在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TBL1X Antibody, FITC conjugated

TBL1X Antibody, FITC conjugated

  • 中文名稱：
    TBL1X兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA023234LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TBL1X Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    EBI antibody; F box like/WD repeat protein TBL1X antibody; F-box-like/WD repeat-containing protein TBL1X antibody; SMAP 55 antibody; SMAP55 antibody; TBL 1 antibody; TBL 1X antibody; TBL1 antibody; TBL1X antibody; TBL1X_HUMAN antibody; Transducin (beta) like 1 antibody; Transducin (beta) like 1 X linked antibody; Transducin (beta) like 1X linked antibody; Transducin beta like 1 X linked antibody; Transducin beta like 1X antibody; Transducin beta like 1X protein antibody; Transducin beta like protein 1, X linked antibody; Transducin beta-like protein 1X antibody; Transducin-beta-like protein 1 antibody; X-linked antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human F-box-like/WD repeat-containing protein TBL1X protein (1-300AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.
  • 基因功能參考文獻(xiàn)：
    1. TBL1X mRNA and protein expression were significantly increased in the gestational diabetes mellitus placenta. TBL1X is a potential target of miR-138-5p contributed to the abnormal growth of the placenta by enhancing the proliferation of trophoblasts. PMID: 30463081
    2. missense mutations in the gene for TBLR1 that are associated with intellectual disability also prevent MeCP2 binding PMID: 28348241
    3. Targeted SUMOylation of TBL1 and TBLR1 may be a useful strategy for therapeutic treatment of androgen-independent prostate cancer. PMID: 27129164
    4. TBL1X mutations are associated with central hypothyroidism and hearing loss. PMID: 27603907
    5. Here, the authors show that transcriptional co-factor Transducin beta-like (TBL) 1 was over-expressed in both human and murine pancreatic ductal adenocarcinoma and TBL1 deficiency both prevented and reversed pancreatic tumor growth. PMID: 26070712
    6. TBL1 is required to protect GPS2 from degradation, with methylation of GPS2 by arginine methyltransferase PRMT6 regulating the interaction with TBL1 and inhibiting proteasome-dependent degradation. PMID: 26070566
    7. We localized proteins encoded by the top two regulated genes, TBL1X and USH1C, using immunohistochemistry to placental stem and anchoring villi associated with active contractile function. PMID: 23665419
    8. TBL1 and TBLR1 are functionally redundant and essential for transcriptional repression by unliganded thyroid hormone receptors (TR) but not essential for transcriptional activation by liganded TR PMID: 15601853
    9. Mutations within the LisH (LIS1 homology)motif of TBL 1X are likely to result in pathogenic consequences in genes associated with genetic diseases. PMID: 16258276
    10. Wnt signalling induced the interaction between beta-catenin and TBL1-TBLR1, as well as their binding to Wnt target genes. Importantly, the recruitment of TBL1-TBLR1 and beta-catenin to Wnt target-gene promoters was mutually dependent on each other. PMID: 18193033

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    WD repeat EBI family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11585

    OMIM: 300196

    KEGG: hsa:6907

    STRING: 9606.ENSP00000217964

    UniGene: Hs.495656



主站蜘蛛池模板： 国产日本精品视频在线观看| 18禁黄久久久aaa片| 国产精品无码久久综合网| 久九九久视频精品免费| 99re在线播放| 亚洲国产精品嫩草影院| 青青青伊人色综合久久| 波多野42部无码喷潮在线| 新区乱码无人区二精东| 极品少妇被猛得白浆直喷白浆小说| 中文字幕韩国三级理论| 久久婷婷成人综合色综合 | 中文日产幕无线码6区收藏 | 成人亚洲性情网站www在线观看| 99久久免费精品高清特色大片| 琪琪女色窝窝777777| 久久综合色一综合色88| 亚洲国产制服丝袜先锋| 国产亚洲精品a在线观看下载| 日韩人妻一区二区三区蜜桃视频| 欧美性生交大片免费看| 狠狠躁夜夜躁人人爽天天古典| 色94色欧美sute亚洲线路一| 亚洲国产三级在线观看| 午夜不卡久久精品无码免费| 国产69精品久久久久乱码免费| 青草av久久一区二区三区| 国产专区免费资源网站| 久久精品午夜福利| 久久久精品人妻一区二区三区| 伊人无码精品久久一区二区| 国产午夜人做人免费视频网站| 一二三四社区在线中文视频| 国产一区二区| 国产人妻高清国产拍精品| 在线视频国产网址你懂的| 少妇裸体性生交| 4hu四虎永久免费地址ww416| 无码专区—va亚洲v天堂麻豆| 久久只有这里有精品4| 蜜臀av无码精品人妻色欲|