在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TONSL Antibody

TONSL Antibody

  • 中文名稱：
    TONSL兔多克隆抗體
  • 貨號：
    CSB-PA836224LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA836224LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TONSL Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TONSL
  • 別名：
    I kappa B related protein antibody; I-kappa-B-related protein antibody; IkappaBR antibody; IKBR antibody; Inhibitor of kappa B related protein antibody; Inhibitor of kappa B-related protein antibody; MMS22L-interacting protein antibody; MMS22L-interacting protein, NFBIL2/TONSL antibody; NF kappa B inhibitor like protein 2 antibody; NF-kappa-B inhibitor-like protein 2 antibody; NFBIL2 antibody; NFBIL2/TONSL antibody; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like protein 2 antibody; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 antibody; Protein IkappaBR antibody; Tonsl antibody; TONSL_HUMAN antibody; Tonsoku-like protein antibody; tonsoku-like, DNA repair protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Tonsoku-like protein (668-955AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，TONSL Antibody (CSB-PA836224LA01HU)，的標記方式是Non-conjugated。對于TONSL Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA836224LB01HU TONSL Antibody, HRP conjugated ELISA
    FITC CSB-PA836224LC01HU TONSL Antibody, FITC conjugated
    Biotin CSB-PA836224LD01HU TONSL Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, may act as a scaffold.
  • 基因功能參考文獻：
    1. By specifically regulating RAD51 activity at uncoupled replication forks, MMS22L-TONSL stabilizes perturbed replication forks by promoting replication fork reversal and stimulating their homologous recombination-mediated restart in vivo. PMID: 27797818
    2. new histones incorporated during DNA replication provide a signature of post-replicative chromatin, read by the human TONSL-MMS22L homologous recombination complex PMID: 27338793
    3. Common NFKBIL2 polymorphisms are associated with susceptibility to invasive pneumococcal infection. PMID: 21171993
    4. Results strongly suggest that the Mms22L-Nfkbil2 complex contributes to genome stability by regulating the chromatin state at stalled replication forks. PMID: 21113133
    5. These results indicate that MMS22L and TONSL are genome caretakers that stimulate the recombination-dependent repair of stalled or collapsed replication forks. PMID: 21055983
    6. MMS22L and TONSL are required for the maintenance of genome stability. PMID: 21055984
    7. This study identifies MMS22L-NFKBIL2 as components of the replication stress control pathway. PMID: 21055985

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Note=Mainly nuclear. Localizes to DNA damage sites, accumulates at stressed replication forks.
  • 蛋白家族：
    Tonsoku family
  • 組織特異性：
    Expressed in heart, skeletal muscle and tracheal epithelial cells.
  • 數據庫鏈接：

    HGNC: 7801

    OMIM: 604546

    KEGG: hsa:4796

    STRING: 9606.ENSP00000386239

    UniGene: Hs.675285



主站蜘蛛池模板： 人妻精品动漫h无码网站| 俺去俺来也在线www色官网| 天堂va蜜桃一区二区三区| 久久精品成人免费国产| 亚洲 欧洲 日韩 综合色天使| 国内嫩模私拍精品视频| 少妇被猛男粗大的猛进出| 国产极品精品自在线| 伦理片无码电影在线看| av无码免费永久在线观看| 国内a∨免费播放| 大香伊蕉国产av| 国产成人精品午夜福利在线播放 | 成人性生交大片免费卡看| 亚洲成av人片在线观看| 中文字幕日产熟女乱码| 中文字幕在线不卡精品视频99 | 国产精品爽爽久久久久久| √天堂资源地址在线官网| 久热这里只有精品99在线观看| av制服丝袜白丝国产网站| 欧美成人在线视频| 高清破外女出血av毛片| 2020国产激情视频在线观看| 精品无码久久久久久久久久| 狂野欧美性猛xxxx乱大交| 久久99国产综合精品女同| 久久99国产精品久久| 亚洲欧洲免费无码| 天天澡天天揉揉av在线| 精品无人区麻豆乱码1区2区| 亚洲精品成人网站在线观看| 无码av免费精品一区二区三区| 在线观看一区二区三区国产免费 | 真人与拘做受免费视频| 国产高清亚洲精品视bt天堂频| 成人a片产无码免费视频在线观看| 鲁鲁狠狠狠7777一区二区| 亚洲国产一区二区三区| 成在人线av无码免费高潮喷水 | 无尺码精品产品网站|