在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TAT Antibody

TAT Antibody

  • 中文名稱：
    TAT兔多克隆抗體
  • 貨號：
    CSB-PA050213
  • 規(guī)格：
    ￥1090
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TAT
  • 別名：
    ATTY_HUMAN antibody; L-tyrosine:2-oxoglutarate aminotransferase antibody; TAT antibody; Tyrosine aminotransferase antibody; Tyrosine aminotransferase; cytosolic antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human TAT.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine.
  • 基因功能參考文獻：
    1. Data analysis did not reveal a genotype-phenotype correlation, but stressed the need of early diagnosis: All patients improved the oculocutaneous lesions after dietary treatment but neurological symptoms prevailed. The discovery of founder mutations in isolated populations, and the benefits of early intervention, should increase diagnostic awareness in newborns. PMID: 28255985
    2. Sequencing of TAT indicated two new homozygous mutations p.L312P (c.935T>C) and p.T408M (c.1223C>T) for the proband and his asymptomatic sister. PMID: 27285949
    3. Two known mutations and one novel mutation was found in the TAT gene of Tunesian Richner-Hanhart syndrome patients. The geographical distribution of RHS mutations shows regional specificities. PMID: 23954227
    4. A paternal inherited frameshift mutation c.1213delCinsAG at codon 405 causing a premature stop codon, and a maternally inherited deletion of 193kb encompassing the complete TAT gene yield the first complete TAT deletion in tyrosinaemia type II described. PMID: 21636300
    5. tumor suppressive mechanism of TAT was associated with its proapoptotic role in a mitochondrial-dependent manner by promoting cytochrome-c release and activating caspase-9 and PARP. PMID: 20209601
    6. two novel missense mutations were identified - (C151Y) and (L273P) within exon 5 and exon 8, respectively in tyrosinemia type II in three unrelated consanguinous Tunisian families PMID: 16574453
    7. a silent exonic transversion in TAT causes complete missplicing by exon 11 skipping in oculocutaneous tyrosinaemia type II PMID: 16917729
    8. Genetically modified adenoviral vector with the protein transduction domain of Tat improves gene transfer to CAR-deficient cells. PMID: 18721127
    9. a heterozygous insertion mutation (c.446_447insA; p.D149DfsX28) was found in exon 4 leading to a frameshift and finally resulting in a premature stop codon and a heterozygous missense mutation (c.658C>T; p.P220S) was identified in exon 5. PMID: 18945316

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Tyrosinemia 2 (TYRSN2)
  • 蛋白家族：
    Class-I pyridoxal-phosphate-dependent aminotransferase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11573

    OMIM: 276600

    KEGG: hsa:6898

    STRING: 9606.ENSP00000348234

    UniGene: Hs.161640



主站蜘蛛池模板： 亚洲乱码日产精品bd在| 狠狠人妻久久久久久综合| 国产精品国产自线拍免费不卡| 日本一卡2卡3卡4卡免费精品| 亚洲bbw性色大片| 亚洲精品一区| 国产成人无码a区视频| 欧美性生交xxxxx无码久久久| 宝宝好涨水快流出来免费视频| 亚洲日韩国产成网在线观看| 欧美成人精品第一区二区三区| 国产极品精品自在线| 国产成人精品a∨一区二区| 无码国模国产在线观看| 丰满女人又爽又紧又丰满| 国产精品无码素人福利| 免费人成网站在线观看视频| 大屁股熟女一区二区三区| а天堂8中文最新版在线官网| 强被迫伦姧惨叫人妻系列| 国产福利一区二区麻豆| 欧美三级在线播放| 亚洲国产成人一区二区在线| 182tv午夜福利在线地址二| 国产成人精品日本亚洲成熟| 免费吃奶摸下激烈视频| 伊人久久综合成人网| 狠狠做久久深爱婷婷| 国产欧美成人一区二区a片| 十八禁视频网站在线观看| 亚洲人成自拍网站在线观看| 无码丰满熟妇bbbbxxx| 亚洲日韩成人av无码网站| 久久久精品久久日韩一区综合| 人妻丰满熟妇av无码区动漫| 国产成a人亚洲精v品无码性色| 欧美激情综合色综合啪啪五月| 东京热加勒比视频一区| 熟妇人妻无码中文字幕| 亚洲最大日夜无码中文字幕 | 成年女人毛片免费观看97|