在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TPM4 Antibody

TPM4 Antibody

  • 中文名稱：
    TPM4兔多克隆抗體
  • 貨號：
    CSB-PA024108GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    epididymis secretory protein Li 108 antibody; HEL-S-108 antibody; TM30p1 antibody; TMP 4 antibody; TPM4 antibody; TPM4_HUMAN antibody; Tropomyosin 4 antibody; Tropomyosin alpha 4 chain antibody; Tropomyosin alpha-4 chain antibody; Tropomyosin-4 antibody; wu:fb06e07 antibody; zgc:103436 antibody; zgc:63909 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human TPM4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
  • 基因功能參考文獻(xiàn)：
    1. TPM4 is associated with clinical progression in colon cancer patients and acts as a tumor suppressor in colon cancer cells. PMID: 29455030
    2. Tpm4.1 is essential to maintain cell-cell adhesions and to inhibit abnormal increases in cell migration and invasion, which are important to prevent invasion and metastasis of breast cancer cells. PMID: 28431393
    3. findings demonstrate a nonredundant role for TPM4 in platelet biogenesis in humans and mice and reveal that truncating variants in TPM4 cause a previously undescribed dominant Mendelian platelet disorder. PMID: 28134622
    4. Results show that Tpm4.2 facilitates the transition of NM-2A to the strongly actin-binding myosin-ADP state. PMID: 26847712
    5. Data indicate the upregulation of tropomyosin-4 in infiltrating ductal breast carcinomas (IDCAs) tissues, which may suggest its involvement in breast cancer development. PMID: 23812729
    6. TPM4, PDIA and SRC8 were also localized to the trophoblast cells, further highlighting the importance of these cytoskeletal remodelling proteins in early pregnancy PMID: 21373848
    7. Low TPM4 expression in the cytoplasm is associated with uterine cervix carcinogenesis. PMID: 21119665
    8. Tm4-defined cytoskeleton is a marker of growth and repair/regeneration in response to injury, disease state and stress in skeletal muscle. PMID: 17968984

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Tropomyosin family
  • 組織特異性：
    Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets o
  • 數(shù)據(jù)庫鏈接：

    HGNC: 12013

    OMIM: 600317

    KEGG: hsa:7171

    UniGene: Hs.631618



主站蜘蛛池模板： 青乐娱精品视频一国产分类| 激情国产av做激情国产爱| 亚洲国产综合在线观看不卡| 国产精品第一区揄拍无码| 伊人色合天天久久综合网| 成人综合婷婷国产精品久久蜜臀| 色av综合av综合无码网站| 免费国产va在线观看| 国产av中文av无码av狼人| 国产成人精品免费视频大全软件 | 妲己丰满人熟妇大尺度人体艺| 国产人妻一区二区三区四区五区六| 两个黑人大战嫩白金发美女| 欧美性猛交xxxx免费看| 国产亚洲中文日韩欧美综合网| 色香阁综合无码国产在线| 国产伦精品一区二区三区免.费 | 久久综合色之久久综合| 久久午夜夜伦鲁鲁片免费无码影视 | 国色天香天天影院综合网| 中文字幕乱码久久午夜不卡| 亚洲熟妇av综合网五月| 国产后入又长又硬| 亚洲精品www久久久久久| 丝袜美腿丝袜亚洲综合| 香蕉97超级碰碰碰免费公开| 无码加勒比一区二区三区四区| 一本加勒比波多野结衣| 老外和中国女人毛片免费视频| 免费人成视频网站在线观看18| 92国产精品午夜福利无毒不卡| 熟妇高潮精品一区二区三区| 国产又黄又爽又猛免费视频播放| 久久亚洲精品高潮综合色a片| 无码日韩人妻av一区免费| 久久av无码精品人妻系列试探| 一个人在线观看免费中文www| 99在线精品一区二区三区| 国产亚洲中文字幕在线制服| 丰满熟女人妻一区二区三| 全部孕妇毛片|