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  4. TBC1D20 Antibody

TBC1D20 Antibody

  • 中文名稱：
    TBC1D20兔多克隆抗體
  • 貨號(hào)：
    CSB-PA846594LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Mouse brain tissue, Mouse stomach tissue
      All lanes: TBC1D20 antibody at 4μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 46, 20, 49 kDa
      Observed band size: 46 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA846594LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA846594LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA846594LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Western Blot
      Positive WB detected in: A549 whole cell lysate, HepG2 whole cell lysate
      All lanes: TBC1D20 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 46, 20, 49 kDa
      Observed band size: 46 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TBC1D20 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TBC1D20
  • 別名：
    TBC1D20; C20orf140; TBC1 domain family member 20
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human TBC1 domain family member 20 protein (1-237AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，TBC1D20 Antibody (CSB-PA846594LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于TBC1D20 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA846594LB01HU TBC1D20 Antibody, HRP conjugated ELISA
    FITC CSB-PA846594LC01HU TBC1D20 Antibody, FITC conjugated
    Biotin CSB-PA846594LD01HU TBC1D20 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    GTPase-activating protein specific for Rab1 and Rab2 small GTPase families for which it can accelerate the intrinsic GTP hydrolysis rate by more than five orders of magnitude.
  • 基因功能參考文獻(xiàn)：
    1. Warburg Micro syndrome is caused by TBC1D20 deficiency. PMID: 26063829
    2. Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans. PMID: 24239381
    3. The NS5A interaction with TBC1D20 and Rab1 is essential for the viral life cycle. PMID: 22491470
    4. These findings add TBC1D20 to the network of host factors regulating HIV replication cycle. PMID: 22260459
    5. TBC1D20 was found to be the first known GAP for Rab1, which is implicated in the regulation of anterograde traffic between the endoplasmic reticulum and the Golgi complex PMID: 17901050

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  • 相關(guān)疾病：
    Warburg micro syndrome 4 (WARBM4)
  • 亞細(xì)胞定位：
    Membrane; Multi-pass membrane protein.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16133

    OMIM: 611663

    KEGG: hsa:128637

    STRING: 9606.ENSP00000346139

    UniGene: Hs.590876



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