在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TRAF3IP3 Antibody

  • 中文名稱:
    TRAF3IP3兔多克隆抗體
  • 貨號:
    CSB-PA794932
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from 293 cells, using T3JAM antibody.
    • Immunofluorescence analysis of HeLa cells, using T3JAM antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TRAF3IP3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TRAF3IP3
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from internal of Human T3JAM.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IF
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
    IF 1:100-1:500
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Adapter protein that plays essential roles in both innate and adaptive immunity. Plays a crucial role in the regulation of thymocyte development. Mechanistically, mediates TCR-stimulated activation through recruiting MAP2K1/MEK1 to the Golgi and, thereby, facilitating the interaction of MAP2K1/MEK1 with its activator BRAF. Plays also an essential role in regulatory T-cell stability and function by recruiting the serine-threonine phosphatase catalytic subunit (PPP2CA) to the lysosome, thereby facilitating the interaction of PP2Ac with the mTORC1 component RPTOR and restricting glycolytic metabolism. Positively regulates TLR4 signaling activity in macrophage-mediated inflammation by acting as a molecular clamp to facilitate LPS-induced translocation of TLR4 to lipid rafts. In response to viral infection, facilitates the recruitment of TRAF3 to MAVS within mitochondria leading to IRF3 activation and interferon production. However, participates in the maintenance of immune homeostasis and the prevention of overzealous innate immunity by promoting 'Lys-48'-dependent ubiquitination of TBK1.
  • 基因功能參考文獻:
    1. This paper provides an alignment of the mouse and human proteins. PMID: 14572659
    2. TRAF3IP3 stimulated cell growth by modulating the c-Jun N-terminal kinase (JNK) pathway PMID: 17868742
  • 亞細胞定位:
    Cell membrane. Golgi apparatus membrane; Single-pass type IV membrane protein. Lysosome membrane. Mitochondrion outer membrane.
  • 數據庫鏈接:

    HGNC: 30766

    OMIM: 608255

    KEGG: hsa:80342

    STRING: 9606.ENSP00000355991

    UniGene: Hs.147434



主站蜘蛛池模板: 极品少妇被猛得白浆直喷白浆小说 | 亚洲国产精品高清久久久| 天天槽夜夜槽槽不停| 亚洲毛片多多影院| 亚洲精品无码不卡在线播he| 少妇与黑人一二三区无码| 久久婷婷大香萑太香蕉av人| 欧美日产成人高清视频| 秋霞特色aa大片| 亚欧成a人无码精品va片| 国产情侣疯狂作爱系列| 亚洲综合日韩av无码毛片| 欧美牲交a欧美牲交aⅴ免费真| 国产精品成人网站| 97久久久人妻一区精品| 中文字幕精品视频在线看免费| 午夜福利av无码一区二区| 大肉大捧一进一出好爽视频| 亚洲aⅴ综合色区无码一区| 2021少妇久久久久久久久久| 久久精品女人天堂av免费观看| 色一情一区二区三区四区| 国产免费爽爽视频| 亚洲欧美中文高清在线专区| 国产精品涩涩涩视频网站| 国产成人av一区二区三区在线| 亚洲欧美综合一区二区三区| 国产精品18禁污污网站| 国产成人艳妇aa视频在线| 在线综合亚洲欧洲综合网站| 一区二区三区毛aaaa片特级| 国产又大又硬又粗| 国产人妻黑人一区二区三区| 日本高清在线天码一区播放| 国精一二二产品无人区免费应用 | 亚洲熟妇无码八av在线播放| 天堂√最新版中文在线天堂| 日韩欧美激情兽交| 国产精品伦一区二区三级视频| 无码精品a∨在线观看无广告| 麻豆精品偷拍人妻在线网址|