在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TENM1 Antibody, HRP conjugated

TENM1 Antibody, HRP conjugated

  • 中文名稱(chēng)：
    TENM1兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA892339LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) TENM1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    TENM1 antibody; ODZ1 antibody; TNM1 antibody; Teneurin-1 antibody; Ten-1 antibody; Protein Odd Oz/ten-m homolog 1 antibody; Tenascin-M1 antibody; Ten-m1 antibody; Teneurin transmembrane protein 1) [Cleaved into: Ten-1 intracellular domain antibody; IDten-1 antibody; Ten-1 ICD); Teneurin C-terminal-associated peptide antibody; TCPA-1 antibody; Ten-1 extracellular domain antibody; Ten-1 ECD)] antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Teneurin-1 protein (1-241AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in neural development, regulating the establishment of proper connectivity within the nervous system. May function as a cellular signal transducer.; Plays a role in the regulation of neuroplasticity in the limbic system. Mediates a rapid reorganization of actin- and tubulin-based cytoskeleton elements with an increase in dendritic arborization and spine density formation of neurons in the hippocampus and amygdala. Induces BDNF transcription inhibition in neurons. Activates the mitogen-activated protein (MAP) kinase 2 (MEK2) and extracellular signal-regulated kinase (ERK) cascade. Acts also as a bioactive neuroprotective peptide on limbic neurons of the brain and regulates stress-induced behavior: attenuates alkalosis-associated necrotic cell death and the effects of corticotropin-releasing factor (CRF) on c-fos/FOS induction and on the reinstatement of cocaine seeking.; Induces gene transcription activation.
  • 基因功能參考文獻(xiàn)：
    1. Taken together, the results indicate that distinct pathways are involved in papillary thyroid cancer progression, and TENM1 is a potential marker of cancer progression. PMID: 28004221
    2. ODZ1, a protein that participates in the embryonic development of the brain, is also involved in cancer progression by promoting the growth and invasion capabilities of GSCs via a transcriptional pathway that induces the expression of RhoA and activation of downstream ROCK. PMID: 27641332
    3. Results of our study, that describes a new Tenm1 mouse, agree with the hypothesis that TENM1 has a role in olfaction. However, additional studies should be done in larger Congenital general anosmia (CGA) cohorts, to provide statistical evidence that loss-of-function mutations in TENM1 can solely cause the disease in our and other CGA cases PMID: 27040985
    4. Data suggest teneurin-1/TENM1 (and possibly TENM3) undergoes proteolysis to TCAPs (teneurin C-terminal associated peptides) that form intercellular adhesive units with latrophilin; signaling via TENM1 TCAPs appears to regulate reproduction. [REVIEW] PMID: 26485751
    5. This study identified predicted pathogenic, hemizygous variants on chromosome X in disease genes TENM1. PMID: 25666757
    6. Studies indicate that teneurin-1 has been suggested as a candidate target gene for X-lined mental retardation. PMID: 25152333
    7. The teneurin-1 intracellular domain binds HINT1, thus switching on MITF-dependent transcription of GPNMB. PMID: 25648896
    8. Subsequent analysis showed that the deletion in both cousins was identical and involved the whole SH2D1A gene and a part of the adjacent ODZ1 gene. PMID: 22271700
    9. Data show that human teneurin-1 is directly regulated by EMX2 at a conserved promoter region upstream of the transcription start site, and identify and characterize the EMX2 dependent promoter element of human teneurin-1. PMID: 21651764
    10. teneurin-1 plays a role in intracellular signaling PMID: 15777793

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Single-pass membrane protein.; [Ten-1 intracellular domain]: Nucleus. Nucleus speckle. Nucleus matrix. Cytoplasm, cytoskeleton.; [Teneurin C-terminal-associated peptide]: Nucleus. Cytoplasm. Cell membrane.
  • 蛋白家族：
    Tenascin family, Teneurin subfamily
  • 組織特異性：
    Expressed in fetal brain.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 8117

    OMIM: 300588

    KEGG: hsa:10178

    STRING: 9606.ENSP00000403954

    UniGene: Hs.23796



主站蜘蛛池模板： 18无码粉嫩小泬无套在线观看 | 欧美黑人粗大xxxxbbbb| 亚洲人成网站在线播放小说| 色偷偷亚洲精品一区二区| 国产高清在线精品一区二区三区| 成人片黄网站色大片免费毛片| 综合天堂av久久久久久久| 国产乱码免费卡1卡二卡3| 日本伦奷在线播放| 中国熟妇人妻xxxxx| 精品人妻av一区二区三区| 黄在线看片免费人成视频 | 中国熟妇牲交视频免费| 中国少妇内射xxxhd| 国产精品久久久一区二区三区| 综合无码一区二区三区| 日本一区二区更新不卡| 亚洲性色av性色在线观看| 日日av拍夜夜添久久免费| 精品无码午夜福利理论片| 51社区精品视频| 国产男女免费完整视频在线| 无码办公室丝袜ol中文字幕| yw尤物av无码国产在线观看| 中文字日产乱码免费1～3软件| 亚洲国产成人爱av网站| 未满小14洗澡无码视频网站| 无码国产乱人伦偷精品视频| 亚洲暴爽av人人爽日日碰| 日本免费高清一本视频| 色综合久久无码五十路人妻| 久久成人国产精品免费| 伊人久久大香线蕉综合狠狠| 国内精品久久久久久久97牛牛| 欧美激情精品久久久久久| 亚洲精品suv精品一区二区| 亚洲人成欧美中文字幕| 无遮无挡爽爽免费毛片| 欧美韩中文精品有码视频在线| 亚洲欧美另类精品二区| 亚洲色偷偷偷综合网|