在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TBC1D1 Antibody, FITC conjugated

  • 中文名稱:
    TBC1D1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA803114LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TBC1D1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    KIAA1108 antibody; TBC 1 antibody; TBC antibody; TBC1 (tre 2/USP6; BUB2; cdc16) domain family; member 1 antibody; TBC1 antibody; TBC1 domain family member 1 antibody; Tbc1d1 antibody; TBCD1_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human TBC1 domain family member 1 protein (566-718AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells.
  • 基因功能參考文獻:
    1. TBC1D1-Ser(231) phosphorylation and/or 14-3-3 binding partially mediates AMPK-governed glucose homeostasis and muscle glucose uptake in a context-dependent manner. PMID: 27826658
    2. data demonstrate heterozygous deactivating TBC1D1 mutations in CAKUT patients with a similar renal and ureteral phenotype, and provide evidence that TBC1D1 mutations may contribute to CAKUT PMID: 26572137
    3. AS160 and TBC1D1 phosphorylations were evident 30 min after exercise. PMID: 24876356
    4. Data show that TBC1D1 is expressed and phosphorylated in response to glucose in these cells. PMID: 24239544
    5. Moderate association of rs9852 indicates an influence of TBC1D1 for antipsychotic-induced weight gain. PMID: 23364847
    6. R125W mutation occurs in a location of the TBC1D1 PTB domain that is predicted to have a function in a putative protein:protein interaction. PMID: 23667688
    7. Data suggest that insulin increases phosphorylation of signaling nexus TBC1D1 independent of prior exercise or lipid/Intralipid administration. PMID: 22851577
    8. TBC1D1 is Ser237 phosphorylated and binding capacity to 14-3-3 protein is increased in skeletal muscle following exercise. PMID: 20837646
    9. [review] The question of a mechanism for increased phosphorylation of Ser237-TBC1D1 after exercise has, so far, not had a straightforward experimental approach for a direct answer in humans undergoing in vivo exercise. PMID: 21078596
    10. A single bout of exercise regulates TBC1D1 and AS160 phosphorylation on multiple sites in human skeletal muscle. PMID: 21505148
    11. Crystal structures of human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating protein (RabGAP) domains reveal critical elements for GLUT4 translocation. PMID: 21454505
    12. coding variant R125W affects obesity susceptibility, delimits the location of an obesity gene at 4q34-35 and identifies a gene/gene interaction that influences the risk for obesity predisposition PMID: 16893906
    13. form of Tbc1d1 also inhibited GLUT4 translocation and that this effect also required a functional GAP domain PMID: 17274760
    14. These results confirm a putative role of TBC1D1 R125W variant in familial obesity predisposition. PMID: 18325908

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 數據庫鏈接:

    HGNC: 11578

    OMIM: 609850

    KEGG: hsa:23216

    STRING: 9606.ENSP00000261439

    UniGene: Hs.176503



主站蜘蛛池模板: 久久午夜福利无码1000合集| 国产午夜成人免费看片app| 国产精品av在线| 亚洲妇熟xxxx妇色黄| 青青草无码伊人久久| 一区二区三区毛aaaa片特级| 久爱www成人网免费视频| 玩弄放荡人妻一区二区三区| 亚洲成色最大综合在线| 成人无码午夜在线观看| 国产一区日韩二区欧美三区| 日本少妇被黑人xxxxx| 免费人成在线观看成人片| 精品国产日韩亚洲一区| 人妻去按摩店被黑人按中出| 亚洲精品字幕| 天堂久久天堂av色综合| 亚洲国产精品一区二区成人片国内 | 成人性做爰aaa片免费| 日韩一本之道一区中文字幕| 欧美饥渴熟妇高潮喷水| 天堂最新版在线www官网中文地址 最新国产麻豆aⅴ精品无码 | 国产69久久精品成人看| 国产成人一区二区无码不卡在线| 少妇又色又紧又爽又刺激视频 | 樱花草在线社区www韩国| 色综合亚洲一区二区小说| 内射白嫩少妇超碰| 精品亚洲成a人片在线观看少妇 | 亚洲kkk4444在线观看| 亚洲一区二区三区av天堂| 少妇高潮毛片色欲ava片| 婷婷网亚洲色偷偷男人的天堂 | 国产内射一区亚洲| 美女视频黄频a美女大全| 人人色在线视频播放| 国产午夜福利在线播放87| 国产偷窥熟女精品视频| 日本丰满白嫩大屁股ass| 在线观看潮喷失禁大喷水无码| 99国精品午夜福利视频不卡|