在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Human Tropomyosin alpha-4 chain(TPM4) ELISA kit

Human Tropomyosin alpha-4 chain(TPM4) ELISA kit

  • 中文名稱：
    人原肌球蛋白α4(TPM4)酶聯免疫試劑盒
  • 貨號：
    CSB-EL024108HU
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    人原肌球蛋白α4(TPM4)酶聯免疫試劑盒（CSB-EL024108HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿、細胞裂解物樣本中的TPM4含量。試劑盒檢測范圍為23.5 pg/mL-1500 pg/mL，適用于基礎科研中TPM4蛋白表達水平的定量分析，包括但不限于腫瘤細胞侵襲轉移機制研究、心肌功能異常模型分析、骨骼肌疾病病理探索，以及細胞骨架動態變化或相關信號通路的功能研究。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    epididymis secretory protein Li 108 ELISA Kit; HEL-S-108 ELISA Kit; TM30p1 ELISA Kit; TMP 4 ELISA Kit; TPM4 ELISA Kit; TPM4_HUMAN ELISA Kit; Tropomyosin 4 ELISA Kit; Tropomyosin alpha 4 chain ELISA Kit; Tropomyosin alpha-4 chain ELISA Kit; Tropomyosin-4 ELISA Kit; wu:fb06e07 ELISA Kit; zgc:103436 ELISA Kit; zgc:63909 ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates, cell lysates
  • 檢測范圍：
    23.5 pg/mL-1500 pg/mL
  • 靈敏度：
    5.8 pg/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Signal Transduction
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human TPM4 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %100
    Range %97-103
    1:2Average %85
    Range %81-89
    1:4Average %91
    Range %85-97
    1:8Average %99
    Range %95-104
  • 回收率：
    The recovery of human TPM4 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 8782-90
    EDTA plasma (n=4)9490-98
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    15002.557 2.597 2.577 2.398
    7501.916 1.936 1.926 1.747
    3751.278 1.298 1.288 1.109
    187.50.798 0.742 0.770 0.591
    940.481 0.499 0.490 0.311
    470.367 0.355 0.361 0.182
    23.50.264 0.268 0.266 0.087
    00.178 0.179 0.179
  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 功能：
    Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
  • 基因功能參考文獻：
    1. TPM4 is associated with clinical progression in colon cancer patients and acts as a tumor suppressor in colon cancer cells. PMID: 29455030
    2. Tpm4.1 is essential to maintain cell-cell adhesions and to inhibit abnormal increases in cell migration and invasion, which are important to prevent invasion and metastasis of breast cancer cells. PMID: 28431393
    3. findings demonstrate a nonredundant role for TPM4 in platelet biogenesis in humans and mice and reveal that truncating variants in TPM4 cause a previously undescribed dominant Mendelian platelet disorder. PMID: 28134622
    4. Results show that Tpm4.2 facilitates the transition of NM-2A to the strongly actin-binding myosin-ADP state. PMID: 26847712
    5. Data indicate the upregulation of tropomyosin-4 in infiltrating ductal breast carcinomas (IDCAs) tissues, which may suggest its involvement in breast cancer development. PMID: 23812729
    6. TPM4, PDIA and SRC8 were also localized to the trophoblast cells, further highlighting the importance of these cytoskeletal remodelling proteins in early pregnancy PMID: 21373848
    7. Low TPM4 expression in the cytoplasm is associated with uterine cervix carcinogenesis. PMID: 21119665
    8. Tm4-defined cytoskeleton is a marker of growth and repair/regeneration in response to injury, disease state and stress in skeletal muscle. PMID: 17968984

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Tropomyosin family
  • 組織特異性：
    Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets o
  • 數據庫鏈接：

    HGNC: 12013

    OMIM: 600317

    KEGG: hsa:7171

    UniGene: Hs.631618



主站蜘蛛池模板： 亚洲日韩性欧美中文字幕| 国产精品久免费的黄牛仔短裤| 影音先锋中文无码一区| 50岁熟妇的呻吟声对白| 饥渴少妇高潮视频大全| 极品美女扒开粉嫩小泬图片| 水蜜桃亚洲一二三四在线| 欧洲精品码一区二区三区| 日韩乱码人妻无码系列中文字幕 | 亚洲国产成人精品无码区蜜柚| 亚洲欧美日韩国产国产a| 国产xxxx99真实实拍| 欧美性生交大片18禁止| 久在线精品视频线观看| 辽宁熟女高潮狂叫视频| 羞羞影院午夜男女爽爽| 精品97国产免费人成视频| 小sao货水好多真紧h视频| 狠狠躁夜夜躁人人爽蜜桃| 日本人妻中文字幕乱码系列| 国产精品人妻在线观看| 国产精品人人做人人爽| 人妻少妇精品无码专区| 国产精品毛片完整版视频| 国产午夜亚洲精品理论片不卡| 亚洲老熟女与小伙bbwtv| 天天躁日日躁狠狠躁欧美老妇 | 国产又滑又嫩又白| 日本精品一区二区三区四区| 精品一区二区国产在线观看 | 粉嫩av久久一区二区三区| 午夜裸体性播放| 99国产在线精品视频| 免费不卡无码av在线观看| 精品人妻av区波多野结衣| 国内精品人妻久久毛片app| 大陆精大陆国产国语精品| 涩里番网污站| 国产高清乱理伦片中文小说| 大陆熟妇丰满多毛xxxx| 国语精品福利自产拍在线观看|