在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TAT Antibody, Biotin conjugated

  • 中文名稱:
    TAT兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA023175LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TAT Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TAT
  • 別名:
    ATTY_HUMAN antibody; L-tyrosine:2-oxoglutarate aminotransferase antibody; TAT antibody; Tyrosine aminotransferase antibody; Tyrosine aminotransferase; cytosolic antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Tyrosine aminotransferase protein (25-111AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine.
  • 基因功能參考文獻:
    1. Data analysis did not reveal a genotype-phenotype correlation, but stressed the need of early diagnosis: All patients improved the oculocutaneous lesions after dietary treatment but neurological symptoms prevailed. The discovery of founder mutations in isolated populations, and the benefits of early intervention, should increase diagnostic awareness in newborns. PMID: 28255985
    2. Sequencing of TAT indicated two new homozygous mutations p.L312P (c.935T>C) and p.T408M (c.1223C>T) for the proband and his asymptomatic sister. PMID: 27285949
    3. Two known mutations and one novel mutation was found in the TAT gene of Tunesian Richner-Hanhart syndrome patients. The geographical distribution of RHS mutations shows regional specificities. PMID: 23954227
    4. A paternal inherited frameshift mutation c.1213delCinsAG at codon 405 causing a premature stop codon, and a maternally inherited deletion of 193kb encompassing the complete TAT gene yield the first complete TAT deletion in tyrosinaemia type II described. PMID: 21636300
    5. tumor suppressive mechanism of TAT was associated with its proapoptotic role in a mitochondrial-dependent manner by promoting cytochrome-c release and activating caspase-9 and PARP. PMID: 20209601
    6. two novel missense mutations were identified - (C151Y) and (L273P) within exon 5 and exon 8, respectively in tyrosinemia type II in three unrelated consanguinous Tunisian families PMID: 16574453
    7. a silent exonic transversion in TAT causes complete missplicing by exon 11 skipping in oculocutaneous tyrosinaemia type II PMID: 16917729
    8. Genetically modified adenoviral vector with the protein transduction domain of Tat improves gene transfer to CAR-deficient cells. PMID: 18721127
    9. a heterozygous insertion mutation (c.446_447insA; p.D149DfsX28) was found in exon 4 leading to a frameshift and finally resulting in a premature stop codon and a heterozygous missense mutation (c.658C>T; p.P220S) was identified in exon 5. PMID: 18945316

    顯示更多

    收起更多

  • 相關疾病:
    Tyrosinemia 2 (TYRSN2)
  • 蛋白家族:
    Class-I pyridoxal-phosphate-dependent aminotransferase family
  • 數據庫鏈接:

    HGNC: 11573

    OMIM: 276600

    KEGG: hsa:6898

    STRING: 9606.ENSP00000348234

    UniGene: Hs.161640



主站蜘蛛池模板: 亚洲综合久久一区二区| 熟女少妇人妻黑人sirbao| 亚洲图片校园另激情类小说| 国产初高中生真实在线视频| 免费观看黄网站| 综合无码一区二区三区| 国产草莓精品国产av片国产| 国色天香精品一卡2卡3卡4 | 色欲天天婬色婬香综合网完整 | 一区二区传媒有限公司| 四川少妇大战4黑人| 日躁夜躁狠狠躁2001| 99精品热在线在线观看视频| 亚洲精品网站在线观看你懂的 | 动漫无遮挡h纯肉亚洲资源大片| 日日摸日日碰人妻无码老牲| 无码色偷偷亚洲国内自拍| 日本视频免费高清一本18| 国产一卡二卡三新区2022| 久久国产乱子伦免费精品| 特黄特色大片免费播放| 亚洲一区激情校园小说| 18禁无遮挡羞羞啪啪免费网站| 无人区一码卡二卡三乱码| 五月丁香六月综合缴清无码| 国产99视频精品免费专区| 18岁日韩内射颜射午夜久久成人| 无码人妻一区二区三区av | 久久不见久久见免费影院www | 天天摸日日摸狠狠添| 2012中文字幕在线视频| 丁香五月开心婷婷激情综合| 国产精品久久久久影院亚瑟| 久久久午夜精品福利内容| 精品一区二区三人妻视频| 国产女人高潮叫床免费视频| 国产性色播播毛片| 亚洲精品456在线播放| 黑色丝袜脚足国产在线看| 在线 国产 精品 蜜芽| 亚洲成熟丰满熟妇高潮xxxxx|