中文欧美在线| 人妻中出受孕 中文字幕在线 | 黑人巨茎大战欧美白妇免费| 欧洲精品无码一区二区三区在线播放 | www国产亚洲精品久久网站| 亚洲制服丝中文字幕| 中文字幕精品一二三四五六七八| 欧美激情性做爰免费视频| 久热这里只精品99国产6-99re视…| 国产精品55夜色66夜色| 各种少妇正面bbw撒尿| 精品偷自拍另类在线观看 | 人摸人人人澡人人超碰97| 一二三四在线视频社区3| 99久久精品美女高潮喷水| 亚洲国产成人最新精品| 无码国模国产在线观看| 92久久精品一区二区| 人妻天天爽夜夜爽精品视频 | 免费无码一区二区三区a片百度 | 婷婷五月俺也去人妻| 涩涩鲁亚洲精品一区二区| 日日噜噜噜夜夜爽爽狠狠| 精品国产久九九|