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TBC1D20 Antibody, Biotin conjugated

  • 中文名稱：
    TBC1D20兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA846594LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TBC1D20 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TBC1D20
  • 別名：
    TBC1D20; C20orf140; TBC1 domain family member 20
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human TBC1 domain family member 20 protein (1-237AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    GTPase-activating protein specific for Rab1 and Rab2 small GTPase families for which it can accelerate the intrinsic GTP hydrolysis rate by more than five orders of magnitude.
  • 基因功能參考文獻：
    1. Warburg Micro syndrome is caused by TBC1D20 deficiency. PMID: 26063829
    2. Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans. PMID: 24239381
    3. The NS5A interaction with TBC1D20 and Rab1 is essential for the viral life cycle. PMID: 22491470
    4. These findings add TBC1D20 to the network of host factors regulating HIV replication cycle. PMID: 22260459
    5. TBC1D20 was found to be the first known GAP for Rab1, which is implicated in the regulation of anterograde traffic between the endoplasmic reticulum and the Golgi complex PMID: 17901050

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  • 相關疾病：
    Warburg micro syndrome 4 (WARBM4)
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 數據庫鏈接：

    HGNC: 16133

    OMIM: 611663

    KEGG: hsa:128637

    STRING: 9606.ENSP00000346139

    UniGene: Hs.590876



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