在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TONSL Antibody

TONSL Antibody

  • 中文名稱：
    TONSL兔多克隆抗體
  • 貨號：
    CSB-PA836224LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA836224LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TONSL Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TONSL
  • 別名：
    I kappa B related protein antibody; I-kappa-B-related protein antibody; IkappaBR antibody; IKBR antibody; Inhibitor of kappa B related protein antibody; Inhibitor of kappa B-related protein antibody; MMS22L-interacting protein antibody; MMS22L-interacting protein, NFBIL2/TONSL antibody; NF kappa B inhibitor like protein 2 antibody; NF-kappa-B inhibitor-like protein 2 antibody; NFBIL2 antibody; NFBIL2/TONSL antibody; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like protein 2 antibody; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 antibody; Protein IkappaBR antibody; Tonsl antibody; TONSL_HUMAN antibody; Tonsoku-like protein antibody; tonsoku-like, DNA repair protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Tonsoku-like protein (668-955AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，TONSL Antibody (CSB-PA836224LA01HU)，的標記方式是Non-conjugated。對于TONSL Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA836224LB01HU TONSL Antibody, HRP conjugated ELISA
    FITC CSB-PA836224LC01HU TONSL Antibody, FITC conjugated
    Biotin CSB-PA836224LD01HU TONSL Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, may act as a scaffold.
  • 基因功能參考文獻：
    1. By specifically regulating RAD51 activity at uncoupled replication forks, MMS22L-TONSL stabilizes perturbed replication forks by promoting replication fork reversal and stimulating their homologous recombination-mediated restart in vivo. PMID: 27797818
    2. new histones incorporated during DNA replication provide a signature of post-replicative chromatin, read by the human TONSL-MMS22L homologous recombination complex PMID: 27338793
    3. Common NFKBIL2 polymorphisms are associated with susceptibility to invasive pneumococcal infection. PMID: 21171993
    4. Results strongly suggest that the Mms22L-Nfkbil2 complex contributes to genome stability by regulating the chromatin state at stalled replication forks. PMID: 21113133
    5. These results indicate that MMS22L and TONSL are genome caretakers that stimulate the recombination-dependent repair of stalled or collapsed replication forks. PMID: 21055983
    6. MMS22L and TONSL are required for the maintenance of genome stability. PMID: 21055984
    7. This study identifies MMS22L-NFKBIL2 as components of the replication stress control pathway. PMID: 21055985

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Note=Mainly nuclear. Localizes to DNA damage sites, accumulates at stressed replication forks.
  • 蛋白家族：
    Tonsoku family
  • 組織特異性：
    Expressed in heart, skeletal muscle and tracheal epithelial cells.
  • 數據庫鏈接：

    HGNC: 7801

    OMIM: 604546

    KEGG: hsa:4796

    STRING: 9606.ENSP00000386239

    UniGene: Hs.675285



主站蜘蛛池模板： 亚洲欧洲免费无码| 免费人成视频在线播放视频| 69国产成人精品午夜福中文 | 色妞色视频一区二区三区四区| 亚洲人成无码区在线观看| 日韩精品亚洲aⅴ在线影院| 97久久超碰国产精品旧版麻豆| 欧美老熟妇乱子| 国产欧美一区二区精品性色| 女人被狂躁60分钟视频 | 东北老女人高潮大叫对白| 一本大道无码人妻精品专区| 校园春色~综合网| 青青草国产精品免费观看| 无码熟妇人妻av在线网站| 国产精品丝袜高跟鞋| 波多野结衣办公室双飞| 久久久久国产一区二区| 国产精品高潮露脸在线观看| 色噜噜狠狠成人中文综合| 无码国产精品一区二区免费模式| 日日橹狠狠爱欧美超碰 | 精品乱码一区二区三四区视频| 男女裸体下面进入的免费视频| 精品久久国产综合婷婷五月| 欧洲美熟女乱又伦av| 成年女人免费碰碰视频| 国产aⅴ激情无码久久久无码| 亚洲爆乳成av人在线蜜芽| 欧美天天综合色影久久精品| 精品av无码国产一区二区| 国产xxxx做受性欧美88| 国产精品夜夜春夜夜爽久久| 免费无码又爽又黄又刺激网站| 波多野结衣在线播放| 无码欧美黑人xxx一区二区三区| 日韩精品一卡2卡3卡4卡新区| 日韩欧美亚洲综合久久影院| 特大巨黑吊xxxx高潮| 在线 | 麻豆国产传媒61国产免费 视频在线+欧美十亚洲曰本 | 亚洲a∨无码无在线观看|