在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TRAF3IP3 Antibody, Biotin conjugated

  • 中文名稱:
    TRAF3IP3兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA896865LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TRAF3IP3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TRAF3IP3
  • 別名:
    TRAF3IP3 antibody; T3JAM antibody; TRAF3-interacting JNK-activating modulator antibody; TRAF3-interacting protein 3 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human TRAF3-interacting JNK-activating modulator protein (74-185AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Adapter protein that plays essential roles in both innate and adaptive immunity. Plays a crucial role in the regulation of thymocyte development. Mechanistically, mediates TCR-stimulated activation through recruiting MAP2K1/MEK1 to the Golgi and, thereby, facilitating the interaction of MAP2K1/MEK1 with its activator BRAF. Plays also an essential role in regulatory T-cell stability and function by recruiting the serine-threonine phosphatase catalytic subunit (PPP2CA) to the lysosome, thereby facilitating the interaction of PP2Ac with the mTORC1 component RPTOR and restricting glycolytic metabolism. Positively regulates TLR4 signaling activity in macrophage-mediated inflammation by acting as a molecular clamp to facilitate LPS-induced translocation of TLR4 to lipid rafts. In response to viral infection, facilitates the recruitment of TRAF3 to MAVS within mitochondria leading to IRF3 activation and interferon production. However, participates in the maintenance of immune homeostasis and the prevention of overzealous innate immunity by promoting 'Lys-48'-dependent ubiquitination of TBK1.
  • 基因功能參考文獻:
    1. This paper provides an alignment of the mouse and human proteins. PMID: 14572659
    2. TRAF3IP3 stimulated cell growth by modulating the c-Jun N-terminal kinase (JNK) pathway PMID: 17868742
  • 亞細胞定位:
    Cell membrane. Golgi apparatus membrane; Single-pass type IV membrane protein. Lysosome membrane. Mitochondrion outer membrane.
  • 數據庫鏈接:

    HGNC: 30766

    OMIM: 608255

    KEGG: hsa:80342

    STRING: 9606.ENSP00000355991

    UniGene: Hs.147434



主站蜘蛛池模板: 四虎永久在线精品8848a| 国产内射老熟女aaaa∵| 野花社区在线www日本| 国产av亚洲精品ai换脸电影| 国产精品∧v在线观看| 人妻丰满熟妇av无码区乱 | 欧美日韩国产免费一区二区三区 | www婷婷av久久久影片| 国产成人综合久久亚洲精品| 精品视频一区二区三区中文字幕 | 国产欧美成人xxx视频| 午夜人妻理论片天堂影院| 在线观看午夜亚洲一区| 国语精品一区二区三区| 性欧美性另类巨大| 未满十八18禁止午夜免费网站| 亚洲精品久久久久国产| 老子午夜精品无码不卡 | 精品夜夜澡人妻无码av| 色欲人妻aaaaaa无码| 国产精品va在线播放| 欧美变态另类刺激| 国产99视频精品免费视看9| 少妇熟女久久综合网色欲| 在线观看国产亚洲视频免费| 97人妻人人做人碰人人爽| 国产精品无码一区二区在线a片| 精品无码国产自产在线观看水浒传 | 国产精品久久久亚洲| 西西人体大胆啪啪实拍| 国产精品久久久久影院色| 国产免费无遮挡吸乳视频| 国产欲女高潮正在播放| 免费国产精品视频在线| 粉色午夜视频| 蜜臀av色欲a片无码精品一区| 人人狠狠久久亚洲综合88| 久久综合九色综合国产| 亚洲精品喷潮一区二区三区 | 亚洲欧美色中文字幕在线| 无码中文字幕日韩专区|