在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TKT Antibody

  • 中文名稱:
    TKT兔多克隆抗體
  • 貨號:
    CSB-PA025245
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA025245(TKT Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA025245(TKT Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    EC 2.2.1.1 antibody; FLJ34765 antibody; TK antibody; TKT 1 antibody; tkt antibody; TKT_HUMAN antibody; TKT1 antibody; Transketolase (Wernicke Korsakoff syndrome) antibody; Transketolase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human TKT
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  • 基因功能參考文獻:
    1. Over-expressed and hypo-methylated TKT gene is associated with hepatocellular carcinoma. PMID: 27760737
    2. The observed associations of genetic variation in transketolase enzyme with neuropathic symptoms and reduced thermal sensation in recent-onset diabetes suggest a role of pathways metabolizing glycolytic intermediates in early diabetic neuropathy. PMID: 27103086
    3. reduced expression of transketolase in pyrimidine 5'-nucleotidase deficient patients PMID: 27381654
    4. Mutations in TKT gene is associated with a Syndrome Including Short Stature, Developmental Delay, and Congenital Heart Defects. PMID: 27259054
    5. transketolase (TKT)is required for cancer growth because of its ability to affect the production of NAPDH to counteract oxidative stress. PMID: 26811478
    6. Transketolase is upregulated in metastatic peritoneal implants and promotes ovarian cancer cell proliferation. PMID: 25895698
    7. Akt1 phosphorylates TKT on Thr382, markedly enhancing enzyme activity. PMID: 24981175
    8. TKT rs3736156 identified significant differences in the onset of cardiovascular event in patients having genotypes AG + AA versus GG PMID: 23492569
    9. basal TK activity was decreased in cases with diabetic neuropathy PMID: 24114639
    10. Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme. PMID: 22645655
    11. Data indicate that transketolase (hTKT). shares 61% sequence identity with transketolase-like protein (TKTL1). PMID: 23261987
    12. No transketolase activity of TKTDelta38 can be detected for conversion of physiological sugar substrates thus arguing against an intrinsically encoded enzymatic function of TKTL1 in tumor cell metabolism PMID: 23118983
    13. TKT is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
    14. Single Nucleotide Polymorphism in transketolase is associated with diabetic nephropathy. PMID: 20826743
    15. The crystal structure of human transketolase and new insights into its mode of action. PMID: 20667822
    16. Almost all multiple sclerosis patients had cerebrospinal fluid IgG directed to isoforms of one of the oligodendroglial molecules, transketolase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase type I, collapsin response mediator protein 2, and tubulin beta4. PMID: 18676363

    顯示更多

    收起更多

  • 相關疾病:
    Short stature, developmental delay, and congenital heart defects (SDDHD)
  • 蛋白家族:
    Transketolase family
  • 數據庫鏈接:

    HGNC: 11834

    OMIM: 606781

    KEGG: hsa:7086

    STRING: 9606.ENSP00000405455

    UniGene: Hs.89643



主站蜘蛛池模板: 人妻无码精品久久亚瑟影视| 四虎影在永久在线观看| 色综合天天综合欧美综合| 欧美日韩亚洲中文字幕一区二区三区| 国产高清在线精品一区| 俄罗斯大荫蒂女人毛茸茸| 精品国产福利在线视频| 欧美在线精彩视频免费播放| 男受被做哭激烈娇喘gv视频| 中文字幕乱码无码人妻系列蜜桃| 日日摸天天摸人人看| 亚洲精品色情app在线下载观看| 少妇人妻精品一区二区三区| 国产产无码乱码精品久久鸭| 国产成人亚洲综合图区| 国产乱码精品一区二区三区四川人 | 在线观看的av免费网站| 久久精品国产一区二区电影| 久久亚洲私人国产精品| 女同亚洲一区二区无线码| 伊人精品无码av一区二区三区| 小荡货好紧好爽奶头大视频| 久久国产精品一国产精品| 女人高潮抽搐潮喷小视频| 人妻熟女一区二区三区app下载 | 人人妻人人澡人人爽精品日本| 日本一卡二卡不卡视频查询| 四虎永久在线精品视频免费观看| 四虎亚洲精品无码| 精品国产自在现线电影| 日韩欧美猛交xxxxx无码| 2021国产精品一卡2卡三卡4卡| 日韩视频无码免费一区=区三区| 精品卡一卡二卡3卡高清乱码| 国产成人精品男人的天堂| 国产精品麻豆成人av网| 亚洲精品久久久www小说 | 人妻人人做人碰人人添| 中文字幕日韩精品无码内射| 春药高潮抽搐流白浆在线观看| 无码里番纯肉h在线网站|