在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TPM4 Antibody

TPM4 Antibody

  • 中文名稱：
    TPM4兔多克隆抗體
  • 貨號：
    CSB-PA024108GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    epididymis secretory protein Li 108 antibody; HEL-S-108 antibody; TM30p1 antibody; TMP 4 antibody; TPM4 antibody; TPM4_HUMAN antibody; Tropomyosin 4 antibody; Tropomyosin alpha 4 chain antibody; Tropomyosin alpha-4 chain antibody; Tropomyosin-4 antibody; wu:fb06e07 antibody; zgc:103436 antibody; zgc:63909 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human TPM4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
  • 基因功能參考文獻(xiàn)：
    1. TPM4 is associated with clinical progression in colon cancer patients and acts as a tumor suppressor in colon cancer cells. PMID: 29455030
    2. Tpm4.1 is essential to maintain cell-cell adhesions and to inhibit abnormal increases in cell migration and invasion, which are important to prevent invasion and metastasis of breast cancer cells. PMID: 28431393
    3. findings demonstrate a nonredundant role for TPM4 in platelet biogenesis in humans and mice and reveal that truncating variants in TPM4 cause a previously undescribed dominant Mendelian platelet disorder. PMID: 28134622
    4. Results show that Tpm4.2 facilitates the transition of NM-2A to the strongly actin-binding myosin-ADP state. PMID: 26847712
    5. Data indicate the upregulation of tropomyosin-4 in infiltrating ductal breast carcinomas (IDCAs) tissues, which may suggest its involvement in breast cancer development. PMID: 23812729
    6. TPM4, PDIA and SRC8 were also localized to the trophoblast cells, further highlighting the importance of these cytoskeletal remodelling proteins in early pregnancy PMID: 21373848
    7. Low TPM4 expression in the cytoplasm is associated with uterine cervix carcinogenesis. PMID: 21119665
    8. Tm4-defined cytoskeleton is a marker of growth and repair/regeneration in response to injury, disease state and stress in skeletal muscle. PMID: 17968984

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Tropomyosin family
  • 組織特異性：
    Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets o
  • 數(shù)據(jù)庫鏈接：

    HGNC: 12013

    OMIM: 600317

    KEGG: hsa:7171

    UniGene: Hs.631618



主站蜘蛛池模板： 手机在线看永久av片免费| 亚洲国产成人极品综合| 久久青青草原国产最新片完整| 国产大量精品视频网站| 久久精品人妻中文系列| 无码国产精品一区二区免费i6| 国产suv精品一区二区五| 99久久精品无码一区二区毛片| 性色欲情网站| 中日韩va无码中文字幕| 久久精品国产精品国产精品污| 亚洲中文字幕无码一区二区三区 | 日韩高清在线观看永久| 女人夜夜春精品a片| 一区二区国产精品精华液| 中文字幕一二三区波多野结衣| 国产精品久免费的黄牛仔短裤| 成人精品v视频在线| 国产精品成人av在线观看春天| 四虎亚洲欧美成人网站| 国语自产免费精品视频在| 人妻无码av中文系列久| 精品熟女少妇av免费久久| 久久国产劲爆∧v内射-百度 | 中文字幕日本六区小电影| 欧美日韩国产一区二区三区不卡 | 日本真人边吃奶边做爽电影| 色噜噜一区二区三区| 亚洲精品一区二区三区婷婷月| 国产精品jk白丝在线播放| 尤物精品国产第一福利网站| 无码人妻精品一区二区三区在线 | 超碰97人人让你爽| 青草青草视频2免费观看| 午夜福利理论片在线观看播放| 久久精品国产精品亚洲下载| 国产美女视频国产视视频| 男人j进女人p免费视频| 亚洲日本中文字幕天天更新| 久久青青草原国产精品最新片 | 四虎永久在线精品免费视频观看|