在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TRHR Antibody, Biotin conjugated

  • 中文名稱:
    TRHR兔多克隆抗體, Biotin偶聯(lián)
  • 貨號:
    CSB-PA024441LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TRHR Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    TRHR; Thyrotropin-releasing hormone receptor; TRH-R; Thyroliberin receptor
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Thyrotropin-releasing hormone receptor protein (320-398AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.
  • 基因功能參考文獻:
    1. These results demonstrate for the first time that not only agonist binding but also abundance of some signaling proteins may strongly affect TRH receptor dynamics in the plasma membrane PMID: 29137494
    2. a unique missense TRHR defect identified in a consanguineous family is associated with central hypothyroidism in homozygotes and hyperthyrotropinemia in heterozygotes, suggesting compensatory elevation of TSH with reduced biopotency; the I131T mutation decreases TRH binding and TRHR-Gq coupling and signaling PMID: 28419241
    3. rs16892496 polymorphism in the TRHR gene may play a role in FFM variation. PMID: 23543262
    4. The precoupling of receptors with their cognate G-proteins can contribute to faster G-protein activation and subsequent signal transfer into the cell interior. PMID: 22240728
    5. Data show that interactions of TRHR with GRKs and phosphatases are determined not simply by the amino acid sequences of the substrates, but by regions outside the cytoplasmic tails. PMID: 20345371
    6. A mutation in thyrotropin-releasing hormone receptor almost completely prevented receptor phosphorylation. PMID: 19906838
    7. TRH receptor in adenoma cells plays an important role in the paradoxical GH response to TRH administration in GH cell adenomas. PMID: 14599121
    8. after agonist-driven receptor internalization, the plasma membrane is replenished with younger receptors, arising either from an intracellular pool or preferential recycling of younger receptors. PMID: 15117874
    9. Controlled dimerization of the TRH receptor potentiates hormone-induced receptor trafficking. PMID: 16020481
    10. TRHR gene is an important gene for LBM variation. PMID: 19268274
    11. analysis of the effect of subcellular trafficking of the TRH receptor PMID: 19541745

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 12299

    OMIM: 188545

    KEGG: hsa:7201

    STRING: 9606.ENSP00000309818

    UniGene: Hs.3022



主站蜘蛛池模板: 亲子乱子伦xxxx视频| 亚洲人成网网址在线看| 极品少妇的粉嫩小泬视频| 99久热在线精品视频观看| 99这里只有精品| 亚洲一卡一卡二新区无人区| 麻豆视传媒精品av| 久青草影院在线观看国产| 亚洲最大的熟女水蜜桃av网站| 99re在线播放| 日本熟妇人妻xxxx| 色妞色视频一区二区三区四区| 欧美老妇bbbwwbbbww| 一本一道色欲综合网| 亚洲欧洲日产国码无码| 国产精品久久久久久久久久| 女被男啪到哭的视频网站| 天天干天天日| 精品国产丝袜自在线拍国语| 超级大爆乳奶牛被调教出奶水| 亚洲人成图片小说网站| 免费看成人aa片无码视频羞羞网| 国产精品久久久久久影视| 狠狠cao2020高清视频| 真实国产精品视频400部| 久久精品亚洲精品无码| 婷婷色婷婷开心五月四房播播 | 国产精品人妻| 性欧美性另类巨大| 国产精品国产对白熟妇| 久久精品国产亚洲αv忘忧草| 色婷婷一区二区三区四区成人网 | 亚洲最大无码av网站观看| 日韩欧美亚洲综合久久影院| 欧美老妇与zozoz0交| 两个人日本www免费版| 精品无码久久久久国产电影| 国产三级a三级三级| 国产成人亚洲精品无码h在线| 亚洲人成在线观看网站不卡| 极品无码国模国产在线观看 |