在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TKT Antibody

TKT Antibody

  • 中文名稱：
    TKT兔多克隆抗體
  • 貨號：
    CSB-PA570820
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA570820(TKT Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA570820(TKT Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    EC 2.2.1.1 antibody; FLJ34765 antibody; TK antibody; TKT 1 antibody; tkt antibody; TKT_HUMAN antibody; TKT1 antibody; Transketolase (Wernicke Korsakoff syndrome) antibody; Transketolase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human TKT
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  • 基因功能參考文獻：
    1. Over-expressed and hypo-methylated TKT gene is associated with hepatocellular carcinoma. PMID: 27760737
    2. The observed associations of genetic variation in transketolase enzyme with neuropathic symptoms and reduced thermal sensation in recent-onset diabetes suggest a role of pathways metabolizing glycolytic intermediates in early diabetic neuropathy. PMID: 27103086
    3. reduced expression of transketolase in pyrimidine 5'-nucleotidase deficient patients PMID: 27381654
    4. Mutations in TKT gene is associated with a Syndrome Including Short Stature, Developmental Delay, and Congenital Heart Defects. PMID: 27259054
    5. transketolase (TKT)is required for cancer growth because of its ability to affect the production of NAPDH to counteract oxidative stress. PMID: 26811478
    6. Transketolase is upregulated in metastatic peritoneal implants and promotes ovarian cancer cell proliferation. PMID: 25895698
    7. Akt1 phosphorylates TKT on Thr382, markedly enhancing enzyme activity. PMID: 24981175
    8. TKT rs3736156 identified significant differences in the onset of cardiovascular event in patients having genotypes AG + AA versus GG PMID: 23492569
    9. basal TK activity was decreased in cases with diabetic neuropathy PMID: 24114639
    10. Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme. PMID: 22645655
    11. Data indicate that transketolase (hTKT). shares 61% sequence identity with transketolase-like protein (TKTL1). PMID: 23261987
    12. No transketolase activity of TKTDelta38 can be detected for conversion of physiological sugar substrates thus arguing against an intrinsically encoded enzymatic function of TKTL1 in tumor cell metabolism PMID: 23118983
    13. TKT is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
    14. Single Nucleotide Polymorphism in transketolase is associated with diabetic nephropathy. PMID: 20826743
    15. The crystal structure of human transketolase and new insights into its mode of action. PMID: 20667822
    16. Almost all multiple sclerosis patients had cerebrospinal fluid IgG directed to isoforms of one of the oligodendroglial molecules, transketolase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase type I, collapsin response mediator protein 2, and tubulin beta4. PMID: 18676363

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Short stature, developmental delay, and congenital heart defects (SDDHD)
  • 蛋白家族：
    Transketolase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11834

    OMIM: 606781

    KEGG: hsa:7086

    STRING: 9606.ENSP00000405455

    UniGene: Hs.89643



主站蜘蛛池模板： 韩国精品久久久久久无码 | 精品人妻系列无码人妻免费视频| 日韩去日本高清在线| 三个男人躁我一个爽视频免费| 新版天堂资源中文8在线| 香港三日本8a三级少妇三级99| 亚洲精品卡2卡3卡4卡5卡区| 国产区精品一区二区不卡中文| 亚洲精品久久婷婷丁香51| 日韩人妻一区二区三区免费| 欧美成人精品高清在线播放| 成年女人看片永久免费视频 | 无码少妇精品一区二区免费动态| 欧美精品videossex另类日本 | 狂野欧美激情性xxxx| 亚洲国产成人av在线观看| 国产巨大爆乳在线观看| 欧洲美女黑人粗性暴交| 亚洲综合无码一区二区| 国产乱子伦精品免费无码专区| 日韩视频无码免费一区=区三区| 国产精品久久久久久人妻精品| 人妻熟女αⅴ一区二区三区| 怡春院久久国语视频免费| 亚洲国产日韩a在线播放| 一个人看的www片免费高清视频| 久久久www成人免费精品| 少妇性荡欲视频| 久久国产精品成人片免费| 可以看三级的网站| 日本熟妇浓密毛毛多| 韩国主播av福利一区二区| 中文字幕日韩一区二区三区不卡| 欧美网站免费观看在线| 制服丝袜亚洲中文欧美在线| 亚洲熟妇少妇任你躁在线观看无码| 国产精品一国产精品| 最新69成人精品视频免费| 无码国产精品久久一区免费| 97一区二区国产好的精华液| 日本一区二区三区不卡免费|