在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TBL1X Antibody

TBL1X Antibody

  • 中文名稱：
    TBL1X兔多克隆抗體
  • 貨號：
    CSB-PA023234LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, A549 whole cell lysate, HepG2 whole cell lysate
      All lanes: TBL1X antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 63, 58 kDa
      Observed band size: 63 kDa
    • Immunofluorescent analysis of Hela cells using CSB-PA023234LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TBL1X Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    EBI antibody; F box like/WD repeat protein TBL1X antibody; F-box-like/WD repeat-containing protein TBL1X antibody; SMAP 55 antibody; SMAP55 antibody; TBL 1 antibody; TBL 1X antibody; TBL1 antibody; TBL1X antibody; TBL1X_HUMAN antibody; Transducin (beta) like 1 antibody; Transducin (beta) like 1 X linked antibody; Transducin (beta) like 1X linked antibody; Transducin beta like 1 X linked antibody; Transducin beta like 1X antibody; Transducin beta like 1X protein antibody; Transducin beta like protein 1, X linked antibody; Transducin beta-like protein 1X antibody; Transducin-beta-like protein 1 antibody; X-linked antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human F-box-like/WD repeat-containing protein TBL1X protein (1-300AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，TBL1X Antibody (CSB-PA023234LA01HU)，的標記方式是Non-conjugated。對于TBL1X Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA023234LB01HU TBL1X Antibody, HRP conjugated ELISA
    FITC CSB-PA023234LC01HU TBL1X Antibody, FITC conjugated
    Biotin CSB-PA023234LD01HU TBL1X Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.
  • 基因功能參考文獻：
    1. TBL1X mRNA and protein expression were significantly increased in the gestational diabetes mellitus placenta. TBL1X is a potential target of miR-138-5p contributed to the abnormal growth of the placenta by enhancing the proliferation of trophoblasts. PMID: 30463081
    2. missense mutations in the gene for TBLR1 that are associated with intellectual disability also prevent MeCP2 binding PMID: 28348241
    3. Targeted SUMOylation of TBL1 and TBLR1 may be a useful strategy for therapeutic treatment of androgen-independent prostate cancer. PMID: 27129164
    4. TBL1X mutations are associated with central hypothyroidism and hearing loss. PMID: 27603907
    5. Here, the authors show that transcriptional co-factor Transducin beta-like (TBL) 1 was over-expressed in both human and murine pancreatic ductal adenocarcinoma and TBL1 deficiency both prevented and reversed pancreatic tumor growth. PMID: 26070712
    6. TBL1 is required to protect GPS2 from degradation, with methylation of GPS2 by arginine methyltransferase PRMT6 regulating the interaction with TBL1 and inhibiting proteasome-dependent degradation. PMID: 26070566
    7. We localized proteins encoded by the top two regulated genes, TBL1X and USH1C, using immunohistochemistry to placental stem and anchoring villi associated with active contractile function. PMID: 23665419
    8. TBL1 and TBLR1 are functionally redundant and essential for transcriptional repression by unliganded thyroid hormone receptors (TR) but not essential for transcriptional activation by liganded TR PMID: 15601853
    9. Mutations within the LisH (LIS1 homology)motif of TBL 1X are likely to result in pathogenic consequences in genes associated with genetic diseases. PMID: 16258276
    10. Wnt signalling induced the interaction between beta-catenin and TBL1-TBLR1, as well as their binding to Wnt target genes. Importantly, the recruitment of TBL1-TBLR1 and beta-catenin to Wnt target-gene promoters was mutually dependent on each other. PMID: 18193033

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    WD repeat EBI family
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 11585

    OMIM: 300196

    KEGG: hsa:6907

    STRING: 9606.ENSP00000217964

    UniGene: Hs.495656



主站蜘蛛池模板： 国产亚洲精品久久久久久牛牛| 狠狠人妻久久久久久综合| 久久婷婷五月综合色精品| 国产成人无码免费视频97| 18禁亚洲深夜福利入口| 牲交a欧美牲交aⅴ免费一| 国产又色又爽又刺激在线观看| 40岁成熟女人牲交片20分钟| 欧美国产国产综合视频| 水蜜桃av无码一区二区| 亚洲制服有码在线丝袜| 2018高清国产一区二区三区| 夜夜春夜夜爽| 亚洲综合无码精品一区二区三区| 在线播放国产精品三级网| 国产在线看片免费视频| 免费人成视频在线播放视频| 女人被狂躁的高潮免费视频| 极品熟妇大蝴蝶20p| 强被迫伦姧惨叫人妻系列| 人妻出差精油按摩被中出| 亚洲乱妇亚洲乱妇xinglu| 国产成人精品亚洲线观看| 日本大片免a费观看视频三区| 高潮喷吹一区二区在线观看| 亚洲精品久久国产精品| 天堂网在线观看| 亚洲 欧美日韩 综合 国产| 国产精品刮毛| 国产重口老太和小伙乱| 欧洲亚洲色视频综合在线| 久久人妻少妇嫩草av| 人妻熟女αⅴ一区二区三区| 日本三级香港三级人妇三| 夜夜欢性恔真人免费视频| 日韩亚洲欧美中文高清在线| 欧美性插b在线视频网站| 天堂а√在线最新版中文| 激烈的性高湖波多野结衣| 少妇仑乱a毛片| 国内精品国产三级国产av|